Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle

Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart

(2018) Guglielmina Chimienti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders

(2018) Anna Picca et al.   REJUVENATION RESEARCH

The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) randomized controlled trial: Case finding, screening and characteristics of eligible participants

(2018) Emanuele Marzetti et al.   EXPERIMENTAL GERONTOLOGY

SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis

(2017) Renea P. Jablonski et al.   FASEB JOURNAL

Fueling Inflamm-Aging through Mitochondrial Dysfunction: Mechanisms and Molecular Targets

(2017) Anna Picca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

“What makes some rats live so long?” The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content

(2016) Anna Picca et al.   EXPERIMENTAL GERONTOLOGY

Systemic inflammation, body composition, and physical performance in old community-dwellers

(2016) Riccardo Calvani et al.   Journal of Cachexia Sarcopenia and Muscle

Iron –sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery

(2015) Nunziata Maio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults

(2014) Marco Pahor et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mitochondrial Involvement and Impact in Aging Skeletal Muscle

(2014) Russell T. Hepple   Frontiers in Aging Neuroscience

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age

(2013) B. J. McCranor et al.   HAEMATOLOGICA

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

(2012) Anna-Maria Joseph et al.   AGING CELL

Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy

(2012) Riccardo Calvani et al.   BIOLOGICAL CHEMISTRY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Skeletal Muscle Apoptotic Signaling Predicts Thigh Muscle Volume and Gait Speed in Community-Dwelling Older Persons: An Exploratory Study

(2012) Emanuele Marzetti et al.   PLoS One

Hepatocyte-like cells differentiated from human induced pluripotent stem cells: Relevance to cellular therapies

(2012) Yue Yu et al.   Stem Cell Research

Erythropoietin, GDF15, IL6, hepcidin and testosterone levels in a large cohort of elderly individuals with anaemia of known and unknown cause

(2011) Jill Waalen et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Long-term perturbation of muscle iron homeostasis following hindlimb suspension in old rats is associated with high levels of oxidative stress and impaired recovery from atrophy

(2011) Jinze Xu et al.   EXPERIMENTAL GERONTOLOGY

Age-related differences in lower extremity tissue compartments and associations with physical function in older adults

(2011) Thomas W. Buford et al.   EXPERIMENTAL GERONTOLOGY

The association between low-grade inflammation, iron status and nucleic acid oxidation in the elderly

(2011) Kasper Broedbaek et al.   FREE RADICAL RESEARCH

Gait Speed and Survival in Older Adults

(2011) Stephanie Studenski   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hepcidin and Disorders of Iron Metabolism

(2010) Tomas Ganz et al.   Annual Review of Medicine

Proinflammatory state, hepcidin, and anemia in older persons

(2010) L. Ferrucci et al.   BLOOD

The emerging role of iron dyshomeostasis in the mitochondrial decay of aging

(2010) Jinze Xu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mammalian Zinc Transporters: Nutritional and Physiologic Regulation

(2009) Louis A. Lichten et al.   Annual Review of Nutrition

Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-γ expression in activated human T cells

(2009) Tolunay B. Aydemir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Use of the Short Physical Performance Battery Score to Predict Loss of Ability to Walk 400 Meters: Analysis From the InCHIANTI Study

(2009) S. Vasunilashorn et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction

(2009) Emanuele Marzetti et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mitochondrial iron accumulation with age and functional consequences

(2008) Arnold Y.  Seo et al.   AGING CELL

Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy

(2008) Tim Hofer et al.   EXPERIMENTAL GERONTOLOGY

Body iron metabolism and pathophysiology of iron overload

(2008) Yutaka Kohgo et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

The Hereditary Hemochromatosis Protein, HFE, Inhibits Iron Uptake via Down-regulation of Zip14 in HepG2 Cells

(2008) Junwei Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased serum ferritin levels in amyotrophic lateral sclerosis (ALS) patients

(2008) E. F. Goodall et al.   JOURNAL OF NEUROLOGY

Iron Accumulation with Age, Oxidative Stress and Functional Decline

(2008) Jinze Xu et al.   PLoS One

Unexplained Anemia in the Elderly

(2008) Sasan Makipour et al.   SEMINARS IN HEMATOLOGY