Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats

Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats

(2019) Laura G. Sánchez-Lozada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Are Liquid Sugars Different from Solid Sugar in Their Ability to Cause Metabolic Syndrome?

(2019) Gerhard Sundborn et al.   Obesity

Impact of dietary sucrose on adiposity and glucose homeostasis in C57BL/6J mice depends on mode of ingestion: liquid or solid

(2019) Jacques Togo et al.   Molecular Metabolism

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease

(2018) Thomas Jensen et al.   JOURNAL OF HEPATOLOGY

Diet high in fructose promotes liver steatosis and hepatocyte apoptosis in C57BL/6J female mice: Role of disturbed lipid homeostasis and increased oxidative stress

(2017) Youngshim Choi et al.   FOOD AND CHEMICAL TOXICOLOGY

Investigating the effects of an oral fructose challenge on hepatic ATP reserves in healthy volunteers: A 31P MRS study

(2016) S.J. Bawden et al.   CLINICAL NUTRITION

Added sugars and risk factors for obesity, diabetes and heart disease

(2016) J M Rippe et al.   INTERNATIONAL JOURNAL OF OBESITY

Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism

(2016) Xingyong Wan et al.   JOURNAL OF HEPATOLOGY

A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer

(2016) Amon Asgharpour et al.   JOURNAL OF HEPATOLOGY

Chronic NOS inhibition accelerates NAFLD progression in an obese rat model

(2015) Ryan D. Sheldon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cidec promotes the differentiation of human adipocytes by degradation of AMPKα through ubiquitin-proteasome pathway

(2015) Yuqiao Xu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Xanthine oxidase in non-alcoholic fatty liver disease and hyperuricemia: One stone hits two birds

(2015) Chengfu Xu et al.   JOURNAL OF HEPATOLOGY

A pilot study on the impact of a low fructose diet and allopurinol on clinic blood pressure among overweight and prehypertensive subjects: a randomized placebo controlled trial

(2015) Magdalena Madero et al.   Journal of the American Society of Hypertension

Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes

(2014) Yea-Jin Choi et al.   LABORATORY INVESTIGATION

Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes

(2012) Manal F. Abdelmalek et al.   HEPATOLOGY

Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress

(2012) Miguel A. Lanaspa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver

(2012) Miguel A. Lanaspa et al.   PLoS One

Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake

(2011) Carlos A. Roncal-Jimenez et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A Physiological Role for Fat Specific Protein 27/Cell Death-Inducing DFF45-Like Effector C in Adipose and Liver

(2010) Kimihiko Matsusue   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

Functional analysis of FSP27 protein regions for lipid droplet localization, caspase-dependent apoptosis, and dimerization with CIDEA

(2009) Kun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response

(2009) S E Perez-Pozo et al.   INTERNATIONAL JOURNAL OF OBESITY

Oxidative stress induced lipid accumulation via SREBP1c activation in HepG2 cells

(2008) Mika Sekiya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatic Steatosis in Leptin-Deficient Mice Is Promoted by the PPARγ Target Gene Fsp27

(2008) Kimihiko Matsusue et al.   Cell Metabolism

Relationship between oxidative stress and mitochondrial function in the post-conditioned heart

(2008) Francisco Correa et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES