Structure and Function of the Nuclear Receptor Superfamily and Current Targeted Therapies of Prostate Cancer

Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer

(2019) Karim Fizazi et al.   NEW ENGLAND JOURNAL OF MEDICINE

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

(2019) Laura Cato et al.   CANCER CELL

Profiling Prostate Cancer Therapeutic Resistance

(2018) Cameron Wade et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting Transcription Factors for Cancer Treatment

(2018) Mélanie Lambert et al.   MOLECULES

Metastatic Prostate Cancer

(2018) Oliver Sartor et al.   NEW ENGLAND JOURNAL OF MEDICINE

STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers

(2018) Dayson Moreira et al.   CLINICAL CANCER RESEARCH

Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer

(2016) Y. C. Yang et al.   CLINICAL CANCER RESEARCH

c-JUN Dimerization Protein 2 (JDP2) Is a Transcriptional Repressor of Follicle-stimulating Hormone β (FSHβ) and Is Required for Preventing Premature Reproductive Senescence in Female Mice

(2016) Carrie R. Jonak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Effects of PI3K and Dual PI3K/mTOR Inhibition in Rat Prolactin-Secreting Pituitary Tumors

(2016) Marie Chanal et al.   MOLECULAR CANCER THERAPEUTICS

Enzalutamide: targeting the androgen signalling pathway in metastatic castration-resistant prostate cancer

(2015) Jack Schalken et al.   BJU INTERNATIONAL

Understanding the Mechanisms of Androgen Deprivation Resistance in Prostate Cancer at the Molecular Level

(2015) Theodoros Karantanos et al.   EUROPEAN UROLOGY

Progesterone receptor expression during prostate cancer progression suggests a role of this receptor in stromal cell differentiation

(2015) Yue Yu et al.   PROSTATE

Prevalence of Prostate Cancer Clinical States and Mortality in the United States: Estimates Using a Dynamic Progression Model

(2015) Howard I. Scher et al.   PLoS One

Androgen receptor: structure, role in prostate cancer and drug discovery

(2014) MH Eileen Tan et al.   ACTA PHARMACOLOGICA SINICA

AEG-1 Regulates Retinoid X Receptor and Inhibits Retinoid Signaling

(2014) J. Srivastava et al.   CANCER RESEARCH

Unknown

(2014) Paraskevi Christoforou et al.   MOLECULAR MEDICINE

Prostate Stromal Cells Express the Progesterone Receptor to Control Cancer Cell Mobility

(2014) Yue Yu et al.   PLoS One

Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade

(2013) Vivek K. Arora et al.   CELL

Minireview: Dynamic Structures of Nuclear Hormone Receptors: New Promises and Challenges

(2013) S. Stoney Simons et al.   MOLECULAR ENDOCRINOLOGY

Overcoming mutation-based resistance to antiandrogens with rational drug design

(2013) Minna D Balbas et al.   eLife

Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer

(2012) R. Hu et al.   CANCER RESEARCH

Binding of the N-terminal Region of Coactivator TIF2 to the Intrinsically Disordered AF1 Domain of the Glucocorticoid Receptor Is Accompanied by Conformational Reorganizations

(2012) Shagufta H. Khan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Androgen receptor (AR) aberrations in castration-resistant prostate cancer

(2012) Kati K. Waltering et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer

(2012) Yasser Rehman et al.   Drug Design Development and Therapy

Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants

(2011) Elahe A. Mostaghel et al.   CLINICAL CANCER RESEARCH

Structural features discriminate androgen receptor N/C terminal and coactivator interactions

(2011) Emily B. Askew et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Structural and functional analysis of domains of the progesterone receptor

(2011) Krista K. Hill et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Abiraterone and Increased Survival in Metastatic Prostate Cancer

(2011) Johann S. de Bono et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural Overview of the Nuclear Receptor Superfamily: Insights into Physiology and Therapeutics

(2010) Pengxiang Huang et al.   Annual Review of Physiology

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

(2010) Shihua Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Methylation, a key step for nongenomic estrogen signaling in breast tumors

(2010) M. Le Romancer et al.   STEROIDS

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

(2009) S. H. Meijsing et al.   SCIENCE

Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

(2009) C. Tran et al.   SCIENCE

Stat3 Promotes Metastatic Progression of Prostate Cancer

(2008) Junaid Abdulghani et al.   AMERICAN JOURNAL OF PATHOLOGY

Consequences of poly-glutamine repeat length for the conformation and folding of the androgen receptor amino-terminal domain

(2008) Philippa Davies et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Steroidogenic Factor-1 (SF-1, Ad4BP, NR5A1) and Disorders of Testis Development

(2008) L. Lin et al.   Sexual Development