Structural insights of homotypic interaction domains in the ligand-receptor signal transduction of tumor necrosis factor (TNF)

Crystal structure of the death effector domains of caspase-8

(2015) Chen Shen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids

(2013) Chris J. Vickers et al.   ACS Chemical Biology

Death domain complex of the TNFR-1, TRADD, and RIP1 proteins for death-inducing signaling

(2013) Young-Hoon Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Formation of the death domain complex between FADD and RIP1 proteins in vitro

(2012) Young-Hoon Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

IAPs limit activation of RIP kinases by TNF receptor 1 during development

(2012) Maryline Moulin et al.   EMBO JOURNAL

Cellular FLICE-like inhibitory proteins (c-FLIPs): Fine-tuners of life and death decisions

(2012) Selcen Öztürk et al.   EXPERIMENTAL CELL RESEARCH

A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

(2012) Laura S. Dickens et al.   MOLECULAR CELL

Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model

(2012) Kolja Schleich et al.   MOLECULAR CELL

Role of Bcl-2 family proteins and caspases in the regulation of apoptosis

(2011) Mohammad Shamsul Ola et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The death-fold superfamily of homotypic interaction motifs

(2011) Kristof Kersse et al.   TRENDS IN BIOCHEMICAL SCIENCES

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

(2011) N Vanlangenakker et al.   Cell Death & Disease

Three-dimensional Structure of the NLRP7 Pyrin Domain

(2010) Anderson S. Pinheiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL

(2010) Nicolai Fricker et al.   JOURNAL OF CELL BIOLOGY

Phosphorylation by polo-like kinase 1 induces the tumor-suppressing activity of FADD

(2010) M-S Jang et al.   ONCOGENE

The molecular regulation of programmed necrotic cell injury

(2010) David Moquin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

(2009) Simin Rahighi et al.   CELL

The Many Roles of FAS Receptor Signaling in the Immune System

(2009) Andreas Strasser et al.   IMMUNITY

Topology is the Principal Determinant in the Folding of a Complex All-alpha Greek Key Death Domain from Human FADD

(2009) Annette Steward et al.   JOURNAL OF MOLECULAR BIOLOGY

A New C-Terminal Cleavage Product of Procaspase-8, p30, Defines an Alternative Pathway of Procaspase-8 Activation

(2009) J. C. Hoffmann et al.   MOLECULAR AND CELLULAR BIOLOGY

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

(2009) Fiona L. Scott et al.   NATURE

Death receptor signal transducers: nodes of coordination in immune signaling networks

(2009) Nicholas S Wilson et al.   NATURE IMMUNOLOGY

Mechanism of procaspase-8 activation by c-FLIPL

(2009) J. W. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Monomer/Dimer Transition of the Caspase-Recruitment Domain of Human Nod1†,‡

(2008) Thiagarajan Srimathi et al.   BIOCHEMISTRY

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY