Modification of daunorubicin-GnRH-III bioconjugates with oligoethylene glycol derivatives to improve solubility and bioavailability for targeted cancer chemotherapy

Synthesis, enzymatic stability and in vitro cytostatic effect of Daunorubicin-GnRH-III derivative dimers

(2013) Verena Natalie Schreier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anticancer Therapy by Tumor Vessel Infarction with Polyethylene Glycol Conjugated Retargeted Tissue Factor

(2013) Christian Schwöppe et al.   JOURNAL OF MEDICINAL CHEMISTRY

LHRH-Targeted Nanogels as a Delivery System for Cisplatin to Ovarian Cancer

(2013) Natalia V. Nukolova et al.   MOLECULAR PHARMACEUTICS

PEGylation enables the specific tumor accumulation of a peptide identified by phage display

(2013) Walter Mier et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate

(2012) Ulrike Leurs et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Enhanced cellular uptake and in vitro antitumor activity of short-chain fatty acid acylated daunorubicin–GnRH-III bioconjugates

(2012) Rózsa Hegedüs et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In-vivo antitumour effect of daunorubicin–GnRH-III derivative conjugates on colon carcinoma-bearing mice

(2011) Marilena Manea et al.   ANTI-CANCER DRUGS

Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4

(2011) Marilena Manea et al.   BIOCONJUGATE CHEMISTRY

Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety

(2011) Ulrike Leurs et al.   BIOPOLYMERS

Anthracycline-GnRH derivative bioconjugates with different linkages: Synthesis, in vitro drug release and cytostatic effect

(2011) Pascal Schlage et al.   JOURNAL OF CONTROLLED RELEASE

In vitro degradation and antitumor activity of oxime bond-linked daunorubicin–GnRH-III bioconjugates and DNA-binding properties of daunorubicin–amino acid metabolites

(2010) Erika Orbán et al.   AMINO ACIDS

Efficient synthesis of an (aminooxy) acetylated-somatostatin derivative using (aminooxy)acetic acid as a ‘carbonyl capture’ reagent

(2010) Gábor Mezö et al.   JOURNAL OF PEPTIDE SCIENCE

Peptide vaccine candidates against classical swine fever virus: T cell and neutralizing antibody responses of dendrimers displaying E2 and NS2-3 epitopes

(2010) Marta Monsó et al.   JOURNAL OF PEPTIDE SCIENCE

Development of an Oxime Bond Containing Daunorubicin-Gonadotropin-Releasing Hormone-III Conjugate as a Potential Anticancer Drug

(2009) Ildikó Szabó et al.   BIOCONJUGATE CHEMISTRY

New biotin derivatives for labeling and solubilizing IgG peptides

(2009) Ádám Bartos et al.   BIOPOLYMERS

Receptor-mediated tumor targeting based on peptide hormones

(2009) Gábor Mező et al.   Expert Opinion on Drug Delivery

Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre

(2009) Daniel Scharlau et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

New Derivatives of GnRH as Potential Anticancer Therapeutic Agents

(2008) Gabor Mezo et al.   CURRENT MEDICINAL CHEMISTRY

Recent Trends in Targeted Anticancer Prodrug and Conjugate Design

(2008) Yashveer Singh et al.   CURRENT MEDICINAL CHEMISTRY

Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms

(2007) Emilio Lecona et al.   BIOCHEMICAL JOURNAL