A hybrid computational strategy to address WGS variant analysis in >5000 samples

Group-based variant calling leveraging next-generation supercomputing for large-scale whole-genome sequencing studies

(2015) Kristopher A. Standish et al.   BMC BIOINFORMATICS

An efficient and scalable analysis framework for variant extraction and refinement from population-scale DNA sequence data

(2015) Goo Jun et al.   GENOME RESEARCH

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

The UK10K project identifies rare variants in health and disease

(2015)   NATURE

Big Data: Astronomical or Genomical?

(2015) Zachary D. Stephens et al.   PLOS BIOLOGY

Inexpensive and Highly Reproducible Cloud-Based Variant Calling of 2,535 Human Genomes

(2015) Suyash S. Shringarpure et al.   PLoS One

Systematic comparison of variant calling pipelines using gold standard personal exome variants

(2015) Sohyun Hwang et al.   Scientific Reports

New mini- zincin structures provide a minimal scaffold for members of this metallopeptidase superfamily

(2014) Christine B Trame et al.   BMC BIOINFORMATICS

Mojo Hand, a TALEN design tool for genome editing applications

(2013) Kevin L Neff et al.   BMC BIOINFORMATICS

An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data

(2013) Y. Wang et al.   GENOME RESEARCH

Characterizing Bias in Population Genetic Inferences from Low-Coverage Sequencing Data

(2013) Eunjung Han et al.   MOLECULAR BIOLOGY AND EVOLUTION

Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium

(2013) Megan L. Grove et al.   PLoS One

An integrative variant analysis suite for whole exome next-generation sequencing data

(2012) Danny Challis et al.   BMC BIOINFORMATICS

An economic and energy-aware analysis of the viability of outsourcing cluster computing to a cloud

(2012) Carlos de Alfonso et al.   Future Generation Computer Systems-The International Journal of eScience

Low-coverage sequencing: Implications for design of complex trait association studies

(2011) Y. Li et al.   GENOME RESEARCH

Genotype and SNP calling from next-generation sequencing data

(2011) Rasmus Nielsen et al.   NATURE REVIEWS GENETICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

CloudBurst: highly sensitive read mapping with MapReduce

(2009) M. C. Schatz   BIOINFORMATICS

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

(2009) Bruce M. Psaty et al.   Circulation-Cardiovascular Genetics

Searching for SNPs with cloud computing

(2009) Ben Langmead et al.   GENOME BIOLOGY