Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells

Thymic regulatory T cells arise via two distinct developmental programs

(2019) David L. Owen et al.   NATURE IMMUNOLOGY

Generation of Foxp3+CD25− Regulatory T-Cell Precursors Requires c-Rel and IκBNS

(2019) Marc Schuster et al.   Frontiers in Immunology

Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus

(2018) Jennifer E. Cowan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

c-REL and IκBNSGovern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors

(2017) Marc Schuster et al.   JOURNAL OF IMMUNOLOGY

Control of Foxp3 stability through modulation of TET activity

(2016) Xiaojing Yue et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vitamin C Facilitates Demethylation of theFoxp3Enhancer in a Tet-Dependent Manner

(2016) Varun Sasidharan Nair et al.   JOURNAL OF IMMUNOLOGY

CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3 + T Cells

(2016) Jennifer E. Cowan et al.   Cell Reports

Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation

(2015) B-H Yang et al.   Mucosal Immunology

Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors

(2015) Nicolas Thiault et al.   NATURE IMMUNOLOGY

Down-regulation of Tet2 prevents TSDR demethylation in IL2 deficient regulatory T cells

(2014) Varun Sasidharan Nair et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Control of the Inheritance of Regulatory T Cell Identity by a cis Element in the Foxp3 Locus

(2014) Yongqiang Feng et al.   CELL

Differential Requirement for IL-2 and IL-15 during Bifurcated Development of Thymic Regulatory T Cells

(2014) Daniel Marshall et al.   JOURNAL OF IMMUNOLOGY

Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals

(2013) Xuguang Tai et al.   IMMUNITY

Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus

(2013) A. Toker et al.   JOURNAL OF IMMUNOLOGY

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

IκBNS Protein Mediates Regulatory T Cell Development via Induction of the Foxp3 Transcription Factor

(2012) Marc Schuster et al.   IMMUNITY

T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development

(2012) Naganari Ohkura et al.   IMMUNITY

Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

(2008) Matthew A. Burchill et al.   IMMUNITY

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY