Decreased uterine vascularization and uterine arterial expansive remodeling with reduced matrix metalloproteinase-2 and -9 in hypertensive pregnancy

Evolving mechanisms of vascular smooth muscle contraction highlight key targets in vascular disease

(2018) Zhongwei Liu et al.   BIOCHEMICAL PHARMACOLOGY

Restoring placental growth factor-soluble fms-like tyrosine kinase-1 balance reverses vascular hyper-reactivity and hypertension in pregnancy

(2016) Minglin Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Adaptive increases in expression and vasodilator activity of estrogen receptor subtypes in a blood vessel-specific pattern during pregnancy

(2015) Karina M. Mata et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia

(2015) Denise C. Cornelius et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

MicroRNA-204 suppresses trophoblast-like cell invasion by targeting matrix metalloproteinase-9

(2015) Yang Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsia

(2015) Dania A. Shah et al.   BIOCHEMICAL PHARMACOLOGY

Genetic, immune and vasoactive factors in the vascular dysfunction associated with hypertension in pregnancy

(2015) Sajjadh MJ Ali et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia

(2015) CHUN-LEI DENG et al.   Experimental and Therapeutic Medicine

Positive correlations between circulating adiponectin and MMP2 in preeclampsia pregnant

(2015) Nibia Mariana Eleuterio et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Early Disturbed Placental Ischemia and Hypoxia Creates Immune Alteration and Vascular Disorder Causing Preeclampsia

(2014) Arturo Zárate et al.   ARCHIVES OF MEDICAL RESEARCH

Metalloproteinase Inhibition Protects against Reductions in Circulating Adrenomedullin during Lead-induced Acute Hypertension

(2014) Regina A. Nascimento et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Altered matrix metalloproteinase-2 and -9 expression/activity links placental ischemia and anti-angiogenic sFlt-1 to uteroplacental and vascular remodeling and collagen deposition in hypertensive pregnancy

(2014) Wei Li et al.   BIOCHEMICAL PHARMACOLOGY

Downregulation of Microvascular Endothelial Type B Endothelin Receptor Is a Central Vascular Mechanism in Hypertensive Pregnancy

(2014) Marc Q. Mazzuca et al.   HYPERTENSION

Pathophysiology of hypertension in pre-eclampsia: a lesson in integrative physiology

(2013) A. C. Palei et al.   Acta Physiologica

EMMPRIN-mediated induction of uterine and vascular matrix metalloproteinases during pregnancy and in response to estrogen and progesterone

(2013) Yiping Dang et al.   BIOCHEMICAL PHARMACOLOGY

Enhanced endothelin receptor type B-mediated vasodilation and underlying [Ca2+]iin mesenteric microvessels of pregnant rats

(2013) Marc Q Mazzuca et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gestational Hypoxia Induces Preeclampsia-Like Symptoms via Heightened Endothelin-1 Signaling in Pregnant Rats

(2013) Jianjun Zhou et al.   HYPERTENSION

Matrix Metalloproteinase Enhances Big-Endothelin-1 Constriction in Mesenteric Vessels of Pregnant Rats With Reduced Uterine Blood Flow

(2013) Ali Abdalvand et al.   HYPERTENSION

Antihypertensive effects of inducible nitric oxide synthase inhibition in experimental pre-eclampsia

(2013) Lorena M. Amaral et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanical Stretch Increases MMP-2 Production in Vascular Smooth Muscle Cells via Activation of PDGFR-β/Akt Signaling Pathway

(2013) Kyo Won Seo et al.   PLoS One

Increased MMPs expression and decreased contraction in the rat myometrium during pregnancy and in response to prolonged stretch and sex hormones

(2012) Zongzhi Yin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Chronic Hypoxia Differentially Up-Regulates Protein Kinase C-Mediated Ovine Uterine Arterial Contraction via Actin Polymerization Signaling in Pregnancy1

(2012) DaLiao Xiao et al.   BIOLOGY OF REPRODUCTION

Physiologic Changes During Normal Pregnancy and Delivery

(2012) Joseph G. Ouzounian et al.   CARDIOLOGY CLINICS

Evaluation of oxidative stress markers in first trimester for assessment of preeclampsia risk

(2011) Habibe Genc et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Physiological Remodelling of the Maternal Uterine Circulation during Pregnancy

(2011) Maurizio Mandala et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway

(2011) Hong-Xia Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Review: The angiogenic and vasodilatory utero-placental network

(2011) G. Valdés et al.   PLACENTA

Trophoblast- and Vascular Smooth Muscle Cell-Derived MMP-12 Mediates Elastolysis during Uterine Spiral Artery Remodeling

(2010) Lynda K. Harris et al.   AMERICAN JOURNAL OF PATHOLOGY

Active matrix metalloproteinase-2 upregulation in the abdominal skin of patients with direct inguinal hernia

(2010) Gemma Pascual et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Prolonged mechanical stretch is associated with upregulation of hypoxia-inducible factors and reduced contraction in rat inferior vena cava

(2010) Chung S. Lim et al.   JOURNAL OF VASCULAR SURGERY

Bovine endometrial metallopeptidases MMP14 and MMP2 and the metallopeptidase inhibitor TIMP2 participate in maternal preparation of pregnancy

(2010) Susanne E. Ulbrich et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Expression of extracellular matrix metalloproteinase inducer (EMMPRIN) and its related extracellular matrix degrading enzymes in the endometrium during estrous cycle and early gestation in cattle

(2010) Birendra Mishra et al.   Reproductive Biology and Endocrinology

Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3Kγ-dependent manner

(2009) Ahmed E. Awad et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats

(2009) Amanda K. Stennett et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vascular Responses to Hypoxia and Ischemia

(2009) Gregg L. Semenza   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Enhanced expressions of matrix metalloproteinase (MMP)-2 and –9 and vascular endothelial growth factors (VEGF) and increased microvascular density in the endometrial hyperplasia of women with anovulatory dysfunctional uterine bleeding

(2009) Xinmei Zhang et al.   FERTILITY AND STERILITY

Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy

(2009) Martina Montagnana et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Non-proteinuric pre-eclampsia: a novel risk indicator in women with gestational hypertension

(2009) Caroline SE Homer et al.   JOURNAL OF HYPERTENSION

Pregnancy outcome and fibrinolytic, endothelial and coagulation markers in women undergoing uterine artery Doppler screening at 23 weeks

(2009) B. J. HUNT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Differential [Ca2+]i signaling of vasoconstriction in mesenteric microvessels of normal and reduced uterine perfusion pregnant rats

(2008) Wensheng Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

TRANSIENT RECEPTOR POTENTIAL (TRP) CHANNELS, VASCULAR TONE AND AUTOREGULATION OF CEREBRAL BLOOD FLOW

(2008) Joseph E Brayden et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Hypertension in Response to Chronic Reductions in Uterine Perfusion in Pregnant Rats

(2008) Babbette LaMarca et al.   HYPERTENSION

Hypertension Produced by Placental Ischemia in Pregnant Rats Is Associated With Increased Soluble Endoglin Expression

(2008) Jeffrey S. Gilbert et al.   HYPERTENSION

MMP-2 Induced Vein Relaxation via Inhibition of [Ca2+]e-Dependent Mechanisms of Venous Smooth Muscle Contraction. Role of RGD Peptides

(2008) Joseph D. Raffetto et al.   JOURNAL OF SURGICAL RESEARCH

Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease

(2007) Joseph D. Raffetto et al.   BIOCHEMICAL PHARMACOLOGY