Fibrin as a Multipurpose Physiological Platform for Bone Tissue Engineering and Targeted Delivery of Bioactive Compounds

Fibrin glue as a local drug-delivery system for bacteriophage PA5

(2019) Evgenii Rubalskii et al.   Scientific Reports

The Application of microRNAs in Biomaterial Scaffold‐Based Therapies for Bone Tissue Engineering

(2019) Marco A. Arriaga et al.   Biotechnology Journal

Fibrin-VLDL Receptor-Dependent Pathway Promotes Leukocyte Transmigration by Inhibiting Src Kinase Fyn and is a Target for Fibrin β15-42 Peptide

(2019) Sergiy Yakovlev et al.   THROMBOSIS AND HAEMOSTASIS

Enhancing clot properties through fibrin-specific self-cross-linked PEG side-chain microgels

(2018) Nicole Welsch et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Delivery systems of local anesthetics in bone surgery: are they efficient and safe?

(2018) Manon Dupleichs et al.   DRUG DISCOVERY TODAY

Pain Management After Bone Reconstruction Surgery Using an Analgesic Bone Cement: A Functional Noninvasive In Vivo Study Using Gait Analysis

(2018) Manon Dupleichs et al.   JOURNAL OF PAIN

Effect of fibrinogen, fibrin, and fibrin degradation products on transendothelial migration of leukocytes

(2018) Sergiy Yakovlev et al.   THROMBOSIS RESEARCH

Biomaterials for the Delivery of Growth Factors and Other Therapeutic Agents in Tissue Engineering Approaches to Bone Regeneration

(2018) Christine J. Kowalczewski et al.   Frontiers in Pharmacology

Platelet-rich fibrin in oral surgical procedures: a systematic review and meta-analysis

(2018) J.V.d.S. Canellas et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

The effect of a fibrin sealant on knee function after total knee replacement surgery. Results from the FIRST trial. A multicenter randomized controlled trial

(2018) Wiebe C. Verra et al.   PLoS One

The 3 R’s for Platelet-Rich Fibrin: A “Super” Tri-Dimensional Biomaterial for Contemporary Naturally-Guided Oro-Maxillo-Facial Soft and Hard Tissue Repair, Reconstruction and Regeneration

(2018) Consuelo Zumarán et al.   Materials

The proper timing of second-stage revision in treating periprosthetic knee infection: reliable indicators and risk factors

(2018) Jun Fu et al.   Journal of Orthopaedic Surgery and Research

Model predictions of deformation, embolization and permeability of partially obstructive blood clots under variable shear flow

(2017) Shixin Xu et al.   Journal of the Royal Society Interface

A doxycycline inducible, adenoviral bone morphogenetic protein-2 gene delivery system to bone

(2017) Jennifer J. Bara et al.   Journal of Tissue Engineering and Regenerative Medicine

Fibrin mechanical properties and their structural origins

(2017) Rustem I. Litvinov et al.   MATRIX BIOLOGY

Compression-induced structural and mechanical changes of fibrin-collagen composites

(2017) O.V. Kim et al.   MATRIX BIOLOGY

Effects of an injectable platelet-rich fibrin on osteoblast behavior and bone tissue formation in comparison to platelet-rich plasma

(2017) Xuzhu Wang et al.   PLATELETS

The impact of the centrifuge characteristics and centrifugation protocols on the cells, growth factors, and fibrin architecture of a leukocyte- and platelet-rich fibrin (L-PRF) clot and membrane

(2017) David M. Dohan Ehrenfest et al.   PLATELETS

Molecular and Physical Mechanisms of Fibrinolysis and Thrombolysis from Mathematical Modeling and Experiments

(2017) Brittany E. Bannish et al.   Scientific Reports

Clot-entrapped blood cells in synergy with human mesenchymal stem cells create a pro-angiogenic healing response

(2017) Melanie A. Burkhardt et al.   Biomaterials Science

RGD and BMP-2 mimetic peptide crosstalk enhances osteogenic commitment of human bone marrow stem cells

