Three Novel Loci for Infant Head Circumference Identified by a Joint Association Analysis

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

(2019) Simon Haworth et al.   Nature Communications

GARFIELD classifies disease-relevant genomic features through integration of functional annotations with association signals

(2019) Valentina Iotchkova et al.   NATURE GENETICS

Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity

(2019) Wei Chen et al.   Frontiers in Cellular Neuroscience

Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment

(2018) Igor Pomytkin et al.   CNS Neuroscience & Therapeutics

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

(2018) Jeanne E. Savage et al.   NATURE GENETICS

Multi-trait analysis of genome-wide association summary statistics using MTAG

(2018) Patrick Turley et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

(2018) Ting Qi et al.   Nature Communications

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

(2018) David M. Howard et al.   Nature Communications

Associations between birth characteristics and age-related cognitive impairment and dementia: A registry-based cohort study

(2018) Miriam A. Mosing et al.   PLOS MEDICINE

Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes

(2018) Sreemathi Logan et al.   Molecular Metabolism

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

(2018) Loic Yengo et al.   HUMAN MOLECULAR GENETICS

Intracranial Volume and Head Circumference in Children with Unoperated Syndromic Craniosynostosis

(2018) R.William.F. Breakey et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis

(2018) Karin M. E. Andersson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

(2018) Michael J. Gandal et al.   SCIENCE

Forebrain-specific ablation of phospholipase Cγ1 causes manic-like behavior

(2017) Y R Yang et al.   MOLECULAR PSYCHIATRY

Association analysis identifies 65 new breast cancer risk loci

(2017) Kyriaki Michailidou et al.   NATURE

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

The association between weight, height, and head circumference reconsidered

(2017) Christiane Scheffler et al.   PEDIATRIC RESEARCH

Reference curves of birth weight, length, and head circumference for gestational ages in Yogyakarta, Indonesia

(2016) Ekawaty L. Haksari et al.   BMC Pediatrics

Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer’s disease with OSBPL6, PTPRG and PDCL3

(2016) C Herold et al.   MOLECULAR PSYCHIATRY

Genome-wide associations for birth weight and correlations with adult disease

(2016) Momoko Horikoshi et al.   NATURE

Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

(2016) Aysu Okbay et al.   NATURE GENETICS

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Novel genetic loci underlying human intracranial volume identified through genome-wide association

(2016) Hieab H H Adams et al.   NATURE NEUROSCIENCE

The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation and neuroplasticity

(2016) Adam H. Dyer et al.   NEUROSCIENCE

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

PLCG1 mutations in cutaneous T-cell lymphomas

(2014) José P. Vaqué et al.   BLOOD

A novel common variant in DCST2 is associated with length in early life and height in adulthood

(2014) Ralf J.P. van der Valk et al.   HUMAN MOLECULAR GENETICS

Expression of STRBP mRNA in patients with cryptorchidism and Down’s syndrome

(2014) M. Salemi et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Maternal Urinary Iodine Concentration up to 1.0 mg/L Is Positively Associated with Birth Weight, Length, and Head Circumference of Male Offspring

(2014) Filip Rydbeck et al.   JOURNAL OF NUTRITION

Negative Regulation of Grb10 Interacting GYF Protein 2 on Insulin-Like Growth Factor-1 Receptor Signaling Pathway Caused Diabetic Mice Cognitive Impairment

(2014) Jing Xie et al.   PLoS One

New population-based references for birth weight, length, and head circumference in singletons and twins from 23 to 43 gestation weeks

(2013) Ulla Sankilampi et al.   ANNALS OF MEDICINE

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Effects of Growth Hormone–Releasing Hormone on Cognitive Function in Adults With Mild Cognitive Impairment and Healthy Older Adults

(2012) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

Neurodevelopmental effects of insulin-like growth factor signaling

(2012) John O’Kusky et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Common variants at 12q15 and 12q24 are associated with infant head circumference

(2012) H Rob Taal et al.   NATURE GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Evaluating the power to discriminate between highly correlated SNPs in genetic association studies

(2010) Miriam S. Udler et al.   GENETIC EPIDEMIOLOGY

Heritability of Head Size in Dutch and Australian Twin Families at Ages 0–50 Years

(2010) Dirk J. A. Smit et al.   Twin Research and Human Genetics

Mutations in STIL, Encoding a Pericentriolar and Centrosomal Protein, Cause Primary Microcephaly

(2009) Arun Kumar et al.   AMERICAN JOURNAL OF HUMAN GENETICS