Progesterone receptor blockade in human breast cancer cells decreases cell cycle progression through G2/M by repressing G2/M genes

The unique transcriptional response produced by concurrent estrogen and progesterone treatment in breast cancer cells results in upregulation of growth factor pathways and switching from a Luminal A to a Basal-like subtype

(2015) Eleanor F. Need et al.   BMC CANCER

Progesterone receptor modulates ERα action in breast cancer

(2015) Hisham Mohammed et al.   NATURE

Molecular determinants of context-dependent progesterone receptor action in breast cancer

(2014) Christy R Hagan et al.   BMC Medicine

The CHR site: definition and genome-wide identification of a cell cycle transcriptional element

(2014) Gerd A. Müller et al.   NUCLEIC ACIDS RESEARCH

Lentiviral Vector-Mediated siRNA Knockdown of c-MYC: Cell Growth Inhibition and Cell Cycle Arrest at G2/M Phase in Jijoye Cells

(2013) Aiqin Song et al.   BIOCHEMICAL GENETICS

Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial

(2013) Jack Cuzick et al.   LANCET

More help than hindrance

(2013) Cecilia Ballaré et al.   Nucleus

Estrogen Receptor Alpha Mediates Progestin-Induced Mammary Tumor Growth by Interacting with Progesterone Receptors at the Cyclin D1/MYC Promoters

(2012) S. Giulianelli et al.   CANCER RESEARCH

Efficacy and mechanism of action of Proellex, an antiprogestin in aromatase overexpressing and Letrozole resistant T47D breast cancer cells

(2012) Akash Gupta et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Nucleosome-Driven Transcription Factor Binding and Gene Regulation

(2012) Cecilia Ballaré et al.   MOLECULAR CELL

The biology of progesterone receptor in the normal mammary gland and in breast cancer

(2011) Alison E. Obr et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

New Insights into Checkpoint Kinase 1 in the DNA Damage Response Signaling Network

(2010) Y. Dai et al.   CLINICAL CANCER RESEARCH

Multimodal Regulation of E2F1 Gene Expression by Progestins

(2010) H. E. Wade et al.   MOLECULAR AND CELLULAR BIOLOGY

Progesterone induces adult mammary stem cell expansion

(2010) Purna A. Joshi et al.   NATURE

The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription

(2009) Gerd A. Müller et al.   FEBS Journal

Targeting the BAF57 SWI/SNF Subunit in Prostate Cancer: A Novel Platform to Control Androgen Receptor Activity

(2008) K. A. Link et al.   CANCER RESEARCH

Progesterone Receptor Rapid Signaling Mediates Serine 345 Phosphorylation and Tethering to Specificity Protein 1 Transcription Factors

(2008) Emily J. Faivre et al.   MOLECULAR ENDOCRINOLOGY