(2016) I. Bilem et al.   Acta Biomaterialia

Nano-fibrin stabilized CaSO 4 crystals incorporated injectable chitin composite hydrogel for enhanced angiogenesis & osteogenesis

(2016) R. Arun Kumar et al.   CARBOHYDRATE POLYMERS

Mesenchymal stem cell growth on and mechanical properties of fibrin-based biomimetic bone scaffolds

(2016) Chase S. Linsley et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Recent Developments in the Biology of Fracture Repair

(2016) Francois N. K. Kwong et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Extracellular signaling molecules to promote fracture healing and bone regeneration

(2015) K.D. Hankenson et al.   ADVANCED DRUG DELIVERY REVIEWS

Biomimetic supramolecular designs for the controlled release of growth factors in bone regeneration

(2015) Helena S. Azevedo et al.   ADVANCED DRUG DELIVERY REVIEWS

Foam-like compression behavior of fibrin networks

(2015) Oleg V. Kim et al.   Biomechanics and Modeling in Mechanobiology

Antimicrobial resistance: A global emerging threat to public health systems

(2015) Maurizio Ferri et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Grading of osteoarthritic cartilage: Correlations between histology and biomechanics

(2015) Clark T. Hung et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Osteogenic/Angiogenic Dual Growth Factor Delivery Microcapsules for Regeneration of Vascularized Bone Tissue

(2015) Ramesh Subbiah et al.   Advanced Healthcare Materials

Engineering personalized neural tissue by combining induced pluripotent stem cells with fibrin scaffolds

(2015) Amy Montgomery et al.   Biomaterials Science

Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors

(2014) Olaia F. Vila et al.   Acta Biomaterialia

Structural basis for the nonlinear mechanics of fibrin networks under compression

(2014) Oleg V. Kim et al.   BIOMATERIALS

Optimal condition of heparin-conjugated fibrin with bone morphogenetic protein-2 for spinal fusion in a rabbit model

(2014) Jae-Young Hong et al.   CYTOTHERAPY

Therapeutic strategies for treating osteolytic bone metastases

(2014) Elise Verron et al.   DRUG DISCOVERY TODAY

Cell culture in autologous fibrin scaffolds for applications in tissue engineering

(2014) Pilar de la Puente et al.   EXPERIMENTAL CELL RESEARCH

Improvement in angiogenesis and osteogenesis with modified cannulated screws combined with VEGF/PLGA/fibrin glue in femoral neck fractures

(2014) Licheng Zhang et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Fracture healing: mechanisms and interventions

(2014) Thomas A. Einhorn et al.   Nature Reviews Rheumatology

Fibrinogen and factor XIII at the intersection of coagulation, fibrinolysis and inflammation

(2014) Berthold Hoppe   THROMBOSIS AND HAEMOSTASIS

Comprehensive evaluation of fibrin glue as a local drug-delivery system—efficacy and safety of sustained release of vancomycin by fibrin glue against local methicillin-resistant Staphylococcus aureus infection

(2013) Shinichi Ozaki et al.   JOURNAL OF ARTIFICIAL ORGANS

High-Dose rhBMP-2 for Adults: Major and Minor Complications

(2013) Addisu Mesfin et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

A comparative study of the regenerative effect of sinus bone grafting with platelet-rich fibrin-mixed Bio-Oss® and commercial fibrin-mixed Bio-Oss®: An experimental study

(2013) Feng Xuan et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

The Effect of Fibrinogen, Collagen Type I, and Fibronectin on Mesenchymal Stem Cell Growth and Differentiation into Osteoblasts

(2013) Chase Linsley et al.   TISSUE ENGINEERING PART A

Controlling the biological function of calcium phosphate bone substitutes with drugs

(2012) E. Verron et al.   Acta Biomaterialia

The optimal carrier for BMP-2: a comparison of collagen versus fibrin matrix

(2012) Sebastian Schützenberger et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

The effects of the modulation of the fibronectin-binding capacity of fibrin by thrombin on osteoblast differentiation

(2012) Joung-Hwan Oh et al.   BIOMATERIALS

Culture on fibrin matrices maintains the colony-forming capacity and osteoblastic differentiation of mesenchymal stem cells

(2012) Helen Colley et al.   Biomedical Materials

Hydrogels for protein delivery in tissue engineering

(2012) Roberta Censi et al.   JOURNAL OF CONTROLLED RELEASE

Fibrin nanoconstructs: a novel processing method and their use as controlled delivery agents

(2012) G Praveen et al.   NANOTECHNOLOGY

Evaluation of bone regeneration using the rat critical size calvarial defect

(2012) Patrick P Spicer et al.   Nature Protocols

Preparation of 3D Fibrin Scaffolds for Stem Cell Culture Applications

(2012) Kathleen Kolehmainen et al.   Jove-Journal of Visualized Experiments

Bioengineering of dental stem cells in a PEGylated fibrin gel

(2011) Kerstin M Galler et al.   Regenerative Medicine

Hyaline Cartilage Regeneration by Combined Therapy of Microfracture and Long-Term Bone Morphogenetic Protein-2 Delivery

(2011) Hee Seok Yang et al.   TISSUE ENGINEERING PART A

Supplementation of fibrin gels with sodium chloride enhances physical properties and ensuing osteogenic response

(2010) H.E. Davis et al.   Acta Biomaterialia

A comparison of the mechanical, kinetic, and biochemical properties of fibrin clots formed with two different fibrin sealants

(2010) William L Hickerson et al.   BLOOD COAGULATION & FIBRINOLYSIS

Phage Therapy in Clinical Practice: Treatment of Human Infections

(2010) Elizabeth Kutter et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Calcium phosphate biomaterials as bone drug delivery systems: a review

(2010) Elise Verron et al.   DRUG DISCOVERY TODAY

Analgesic properties of calcium phosphate apatite loaded with bupivacaine on postoperative pain

(2010) Elise Verron et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

(2010) K. Lee et al.   Journal of the Royal Society Interface

Proliferation of Human Keratinocytes and Cocultured Human Keratinocytes and Fibroblasts in Three-Dimensional Fibrin Constructs

(2010) Nadjah Sese et al.   TISSUE ENGINEERING PART A

Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration

(2009) Diederik H.R. Kempen et al.   BIOMATERIALS

Controlled release of substances bound to fibrin-anchors or of DNA

(2009) T. J. Morton et al.   DRUG DELIVERY

Fibrin hydrogels for non-viral vector delivery in vitro

(2009) Anne des Rieux et al.   JOURNAL OF CONTROLLED RELEASE

Effect of Sustained-Release Lidocaine on Reduction of Pain After Subpectoral Breast Augmentation

(2009) Xiao Zhibo et al.   Aesthetic Surgery Journal

The Use of Phages for the Removal of Infectious Biofilms

(2008) J. Azeredo et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Liposomes/Chitosan Scaffold/Human Fibrin Gel Composite Systems for Delivering Hydrophilic Drugs—Release Behaviors of TirofibanIn Vitro

(2008) Shoi-Shen Wang et al.   DRUG DELIVERY

Fibrin scaffold promotes adenoviral gene transfer and controlled vector delivery

(2008) Ailish Breen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Fibrin gels and their clinical and bioengineering applications

(2008) P. A Janmey et al.   Journal of the Royal Society Interface

Large-scale preparation of thrombin from human plasma

(2008) Peter Aizawa et al.   THROMBOSIS RESEARCH

Platelet-Osteosarcoma Cell Interaction is Mediated Through a Specific Fibrinogen-Binding Sequence Located Within the N-Terminal Domain of Thrombospondin 1

(2006) Carole Voland et al.   JOURNAL OF BONE AND MINERAL RESEARCH