Epithelial Alarmins in Serum and Exhaled Breath in Patients with Idiopathic Pulmonary Fibrosis: A Prospective One-Year Follow-Up Cohort Study

IL-25 contributes to lung fibrosis by directly acting on alveolar epithelial cells and fibroblasts

(2019) Xuefeng Xu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Epithelial alarmin levels in exhaled breath condensate in patients with idiopathic pulmonary fibrosis: A pilot study

(2019) Sebastian Majewski et al.   Clinical Respiratory Journal

Comparative Study of IL-33 and IL-6 Levels in Different Respiratory Samples in Mild-to-Moderate Asthma and COPD

(2018) Katarzyna Gorska et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

An ST2-dependent role of bone marrow-derived group 2 innate lymphoid cells in pulmonary fibrosis

(2018) Yuyue Zhao et al.   JOURNAL OF PATHOLOGY

Idiopathic Pulmonary Fibrosis

(2018) David J. Lederer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pirfenidone suppresses bleomycin‑induced pulmonary fibrosis and periostin expression in rats

(2018) Xiaoxia Song et al.   Experimental and Therapeutic Medicine

Transcriptome profiling reveals the complexity of pirfenidone effects in IPF

(2018) Grazyna Kwapiszewska et al.   EUROPEAN RESPIRATORY JOURNAL

Histopathologic and Molecular Analysis of Idiopathic Pulmonary Fibrosis Lungs from Patients Treated with Pirfenidone or Nintedanib

(2018) Yingwei Zhang et al.   HISTOPATHOLOGY

Official ERS technical standards: Global Lung Function Initiative reference values for the carbon monoxide transfer factor for Caucasians

(2017) Sanja Stanojevic et al.   EUROPEAN RESPIRATORY JOURNAL

2017 ERS/ATS standards for single-breath carbon monoxide uptake in the lung

(2017) Brian L. Graham et al.   EUROPEAN RESPIRATORY JOURNAL

Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors

(2017) Miroslava Didiasova et al.   FASEB JOURNAL

Upregulation of interleukin-33 and thymic stromal lymphopoietin levels in the lungs of idiopathic pulmonary fibrosis

(2017) Jong-Uk Lee et al.   BMC Pulmonary Medicine

Increased Levels of Interleukin-33 and Thymic Stromal Lymphopoietin in Exhaled Breath Condensate in Chronic Bronchial Asthma

(2016) Joanna Glück et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

IL-33/ST2 pathway in a bleomycin-induced pulmonary fibrosis model

(2016) Jiao Xu et al.   Molecular Medicine Reports

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis

(2016) Kevin M. Vannella et al.   Science Translational Medicine

An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. An Update of the 2011 Clinical Practice Guideline

(2015) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epithelial Interleukin-25 Is a Key Mediator in Th2-High, Corticosteroid-Responsive Asthma

(2014) Dan Cheng et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Granulomas are a source of interleukin-33 expression in pulmonary and extrapulmonary sarcoidosis

(2014) Werner Kempf et al.   HUMAN PATHOLOGY

IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice

(2014) Dong Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

(2014) Talmadge E. King et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

(2014) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

The epithelium in idiopathic pulmonary fibrosis: breaking the barrier

(2014) Ana Camelo et al.   Frontiers in Pharmacology

Interleukin-33 Potentiates Bleomycin-Induced Lung Injury

(2013) Irina G. Luzina et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis

(2013) Alicia Usategui et al.   ANNALS OF THE RHEUMATIC DISEASES

Airway epithelial regulation of pulmonary immune homeostasis and inflammation

(2013) Teal S. Hallstrand et al.   CLINICAL IMMUNOLOGY

Evidence for a Functional Thymic Stromal Lymphopoietin Signaling Axis in Fibrotic Lung Disease

(2013) A. Datta et al.   JOURNAL OF IMMUNOLOGY

TH2, allergy and group 2 innate lymphoid cells

(2013) Paula Licona-Limón et al.   NATURE IMMUNOLOGY

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis

(2013) E. Hams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations

(2012) Philip H. Quanjer et al.   EUROPEAN RESPIRATORY JOURNAL

Exhaled Breath Condensate

(2012) Michael D. Davis et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Full-Length IL-33 Promotes Inflammation but not Th2 Response In Vivo in an ST2-Independent Fashion

(2012) I. G. Luzina et al.   JOURNAL OF IMMUNOLOGY

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human exhaled breath analysis

(2011) Todor A. Popov   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Serum IL-33 levels are raised in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis

(2011) Koichi Yanaba et al.   CLINICAL RHEUMATOLOGY

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

(2011) Jenny M Mjösberg et al.   NATURE IMMUNOLOGY

Standardized tape stripping prior to patch testing induces upregulation of Hsp90, Hsp70, IL-33, TNF-α and IL-8/CXCL8 mRNA: new insights into the involvement of ‘alarmins’

(2010) Heinrich Dickel et al.   CONTACT DERMATITIS

Mechanical injury polarizes skin dendritic cells to elicit a TH2 response by inducing cutaneous thymic stromal lymphopoietin expression

(2010) Michiko K. Oyoshi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The IL1-like cytokine IL33 and its receptor ST2 are abnormally expressed in the affected skin and visceral organs of patients with systemic sclerosis

(2009) M. Manetti et al.   ANNALS OF THE RHEUMATIC DISEASES

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

Antifibrotic action of pirfenidone and prednisolone: Different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis

(2008) Hisashi Oku et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY