Article
Chemistry, Physical
Abdollah Neshat, Mahdi Cheraghi, Monika Kucerakova, Michal Dusek, Ali Mousavizadeh Mobarakeh
Summary: The synthesis and characterization of a new Cu(II) complex with a bidentate Schiff base were reported. The structure of CuL2 was determined using single crystal X-ray diffraction, revealing a square planar geometry with two naphthyl substituents perpendicular to the molecular plane. Additional analysis was conducted using IR and UV-Visible spectroscopy techniques. The catalytic activity of CuL2 in the oxidation of primary and secondary alcohols was investigated, with TBHP and imidazole identified as an effective oxidant/additive combination.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Mihaela Mureseanu, Mihaela Filip, Irina Bleotu, Cezar Ionut Spinu, Alexandru Horia Marin, Iulia Matei, Viorica Parvulescu
Summary: A new series of Cu(II) and Mn(II) complexes with Schiff base ligands derived from 2-furylmethylketone (Met), 2-furaldehyde (Fur), and 2-hydroxyacetopheneone (Hyd) have been synthesized on functionalized SBA-15-NH2, MCM-48-NH2, and MCM-41-NH2 supports. The hybrid materials were characterized by various techniques and their catalytic performances in oxidation reactions were evaluated. The best catalytic activity was observed for the SBA-15-NH2-MetMn catalyst in the oxidation of cyclohexene, and no leaching was observed for Cu and Mn complexes.
Article
Green & Sustainable Science & Technology
Clement Jacquot, Vesna Middelkoop, Angela Koeckritz, Andrej Pohar, Regina Bienert, Suela Kellici, Ioan-Alexandru Baragau, Baldassarre Venezia, Asterios Gavriilidis, Blaz Likozar, Andrew M. Beale
Summary: This study introduces novel patterned monolithic reactors as potential replacements for conventional packed bed and batch reactors in the chemical industry. By utilizing bimetallic formulations, including earth-abundant metals like iron, higher conversion rates and TOF values were achieved in the selective oxidation of benzyl alcohol. Mathematical modeling provided insights into the physical and chemical processes governing reactant conversion, highlighting the advantages of the novel design.
SUSTAINABLE MATERIALS AND TECHNOLOGIES
(2021)
Review
Biochemistry & Molecular Biology
Maria Stefania Sinicropi, Jessica Ceramella, Domenico Iacopetta, Alessia Catalano, Annaluisa Mariconda, Camillo Rosano, Carmela Saturnino, Hussein El-Kashef, Pasquale Longo
Summary: This article summarizes the important role of metal complexes in pharmaceutical sciences, focusing on the antimicrobial and antiproliferative activities of Schiff bases (SBs) metal complexes, as well as recent studies on various biological activities of mononuclear and binuclear SB complexes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Mohammed Khaled Bin Break, Tan Yew Fung, May Zie Koh, Wan Yong Ho, Mohamed Ibrahim Mohamed Tahir, Omar Ashraf Elfar, Rahamat Unissa Syed, Weam M. A. Khojali, Turki Mubarak Alluhaibi, Bader Huwaimel, Christophe Wiart, Teng-Jin Khoo
Summary: A series of novel macroacyclic Schiff base ligands and their Cu (II) complexes were synthesized and evaluated for their anticancer and antibacterial activities. Among them, Cu1 showed the highest cytotoxic activity against breast cancer cells, while compound 3 exhibited the most potent antibacterial activity against K. rhizophila and S. aureus. The results suggested that these compounds have potential applications as anticancer and antibacterial agents.
Article
Chemistry, Multidisciplinary
Lahinakillathu Nishana, Ayyamperumal Sakthivel, M. R. Prathapachandra Kurup, Krishna K. Damodaran, Antonysamy Kulandaisamy, Sithambaresan Maheswaran
Summary: The structural characteristics of a series of copper(II) complexes were investigated using spectroscopic and analytical methods. The crystal structures of aroylhydrazone, APMB and copper complex 4 were resolved using single-crystal X-ray diffraction studies. The copper(II) complexes showed promising catalytic activity in the oxidation of cinnamyl alcohol, with complex 1 exhibiting the highest activity.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Grzegorz Romanowski, Justyna Budka, Iwona Inkielewicz-Stepniak
Summary: New oxidovanadium(V) complexes and cis-dioxidomolybdenum(VI) complexes with chiral Schiff bases were characterized and studied for their catalytic, cytotoxic, and cytoprotective activities. The oxidovanadium(V) complexes showed higher cytotoxicity and no cytoprotective ability against H2O2-induced cytotoxicity.
Article
Biochemistry & Molecular Biology
Anna Sykula, Adriana Nowak, Eugenio Garribba, Aliaksandr Dzeikala, Magdalena Rowinska-Zyrek, Justyna Czerwinska, Waldemar Maniukiewicz, Elzbieta Lodyga-Chruscinska
Summary: The three Schiff base ligands derived from hesperetin and their copper complexes were studied and characterized by various spectroscopic methods. The genotoxic activity of the compounds was tested on cancer cell lines and normal cell lines. The results showed that the ligands acted as neutral tridentate ligands in the acetate complexes, and the copper complexes displayed lower genotoxicity compared to the ligands in HeLa cells. In Caco-2 cells, HHSB and HTSC induced the most DNA damage, while CuHHSB and CuHTSC induced the highest DNA damage in LLC-PK1 cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Inorganic & Nuclear
Suhong Qiu, Yanlin Li, Henan Xu, Man Zhou, Qian Liang, Jian Rong, Zhongyu Li, Song Xu
Summary: In this study, tetra-[alpha-(p-formyl) phenoxy] phthalocyanine cobalt (II)/multiwalled carbon nanotubes (CoPc/ MWCNTs) composites were prepared through the interaction between CoPc and MWCNTs. The structures of the composites were characterized using UV-vis spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, and transmission electron microscopy. The catalytic efficiency of the composites in the oxidation reaction of benzyl alcohol was investigated under different reaction parameters.
SOLID STATE SCIENCES
(2022)
Article
Chemistry, Inorganic & Nuclear
Abdollah Neshat, Farzane Osanlou, Meysam Kakavand, Piero Mastrorilli, Emanuela Schingaro, Ernesto Mesto, Stefano Todisco
Summary: Four Schiff base manganese(III) complexes with derivatives of [(R,R)-N,N'-bis(salicy1idene)-1,2-cyclohexanediaminato)] were synthesized and characterized, showing good catalytic activity in oxidation reactions. Among them, Mn-4 complex was the most stable and selected for the oxidation of various alcohols, demonstrating promising potential for practical applications.
Article
Nanoscience & Nanotechnology
Pingping Wu, Zhengke He, Yonghui Liu, Lei Song, Chunzheng Wang, Edgar Muhumuza, Peng Bai, Lianming Zhao, Svetlana Mintova, Zifeng Yan
Summary: The study found that a modified catalyst consisting of nanosized Au-Pd particles with SnOx can enhance benzaldehyde selectivity by modulating the affinity of reactants and products on the catalyst surface through redox switching. Additionally, the presence of SnOx promotes improved catalytic activity.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Medicinal
Jingmin Cui, Xia Ji, Yingqi Mi, Qin Miao, Fang Dong, Wenqiang Tan, Zhanyong Guo
Summary: In this study, N-2-hydroxypropyltrimethyl ammonium chitosan derivatives with good biological activities were prepared through ion exchange reaction. These derivatives showed significantly improved antibacterial and antifungal activities, with particularly good inhibitory effects on Staphylococcus aureus and Escherichia coli.
Article
Chemistry, Physical
Ahmed A. Farag, Arafat Toghan, Mohsen S. Mostafa, Chen Lan, Guanglu Ge
Summary: This study investigates the protective properties of efficient Schiff's base inhibitors on the environment and metals, and evaluates the corrosion inhibition performance of GSB-I and GSB-II on steel. The results demonstrate that GSB-I and GSB-II exhibit good corrosion inhibition efficiency, and also show potential biological activities against fungi, bacteria, and sulfate-reducing bacteria. The molecular configurations of GSB-I and GSB-II are found to influence the corrosion inhibition behavior in acidic environments, as determined by calculations and simulations.
Article
Chemistry, Physical
Chiara Pischetola, Stephen M. Francis, Federico Grillo, Christopher J. Baddeley, Fernando Cardenas-Lizana
Summary: The study examined the impact of copper oxidation state on the products formed in the continuous gas phase reactions of phenylacetylene hydrogenation and benzyl alcohol dehydrogenation over Cu/CeO₂ catalyst. It was found that the concentration of Cu-0 and Cu+ influenced the selectivity and turnover frequency of the products significantly. In the coupled process, full hydrogen utilization, exclusive benzaldehyde/styrene formation, and a greater styrene turnover frequency were achieved, showing the potential of sustainable hydrogen free hydrogenations using non-noble Cu catalysts.
JOURNAL OF CATALYSIS
(2021)
Article
Chemistry, Inorganic & Nuclear
Zhiqiang Hao, Junhua Zhang, Xiaoying Zhang, Zhihong Ma, Zhangang Han, Jin Lin, Guo-Liang Lu
Summary: Three new mononuclear copper complexes were obtained by treating Cu(OAc)(2).H2O with three different Schiff-base ligands. These complexes showed efficient catalytic activity in the oxidation of alcohols and water was the only by-product.
Article
Chemistry, Inorganic & Nuclear
Faizah S. Aljohani, Omran A. Omran, Eman A. Ahmed, Eida S. Al-Farraj, Elham F. Elkady, Arwa Alharbi, Nashwa M. El-Metwaly, Ibrahim Omar Barnawi, Ahmed M. Abu-Dief
Summary: A novel bis(1H-benzo[d]imidazol-2-yl)methanone (H2L) ligand and its metal chelates of Zinc (II), Nickel (II), Copper (II), and Iron (III) were synthesized. The metal chelates demonstrated better biomedical efficiency than the ligand alone. The most effective agent, BIMCu, showed outstanding antiproliferative efficacy against cancer cells.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Mohamed Shaker S. Adam, Obadah S. Abdel-Rahman, Mohamed M. Makhlouf
Summary: Divalent para-magnetic copper(II) and iron(II) chelates of Schiffbase isatin hydrazone derivative are synthesized and characterized. CuLONOCl and Fe(LONO)(2) exhibit distorted square planar and octahedral structures, respectively. Both chelates show catalytic activity in the oxidation of benzyl alcohol, with CuLONOCl displaying higher yields of benzaldehyde and Fe(LONO)(2) exhibiting less catalytic action. CuLONOCl also demonstrates stronger antimicrobial and anticancer effects compared to Fe(LONO)(2). The interaction of these chelates with ctDNA is studied spectroscopically.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Physical
Abdulrhman A. A. Al-Shamry, Mai M. M. Khalaf, Hany M. Abd El-Lateef, Tarek A. A. Yousef, Gehad G. G. Mohamed, Kariman M. Kamal El-Deen, Mohamed Gouda, Ahmed M. M. Abu-Dief
Summary: A Schiff base ligand was synthesized through the condensation of isatin and aniline, and a series of metal complexes derived from the ligand were characterized. The metal complexes exhibited different geometries and thermal decomposition behaviors. The metal complexes showed stronger antibacterial properties and anticancer activities compared to the ligand alone. A DFT investigation provided information on the electronic features of the ligand and its metal complexes. The drug-likeness and ADME characteristics of the compounds were also calculated.
Article
Chemistry, Physical
Mohamed Ali Ibrahim Al-Gaber, Hany M. Abd El-Lateef, Mai M. Khalaf, Saad Shaaban, Mohamed Shawky, Gehad G. Mohamed, Aly Abdou, Mohamed Gouda, Ahmed M. Abu-Dief
Summary: A new heterocyclic azo dye ligand (L) was synthesized and coordinated with various metal ions to form complexes. The structures of the complexes were determined using multiple techniques. The ligand exhibited tri-dentate behavior and coordinated to the metal ions through multiple functional groups. The complexes showed good antimicrobial activity and potential for future study.
Article
Nanoscience & Nanotechnology
Ahmed M. Abu-Dief, Mosa Alsehli, Aziz Awaad
Summary: Surface coating of silica nanoparticles (SiNPs) with polyethylene glycol (PEG) can control their biodistribution and in vivo interaction. SiNPs with higher coating density of PEG showed prolonged circulation time in the blood compared to SiNPs with lower coating density of PEG or amine surface coating. PEG surface coating plays an important role in controlling the biodistribution and immunogenicity of SiNPs-based drug delivery systems.
APPLIED NANOSCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Meshal Alzaid, W. S. Mohamed, Rakan Alanazi, Ibrahim Hotan Alsohaimi, Hassan M. A. Hassan, N. M. A. Hadia, Mohammed Ezzeldien, M. R. El-Aassar, Ahmed M. Abu-Dief
Summary: In this study, (Y2O3) x (CdO) 1-x mixed oxides nanocomposites with different Y2O3 loadings were synthesized via a precipitation approach. The NCs showed crystalline and cubic-phase purity, and their crystallite size ranged from 45 to 52 nm. By adding Y2O3, the optical band gap of the NCs decreased, and the surface area and pore volume increased, indicating increased porosity. UV-vis spectroscopy revealed that Y2O3 loading significantly improved the photocatalytic activities of the NCs, and the (Y2O3) 0.2 (CdO) 0.8 NCs showed the highest photodegradation efficiency for methylene blue under solar irradiation.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Engineering, Chemical
Mohamed Shaker S. Adam, Hany Elsawy, Azza Sedky, Mohamed M. Makhlouf, Amel Taha
Summary: Based on the coordination ability of dihydrazone derivatives, new homo dinuclear complexes (CuLss and ZrOLss) were synthesized using diisatin succinyldihydrazone ligand (H(2)Lss). These complexes exhibited good catalytic performance in the oxidation of benzyl alcohol and showed significant antimicrobial and anticancer activities. CuLss displayed stronger interaction with ctDNA compared to ZrOLss. Overall, CuLss and ZrOLss demonstrated higher reactivity and interaction potential than their precursor ligand H(2)Lss.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2023)
Article
Chemistry, Multidisciplinary
Hany M. Abd El-Lateef, Wafaa M. Abd El-Monem Nasr, Mai M. Khalaf, Adila E. Mohamed, Mohamed Nageeb Rashed, Mohamed Shaker S. Adam
Summary: In this study, three different Schiff base derivatives were successfully synthesized, and their corrosion inhibition effect on C1018 steel in CO2-saturated 3.5% NaCl solution was investigated. The synthesized Schiff base molecules showed outstanding corrosion inhibition effect on carbon steel at low concentrations. SEM/EDX analysis confirmed the formation of an adsorbed inhibitor film on the metal surface. Computational inspections correlated well with the experimental findings. The outcomes could have implications in assessing the efficiency of inhibiting agents in the gas and oil industry.
Article
Multidisciplinary Sciences
M. Alahmadi, Wael. H. Alsaedi, W. S. Mohamed, Hassan M. A. Hassan, Mohammed Ezzeldien, Ahmed M. Abu-Dief
Summary: Here, we demonstrate the sample and low-cost hydrothermal synthesis of a nanocomposite of Bi2O3/MoSe2 for hybrid photocatalyst. The structure of the synthesized samples was characterized using various techniques, and the Bi2O3/MoSe2 nanocomposite showed enhanced photocatalytic activity due to its high crystallinity, surface area, and small particle size. The results indicate that the Bi2O3/MoSe2 sample exhibited the highest photocatalytic degradation efficiency for the disintegration of methylene blue under visible illumination.
JOURNAL OF TAIBAH UNIVERSITY FOR SCIENCE
(2023)
Article
Nanoscience & Nanotechnology
Mohamed Shaker S. Adam, Amel Taha, Mostafa M. M. Mostafa, Farman Ullah, Mohamed M. M. Makhlouf
Summary: The industrialization of organic compound oxidation processes can be accelerated by synthesizing a monometallic dioxomolybdenum(VI) bis-Schiff base complex (MoO2L2) through coordination of 4-hydroxyiminophenol ligand (HL) with cis-MoO2 (2+) ion. A heterogeneous catalyst (MoO2L2@ZnO-TiO2) was prepared by immobilization of MoO2L2 on the surface of ZnO-TiO2 nanostructured particles. Both catalysts showed high catalytic potential and recyclability. Rating: 8/10.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Physical
Ahmed M. Abu-Dief, Rafat M. El-Khatib, Tarek El-Dabea, Aly Abdou, Faizah S. Aljohani, Eida S. Al-Farraj, Ibrahim Omar Barnawi, Mahmoud Abd El Aleem Ali Ali El-Remaily
Summary: New medicinally active chelates were synthesized from Cu(II), VO(II), Ag(I), and Pd(II) ions using the N-(1H-Benzoimidazol-2-yl)-guanidine (BIG) ligand. The compounds were characterized using various techniques and theoretical studies were conducted to identify important features. The chelates exhibited good stability in solution and showed promising biological activities, including antimicrobial, antioxidant, and anticancer properties. These results suggest that the studied chelates have the potential to be used as bioactive agents.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Mahmoud Abd El Aleem Ali Ali El-Remaily, O. Elhady, Aly Abdou, Dalal Alhashmialameer, Thomas Nady A. Eskander, Ahmed M. Abu-Dief
Summary: We established new imidazole complexes using Pd2+, Fe3+, and Ni2+ ions, with the exception of the Pd (II) chelate (BIL-Pd) which has a square-planer configuration, the octahedral geometry was recommended for the other examined complexes. The condensation reaction of three components resulted in the synthesis of 5-amino-2-oxo-3,7-dihydro2H-pyrano[2,3-d]thiazole-6-carbonitrile derivatives under controlled and environmentally friendly conditions. The BIL-Pd complex showed effectiveness as a recyclable and promising heterogeneous solid catalyst.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Physics, Multidisciplinary
Eida S. Al-Farraj, M. Alahmadi, W. S. Mohamed, Wael H. Alsaedi, Ahmed M. Abu-Dief
Summary: Nanoparticles of VSe2, Cu2Se and VSe2@Cu2Se were synthesized using a one-pot hydrothermal method, demonstrating their potential as chemotherapeutic agents. Structural and microstructural analysis showed that the nanoparticles have a pure crystalline cubic structure, with varying crystallite sizes depending on the composition. Antibacterial and anticancer experiments revealed that the nanocomposite exhibited a synergistic effect, with VSe2/Cu2Se showing the highest antibacterial efficacy against both Gram-positive and Gram-negative bacteria.
Article
Chemistry, Physical
Mohamed Shaker S. Adam, Ahmed Khalil, Amel Taha, Mostafa M. Mostafa, Mohamed M. Makhlouf, Hatem A. Mahmoud
Summary: Oxovanadium (IV) bis-Schiff base complex was synthesized through a simple complexation between 2-hydroxy-Schiff base ligand (HL) and VO2+ ion, resulting in a mononuclear VOL2 complex with a square pyramidal geometry. The structure of HL and VOL2 complex was determined using spectroscopic techniques and elemental analysis. The VOL2 complex was successfully coated on TiO2-ZnO nanoparticles, forming a nanocomposite of TiO2-ZnO@VOL2. The surface morphology and internal structure of TiO2-ZnO@VOL2 nanocomposites were studied using various characterization techniques. The catalytic effectiveness of VOL2 and TiO2-ZnO@VOL2 catalysts was evaluated in the oxygenation reactions of benzyl alcohol, where both catalysts exhibited significant catalytic activity. The difference in catalytic reactivity was attributed to the heterogeneity and the effect of coated TiO2-ZnO nanoparticles on the VOL2 catalytic potential. The kinetic parameters of the redox protocols for both catalysts were determined, and the catalytic system was found to be effective for other alcohols as well.
SURFACES AND INTERFACES
(2023)
Article
Chemistry, Inorganic & Nuclear
Ahmed M. Abu-Dief, Musa A. Said, O. Elhady, Seraj Alzahrani, Faizah S. Aljohani, Thomas Nady A. Eskander, Mahmoud Abd El Aleem Ali Ali El-Remaily
Summary: Three novel complexes were synthesized by reacting BSP benzothiazol-2-yl-(4,6-dimethyl-1H-pyrimidin-2-ylidene)-amine with Fe3+, Ni2+, and Pd2+. The structural details of the ligand and metal complexes were characterized using various experimental techniques and theoretical calculations. The complexes exhibited antibacterial and antioxidant activities, and showed promising cytotoxicity against cancer cells.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
