Leveraging genetically simple traits to identify small-effect variants for complex phenotypes

How old are quantitative trait loci and how widely do they segregate?

(2015) K.E. Kemper et al.   JOURNAL OF ANIMAL BREEDING AND GENETICS

minimac2: faster genotype imputation

(2014) Christian Fuchsberger et al.   BIOINFORMATICS

Selection for complex traits leaves little or no classic signatures of selection

(2014) Kathryn E Kemper et al.   BMC GENOMICS

Identification of the putative ancestral allele of bovine single-nucleotide polymorphisms

(2014) D. Rocha et al.   JOURNAL OF ANIMAL BREEDING AND GENETICS

Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle

(2014) Hans D Daetwyler et al.   NATURE GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Expression Variants of the Lipogenic AGPAT6 Gene Affect Diverse Milk Composition Phenotypes in Bos taurus

(2014) Mathew D. Littlejohn et al.   PLoS One

A Multi-Trait, Meta-analysis for Detecting Pleiotropic Polymorphisms for Stature, Fatness and Reproduction in Beef Cattle

(2014) Sunduimijid Bolormaa et al.   PLoS Genetics

RNA-Seq optimization with eQTL gold standards

(2013) Shannon E Ellis et al.   BMC GENOMICS

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Improving accuracy of genomic predictions within and between dairy cattle breeds with imputed high-density single nucleotide polymorphism panels

(2012) M. Erbe et al.   JOURNAL OF DAIRY SCIENCE

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Genome-Wide Association Study Identifies Loci for Body Composition and Structural Soundness Traits in Pigs

(2011) Bin Fan et al.   PLoS One

SLC37A1 and SLC37A2 Are Phosphate-Linked, Glucose-6-Phosphate Antiporters

(2011) Chi-Jiunn Pan et al.   PLoS One

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Sizing up human height variation

(2008) Peter M Visscher   NATURE GENETICS

High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

(2008) Jean-Baptiste Veyrieras et al.   PLoS Genetics