Clinically Meaningful Responses to Dupilumab in Adolescents with Uncontrolled Moderate-to-Severe Atopic Dermatitis: Post-hoc Analyses from a Randomized Clinical Trial

Dupilumab provides important clinical benefits to patients with atopic dermatitis who do not achieve clear or almost clear skin according to the Investigator's Global Assessment: a pooled analysis of data from two phase III trials

(2019) J.I. Silverberg et al.   BRITISH JOURNAL OF DERMATOLOGY

Peak Pruritus Numerical Rating Scale: psychometric validation and responder definition for assessing itch in moderate‐to‐severe atopic dermatitis

(2019) G. Yosipovitch et al.   BRITISH JOURNAL OF DERMATOLOGY

Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis

(2019) Eric L. Simpson et al.   JAMA Dermatology

Responder Threshold for Patient-Oriented Eczema Measure (POEM) and Children’s Dermatology Life Quality Index (CDLQI) in Adolescents with Atopic Dermatitis

(2019) Eric L. Simpson et al.   Dermatology and Therapy

Use of systemic corticosteroids for atopic dermatitis: International Eczema Council consensus statement

(2018) A.M. Drucker et al.   BRITISH JOURNAL OF DERMATOLOGY

Early-onset pediatric atopic dermatitis is characterized by T H 2/T H 17/T H 22-centered inflammation and lipid alterations

(2018) Patrick M. Brunner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I

(2018) A. Wollenberg et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma

(2018) Klaus F. Rabe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma

(2018) Mario Castro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of Inadequately Controlled Disease and Disease Severity With Patient-Reported Disease Burden in Adults With Atopic Dermatitis

(2018) Eric L. Simpson et al.   JAMA Dermatology

Major Comorbidities of Atopic Dermatitis: Beyond Allergic Disorders

(2018) Amy Paller et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Prescribing practices for systemic agents in the treatment of severe pediatric atopic dermatitis in the US and Canada: The PeDRA TREAT survey

(2017) Christine R. Totri et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial

(2017) Andrew Blauvelt et al.   LANCET

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

(2016) Sally Wenzel et al.   LANCET

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

(2016) Diamant Thaçi et al.   LANCET

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

(2016) Eric L. Simpson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atopic dermatitis from adolescence to adulthood in the TOACS cohort: prevalence, persistence and comorbidities

(2015) C. G. Mortz et al.   ALLERGY

What the Eczema Area and Severity Index score tells us about the severity of atopic dermatitis: an interpretability study

(2015) Y.A. Leshem et al.   BRITISH JOURNAL OF DERMATOLOGY

Atopic and nonatopic eczema in adolescence: is there a difference?

(2015) E.K. Johansson et al.   BRITISH JOURNAL OF DERMATOLOGY

Suicidal Ideation, Mental Health Problems, and Social Function in Adolescents with Eczema: A Population-Based Study

(2014) Jon A. Halvorsen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Guidelines of care for the management of atopic dermatitis

(2014) Robert Sidbury et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis

(2014) Lisa A. Beck et al.   NEW ENGLAND JOURNAL OF MEDICINE

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes

(2014) L. E. Macdonald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

(2014) A. J. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Off-label prescribing for allergic diseases in children

(2014) Diana Silva et al.   World Allergy Organization Journal

EASI, (objective) SCORAD and POEM for atopic eczema: responsiveness and minimal clinically important difference

(2011) M. E. Schram et al.   ALLERGY

Depression, anxiety, and dermatologic quality of life in adolescents with atopic dermatitis

(2011) Marcia J. Slattery et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Specificity in the association of anxiety, depression, and atopic disorders in a community sample of adolescents

(2010) Marcia J. Slattery et al.   JOURNAL OF PSYCHIATRIC RESEARCH