Article
Medicine, Research & Experimental
Chun Zhou, Yuanyuan Zhang, Jianghua Chen, Changlin Mei, Fei Xiong, Wei Shi, Wei Zhou, Xusheng Liu, Shiren Sun, Jianwei Tian, Ziliang Ye, Qimeng Wu, Xianhui Qin, Jianping Jiang, Fan Fan Hou
Summary: This study aimed to assess the correlation of serum advanced oxidation protein products (AOPP) levels with the risk of all-cause mortality in hemodialysis (HD) patients in China. The results showed that elevated serum AOPP levels were associated with a higher risk of all-cause mortality in Chinese maintenance HD patients, particularly in those with AOPP levels >=87 mu mol/L.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Review
Urology & Nephrology
Hongwei Wu, Qiang Li, Lijing Fan, Dewang Zeng, Xianggeng Chi, Baozhang Guan, Bo Hu, Yongping Lu, Chen Yun, Bernhard Kramer, Berthold Hocher, Fanna Liu, Lianghong Yin
Summary: A systematic review found that lower serum magnesium levels in hemodialysis patients are associated with higher all-cause mortality and cardiovascular mortality. Subgroup analysis suggests that a serum magnesium concentration <= 1.1 mmol/L may be a critical cutoff value to monitor in these patients.
Article
Hematology
Ling Yu, Yuan Zu, Jian Lu, Han Li, Shixiang Wang
Summary: This study retrospectively analyzed the mortality rates in 267 hemodialysis patients and found that average serum magnesium is a good indicator for predicting mortality in these patients, with higher levels of serum magnesium associated with better survival. Further research with larger sample sizes is needed to determine the optimal reference values for maximizing the benefits of magnesium.
BLOOD PURIFICATION
(2023)
Article
Transplantation
Erik Nilsson, Peter Stenvinkel, Sai Liu, Margaret R. Stedman, Glenn M. Chertow, Juergen Floege
Summary: Lower free testosterone and higher SHBG in serum are associated with higher risk of death or cardiovascular event in men undergoing chronic hemodialysis.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Review
Cardiac & Cardiovascular Systems
Huifang Wang, Jun Liu, Demin Xie, Hang Liu, Li Zhen, Dandan Guo, Xuemei Liu
Summary: The meta-analysis suggests that higher serum uric acid levels in maintenance hemodialysis patients are negatively correlated with cardiovascular mortality risk, and every 1 mg/dl increase in serum uric acid decreases the overall risks of all-cause and cardiovascular mortality.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Medicine, General & Internal
Katarzyna Aleksandra Lisowska, Hanna Storoniak, Monika Soroczynska-Cybula, Mateusz Maziewski, Alicja Debska-Slizien
Summary: The study found potential relationships between alpha-Klotho proteins and inflammatory markers in HD patients, but did not confirm their pathogenic link to cardiovascular mortality. Results showed the level of alpha-Klotho in HD patients was associated with age, but not with inflammatory markers.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Urology & Nephrology
Jianping Jiang, Yuanyuan Zhang, Jianghua Chen, Xiaobing Yang, Changlin Mei, Fei Xiong, Wei Shi, Wei Zhou, Xusheng Liu, Shiren Sun, Ping Zhang, Yixiang Zhang, Yanmin Zhang, Shuangxin Liu, Zhimin Zhang, Qizhan Lin, Yan Yu, Jianwei Tian, Weihong Luo, Xianhui Qin, Fan Fan Hou
Summary: The study found that in patients undergoing long-term hemodialysis, baseline skin autofluorescence (SAF) was significantly associated with the risk of all-cause and cardiovascular disease (CVD) mortality, but serum carboxymethyllysine (CML) was not significantly associated with mortality risk. Additionally, a stronger positive association between baseline SAF and all-cause mortality was found in participants with shorter dialysis vintage or lower C-reactive protein levels.
AMERICAN JOURNAL OF NEPHROLOGY
(2021)
Article
Urology & Nephrology
Teresa K. Chen, Jessica Fitzpatrick, Cheryl A. Winkler, Elizabeth A. Binns-Roemer, Celia P. Corona-Villalobos, Bernard G. Jaar, Stephen M. Sozio, Rulan S. Parekh, Michelle M. Estrella
Summary: In African American patients initiating hemodialysis, APOL1 high-risk status was associated with better subclinical cardiovascular disease measures but not mortality.
KIDNEY INTERNATIONAL REPORTS
(2021)
Review
Nutrition & Dietetics
Amir Bagheri, Sina Naghshi, Omid Sadeghi, Bagher Larijani, Ahmad Esmaillzadeh
Summary: The study found that higher dietary magnesium intake was associated with a reduced risk of all-cause and cancer mortality, but not CVD mortality. There were no significant associations between supplemental and total magnesium intakes with the risk of mortality. Linear dose-response analysis revealed that each additional intake of 100 mg/d of dietary magnesium was linked to a decreased risk of all-cause and cancer mortality.
ADVANCES IN NUTRITION
(2021)
Article
Nutrition & Dietetics
Ruoran Wang, Min He, Jianguo Xu
Summary: This study reveals an association between initial serum magnesium levels and mortality in TBI patients. Both abnormally low and high levels of serum magnesium are associated with a higher incidence of mortality in TBI patients.
Article
Endocrinology & Metabolism
Mingjia Yang, Junyan Miao, Lingbin Du, Jiayu Wang, Jing Yang, Jiayi Lu, Xikang Fan, Changzhi Huang, Zan Fu, Zekuan Xu, Mingyang Song, Hongxia Ma, Guangfu Jin, Zhibin Hu, Dong Hang, Hongbing Shen
Summary: The study found that there is an association between serum calcium concentrations and mortality in the general healthy population. Low and high calcium levels increase the risk of all-cause and cardiovascular disease mortality, while the risk of cancer mortality is linearly positively related to calcium concentrations.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Cardiac & Cardiovascular Systems
Xu Zhu, Iokfai Cheang, Yuan Tang, Mengsha Shi, Qingqing Zhu, Rongrong Gao, Shengen Liao, Wenming Yao, Yanli Zhou, Haifeng Zhang, Xinli Li
Summary: This study aimed to evaluate the relationships between serum carotenoid concentrations and mortality in hypertensive adults. The findings suggest that higher serum carotenoid concentrations are associated with lower risks of all-cause and cardiovascular mortality in hypertensive adults.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Urology & Nephrology
Min Li, Li-qiong Jiang, Meng-yu Zhang, Shu-su Liu, Rejean-Ruiel Regis Sawh, Jing Zheng, Yu Yan, Shi-mei Hou, Ke-qi Lu, Obadele Thorne, Bi-cheng Liu, Qing Qian, Yan-feng Wu, Min Yang, Bin Wang
Summary: This study explored the relationship and predictive value of serum fibroblast growth factor 21 (FGF21) with all-cause mortality, major adverse cardiovascular events (MACEs), and pneumonia in hemodialysis (HD) patients. The results showed that higher serum FGF21 levels were independent predictors of all-cause mortality, MACEs, and pneumonia in HD patients.
Article
Cardiac & Cardiovascular Systems
Ilse Evers, Esther Cruijsen, Iris Kornaat, Renate M. Winkels, Maria C. Busstra, Johanne M. Geleijnse
Summary: This study found that an adequate intake of magnesium may be important for lowering long-term mortality risk after myocardial infarction (MI), especially in patients treated with diuretics.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Nutrition & Dietetics
Lei Fan, Xiangzhu Zhu, Andrea Rosanoff, Rebecca B. Costello, Chang Yu, Reid Ness, Douglas L. Seidner, Harvey J. Murff, Christianne L. Roumie, Martha J. Shrubsole, Qi Dai
Summary: The study validated a model related to kidney reabsorption of magnesium, known as the magnesium depletion score (MDS), and found that MDS can be used to identify individuals with magnesium deficiency to reduce risks of systemic inflammation and cardiovascular disease mortality.
JOURNAL OF NUTRITION
(2021)