Atypical ubiquitin ligase RNF31: the nuclear factor modulator in breast cancer progression

Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma

(2016) Yibin Yang et al.   CANCER CELL

Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia

(2015) Bertrand Boisson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Subtype-Specific Modulation of Estrogen Receptor–Coactivator Interaction by Phosphorylation

(2014) Inga M. Tharun et al.   ACS Chemical Biology

E3 Ubiquitin Ligase HOIP Attenuates Apoptotic Cell Death Induced by Cisplatin

(2014) Craig MacKay et al.   CANCER RESEARCH

Targeting the NFκB Signaling Pathways for Breast Cancer Prevention and Therapy

(2014) Wei Wang et al.   CURRENT MEDICINAL CHEMISTRY

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Nonenzymatic Polyubiquitination of Expressed Proteins

(2014) Hosahalli P. Hemantha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Binding of OTULIN to the PUB Domain of HOIP Controls NF-κB Signaling

(2014) Veronique Schaeffer et al.   MOLECULAR CELL

The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation

(2014) J Zhu et al.   ONCOGENE

Germline Polymorphisms in RNF31 Regulate Linear Ubiquitination and Oncogenic Signaling

(2014) P. Grumati et al.   Cancer Discovery

HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death

(2014) Nieves Peltzer et al.   Cell Reports

Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2013) E. Senkus et al.   ANNALS OF ONCOLOGY

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells

(2013) Yoshiteru Sasaki et al.   EMBO JOURNAL

Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP

(2013) Benjamin Stieglitz et al.   NATURE

Knockdown of RNF2 induces apoptosis by regulating MDM2 and p53 stability

(2013) W Wen et al.   ONCOGENE

Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen

(2013) C Donley et al.   ONCOGENE

Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells

(2013) M F Kendellen et al.   ONCOGENE

Inhibition of triple-negative breast cancer models by combinations of antibodies to EGFR

(2013) D. A. Ferraro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transcriptional activity of co-activator AIB1 is regulated by the SUMO E3 Ligase PIAS1

(2012) Shujing Li et al.   BIOLOGY OF THE CELL

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension

(2012) Judith J Smit et al.   EMBO JOURNAL

HECT and RING finger families of E3 ubiquitin ligases at a glance

(2012) M. B. Metzger et al.   JOURNAL OF CELL SCIENCE

Cellular strategies for making monoubiquitin signals

(2011) Harish N. Ramanathan et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

p53 regulation by ubiquitin

(2011) Christopher L. Brooks et al.   FEBS LETTERS

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

(2011) Fumiyo Ikeda et al.   NATURE

The impact of acetylation and deacetylation on the p53 pathway

(2011) Christopher L. Brooks et al.   Protein & Cell

RBCK1 Drives Breast Cancer Cell Proliferation by Promoting Transcription of Estrogen Receptor   and Cyclin B1

(2010) N. Gustafsson et al.   CANCER RESEARCH

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

(2010) J. J. Manfredi   GENES & DEVELOPMENT

Smad Ubiquitylation Regulatory Factor 1/2 (Smurf1/2) Promotes p53 Degradation by Stabilizing the E3 Ligase MDM2

(2010) Jing Nie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HOIL-1L Interacting Protein (HOIP) as an NF-κB Regulating Component of the CD40 Signaling Complex

(2010) Bruce S. Hostager et al.   PLoS One

The role of BRCA1 in DNA damage response

(2010) Jiaxue Wu et al.   Protein & Cell

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Targeting p53 for enhanced radio- and chemo-sensitivity

(2009) Chao Lu et al.   APOPTOSIS

Linear polyubiquitination: a new regulator of NF-κB activation

(2009) Kazuhiro Iwai et al.   EMBO REPORTS

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Re: Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer

(2009) S. J. Howell et al.   JNCI-Journal of the National Cancer Institute

E3 Ubiquitin Ligase RNF31 Cooperates with DAX-1 in Transcriptional Repression of Steroidogenesis

(2009) A. Ehrlund et al.   MOLECULAR AND CELLULAR BIOLOGY

Estrogen Receptor Alpha Represses Transcription of Early Target Genes via p300 and CtBP1

(2009) F. Stossi et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterization of Polyubiquitin Chain Structure by Middle-down Mass Spectrometry

(2008) Ping Xu et al.   ANALYTICAL CHEMISTRY

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

(2008) Francesca Bernassola et al.   CANCER CELL