Article
Food Science & Technology
Manita Adhikari, Sushil Koirala, Anil Kumar Anal
Summary: This study successfully developed an edible multilayer coating using chitosan-pectin biopolymers deposited by electrostatic layer-by-layer deposition (LbL) to extend the shelf life of strawberries. The application of this coating on strawberries at room temperature was able to significantly prolong their shelf life while maintaining their texture and color.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Polymer Science
Muhammad Imran Azman, Jirasuta Chungprempree, Jitima Preechawong, Pornsri Sapsrithong, Manit Nithitanakul
Summary: In this study, amines electrolyte solution was used with layer-by-layer technique to modify highly porous polymer, increasing its CO2 adsorption capacity. By utilizing polyHIPE prepared from styrene and divinylbenzene with varying ratios and modifying the surface with LbL technique, improvements were made in surface area, thermal properties, and mechanical properties. The modified material showed the highest CO2 adsorption capacity with the use of PEI, maintaining an open cell structure suitable for adsorption technology.
Article
Chemistry, Applied
Jinfa Qin, Jinping Zhao, Yang Wu, Long Li, Dan Li, Hongbing Deng, Jinping Liu, Li Zhang
Summary: In recent years, the morbidity of esophageal diseases has been increasing, and postoperative bacterial infection is a common potential risk. However, current research on artificial esophageal stents is unsatisfactory. In this study, chitosan and collagen were used to modify nanofibrous mats, which exhibited excellent biocompatibility and antibacterial activity. The mats promoted the adhesion and proliferation of human esophageal epithelial cells. Animal experiments showed that the mats were beneficial for the healing of esophageal defects.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Elnaz Shaabani, Maryam Sharifiaghdam, Herlinde De Keersmaecker, Riet De Rycke, Stefaan De Smedt, Reza Faridi-Majidi, Kevin Braeckmans, Juan C. Fraire
Summary: Chitosan-coated gold nanoparticles fabricated through a layer by layer self-assembly method show excellent protection of siRNA, good cellular uptake, and improved RNA silencing effect. This work highlights the potential of LBL assembled CS-AuNPs as promising nanocarriers for enhanced intracellular siRNA delivery and silencing.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Green & Sustainable Science & Technology
Zongqian Wang, Yingping Wan, Xianhong Zheng, Haiwei Yang, Peng Wang, Changlong Li
Summary: This study introduces a novel layer-by-layer self-assembly strategy to fabricate Zr(IV) modified down fibers with high loading, excellent radiative heating performance, and good washability. The surface temperature of Zr(IV) modified down fibers increases by 3.75 degrees C after exposure to infrared radiation, surpassing currently available chemical modified down fibers. Moreover, the radiative heating performance of Zr(IV) modified down fibers only deteriorates by less than 5% after 8 wash cycles, demonstrating impressive washability.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Chemistry, Multidisciplinary
Daniel Krizak, Mahsa Abbaszadeh, Santanu Kundu
Summary: Thin-film composite membranes with a polyamide active layer are widely used in desalination applications, with the layer-by-layer approach providing precise control over the properties of the active layer. The automated spin-assisted version of this method reduces human error and improves repeatability. By using polyvinylidene fluoride as a more robust support and utilizing levodopa as an interlayer prior to the deposition of the polyamide layer, the membranes show moderate permeability and higher selectivity for sodium chloride.
SEPARATION SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Nemany A. N. Hanafy
Summary: Curcumin, a potential candidate in cancer therapy, can be improved in its accumulation and release inside cancer cells by functionalized multi-layered polyelectrolyte capsules.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Reut Gal, Neriya Perez-Lapid, Yael Zvulunov, Adi Radian
Summary: E. coli cells overexpressing atrazine chlorohydrolase were coated using layer-by-layer self-assembly to create positively charged bio-hybrid capsules for efficient herbicide degradation. The physio-chemical properties of the bacteria/polymer interface were studied with a focus on surface modification and activity enhancement. The resulting coated cells exhibited improved stability, dispersion, and activity, showing a promising avenue for sustainable bioremediation and biocatalytic platforms.
Article
Polymer Science
Alireza Eivazi, Bruno Medronho, Bjorn Lindman, Magnus Norgren
Summary: In this study, cellulose-based core-shell particles were developed using the Layer-by-Layer (LbL) technique by alternating two cellulose derivatives onto a cationic vesicular template. The size of the particles could be tuned by controlling the number of layers deposited, with pH having a significant effect on the process. This work demonstrates the electrostatic driving force for LbL deposition and the potential advantages of using biobased containers for pharmaceutical and biomedical applications.
Article
Engineering, Electrical & Electronic
Hui Xia, Dongzhi Zhang, Dongyue Wang, Mingcong Tang, Hao Zhang, Xiaoya Chen, Ruiyuan Mao, Yanhua Ma, Haolin Cai
Summary: This study demonstrates a piezoresistive pressure sensor prepared by layer-by-layer self-assembly of MXene and carbon black, which exhibits high sensitivity, wide sensing range, and acceptable response time. Additionally, the sensor can sensitively capture micropressure signals and control smart devices through external pressure, making it highly versatile and applicable.
IEEE SENSORS JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Tae Kyung Won, Jinkyu Roh, Dong June Ahn
Summary: The study developed a sensory figure multilayer by immobilizing diacetylene (DA) vesicles on a substrate using silica nanoparticles shell. The vesicles were enhanced with surface activity and structural stability by forming a dense shell of silica nanoparticles. Alphabet patterning was achieved to create visible and fluorescent sensors, which showed rapid recognition of chemical stimuli. The manufactured patterning sensory figure demonstrated long-lasting functionality.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Article
Chemistry, Physical
Alan F. Y. Matsushita, Josias R. V. Nascimento, Joao M. A. Leite, Christiana A. Pessoa, Jarem R. Garcia
Summary: This paper presents the synthesis and characterization of ZnO nanoparticles stabilized in poly-(diallyldimethylammonium chloride) polymer (ZnO-PDDA). The TEM images revealed ellipsoid-shaped ZnO nanoparticles with diameters ranging from 100-500 nm. The cotton fibers were functionalized using the LbL method with Ag and ZnO nanoparticles, resulting in excellent photocatalytic activity and minimal particle detachment after multiple washes.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Materials Science, Multidisciplinary
Fangfang Dai, Jia Yu, Mengqin Yuan, Zhimin Deng, Yanqing Wang, Yaqi Fan, Hongbing Deng, Yanxiang Cheng
Summary: The development of a novel, biocompatible mesh for the treatment of pelvic organ prolapse using chitosan and collagen coating on nanofiber mats has shown promising results in facilitating cell growth and demonstrating excellent antibacterial activity. Through systematic chemical characterization and cell biology experiments, the modified mesh has shown significant changes in composition and structure, indicating its potential as implant material for pelvic organ prolapse patients.
MATERIALS & DESIGN
(2021)
Article
Chemistry, Multidisciplinary
Muhammad Usman Khan, Wajid Rehman, Saira Bibi, Mohammed M. Alanazi, Ashwag S. Alanazi, Liaqat Rasheed, Shoaib Khan, Syed Umar Tariq Gillani, Arslan Tauqeer
Summary: Chitosan-based silver-doped titanium dioxide (Cs-AgTiO2) films were successfully synthesized and characterized. The films exhibited excellent antibacterial, antifungal, and nematicidal activities, making them a promising material for controlling nematodes in food.
Article
Biochemistry & Molecular Biology
Nelson Naveas, Ruth Pulido, Vicente Torres-Costa, Fernando Agullo-Rueda, Mauricio Santibanez, Francisco Malano, Gonzalo Recio-Sanchez, Karla A. Garrido-Miranda, Miguel Manso-Silvan, Jacobo Hernandez-Montelongo
Summary: This study proposes the formation of antibacterial films with silver nanoparticles embedded in carboxymethylcellulose/chitosan multilayers by the layer-by-layer method. The films exhibited high antibacterial activity against both Escherichia coli and Staphylococcus aureus, indicating their potential for biomedical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Polymer Science
Dominik de Cassan, Alexander Becker, Birgit Glasmacher, Yvonne Roger, Andrea Hoffmann, Thomas R. Gengenbach, Christopher D. Easton, Robert Hansch, Henning Menzel
JOURNAL OF APPLIED POLYMER SCIENCE
(2020)
Article
Biophysics
Yvonne Roger, Steffen Sydow, Laura Burmeister, Henning Menzel, Andrea Hoffmann
COLLOIDS AND SURFACES B-BIOINTERFACES
(2020)
Article
Engineering, Biomedical
Julius Sundermann, Sarah Oehmichen, Steffen Sydow, Laura Burmeister, Bastian Quaas, Robert Haensch, Ursula Rinas, Andrea Hoffmann, Henning Menzel, Heike Bunjes
Summary: Different surface modifications of PCL fiber mats influence the binding and release of BMP-2, with polydopamine coating showing the highest binding capacity. Functionalization with chitosan nanogel considerably increases BMP-2 binding on all hydrophilized surfaces and results in sustained release without loss of bioactivity.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2021)
Article
Pharmacology & Pharmacy
Julius Sundermann, Steffen Sydow, Laura Burmeister, Andrea Hoffmann, Henning Menzel, Heike Bunjes
Summary: This study investigated the release performance of BMP-2 from PCL fiber mat-based implant prototypes coated with chitosan nanogel, highlighting the significant effects of chitosan and solubilizing additives on the recovery rate of BMP-2 in in vitro release experiments.
Article
Polymer Science
Henrik-Alexander Christ, Yannick Bourgat, Henning Menzel
Summary: The optimization of polysaccharide chitosan conjugation with functional carboxylic acids using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and hydroxy benzotriazole was demonstrated, showing resource-efficient synthesis of highly functionalized chitosan with optimal parameters. Catalytic amounts of hydroxy benzotriazole and tight pH control in the reaction mixture led to efficient incorporation of desired moieties as side chains in chitosan. Results showed high degree of substitution and coupling efficacy for various carboxylic acids, indicating broad applicability for chitosan functionalization.
Article
Infectious Diseases
Yannick Bourgat, Carina Mikolai, Meike Stiesch, Philipp Klahn, Henning Menzel
Summary: The controlled release of antibacterial agents through nanogels has been shown to be effective in managing peri-implant infections. However, the efficacy of the released drug may be hindered by residual linkers. The feasibility of enzyme-triggered drug release has been successfully demonstrated.
Article
Polymer Science
Henrik-Alexander Christ, Pen Yiao Ang, Fuzhao Li, Hans-Hermann Johannes, Wolfgang Kowalsky, Henning Menzel
Summary: Micron-sized PMMA polymer optical fibers doped with rhodamine B as an organic dye were successfully fabricated using stable jet electrospinning (SJES) method, producing defect-free fibers with a smooth surface and diameter of about 20 µm. Photoluminescence spectra of the doped fibers showed a narrow excitation peak with low lasing threshold, indicating the potential for SJES to be a new source of amplified optics components or organic solid-state fiber lasers.
JOURNAL OF POLYMER SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Mandy Mokrus, Henning Menzel
Summary: Amphiphilic block copolymers with a thermoresponsive poly(N-isopropylacrylamide) block and a glycopeptide block were synthesized and investigated for their particle formation and interaction with lectins. The results showed that the saccharide moieties were located on the surface of the particles and the interaction between the glycosylated particles and lectins became stronger at 37 degrees C.
MACROMOLECULAR BIOSCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Fuzhao Li, Lars F. Klepzig, Nils Keppler, Peter Behrens, Nadja C. Bigall, Henning Menzel, Jannika Lauth
Summary: In this study, we demonstrate the fabrication of photoluminescent polymer-encapsulated 2D CdSe/CdS NPLs nanocomposite coatings using the LbL deposition technique. The repulsive forces between the NPLs are increased to form flat-arranged nanocomposites, and the photoluminescence properties are successfully retained. This approach allows for the preparation of stable polymer-encapsulated CdSe/CdS NPLs in smooth coatings with controllable film thickness.
Article
Materials Science, Multidisciplinary
Henrik-Alexander Christ, Henning Menzel
Summary: The main objective of this study is to understand and optimize the electrospinning process for highly modified fungal chitosan. By systematically varying the process parameters, the key parameters affecting the spinning solution properties have been identified, and methods for avoiding instabilities and producing uniform and defect-free nanofibers have been established.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2023)
Article
Biotechnology & Applied Microbiology
Katharina Doll-Nikutta, Andreas Winkel, Ines Yang, Anna Josefine Grote, Nils Meier, Mosaieb Habib, Henning Menzel, Peter Behrens, Meike Stiesch
Summary: This study provides insights into the initial adhesion of oral bacteria and supports the development of infection-resistant implant materials in the future.
BIOENGINEERING-BASEL
(2022)
Article
Materials Science, Multidisciplinary
Xu Liu, Fuzhao Li, Manuel Hohgardt, Lars Frederik Klepzig, Marcel Maximilian Willich, Henrik-Alexander Christ, Andreas Schaate, Peter Behrens, Jannika Lauth, Henning Menzel, Peter Jomo Walla
Summary: Stable jet electrospinning (SJES) is a special optical fiber generation technique that prevents chaotic fiber whipping. Incorporating highly emissive semiconductor nanoplatelets (NPLs) in SJES fibers has great potential in various fields. This study reports the observation of perpendicular alignment of rectangular CdSe/CdS 2D-NLP in SJES fibers, resulting in dominant emission parallel to the fiber.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2023)
Article
Biotechnology & Applied Microbiology
Henrik-Alexander Christ, Nils Peter Daniel, Jennifer Solarczek, Leonard Sebastian Fresenborg, Anett Schallmey, Henning Menzel
Summary: This study demonstrates the successful immobilization of catalytically active biomolecules onto electrospun chitosan nanofiber meshes. The immobilized enzyme exhibited high stability and maintained its activity for over 7 days of storage. The hydrophilic chitosan support matrix enabled continuous oxidation reactions with constant turnover, showcasing the potential applications of these fibers.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Fuzhao Li, Henning Menzel
Summary: This study investigates the electrospinning process of cyclic olefin copolymer (COC) fibers and finds that the use of specific solvent systems can improve the morphology and alignment of the fibers. By adding dyes and nanoplatelets, dye-doped COC fibers can be produced without compromising their optical performance.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2023)
Article
Engineering, Biomedical
Merle Kempfert, Elmar Willbold, Sebastian Loewner, Cornelia Blume, Johannes Pitts, Henning Menzel, Yvonne Roger, Andrea Hoffmann, Nina Angrisani, Janin Reifenrath
Summary: Chronic tendon ruptures are common in orthopedics and the use of traditional surgical methods with implants is necessary. The study demonstrated the potential of 3D-printed PCL scaffolds as suitable candidates for tendon implants, with enhanced cytocompatibility achieved through surface modifications.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2022)
