Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-Resistant Pseudomonas aeruginosa

Polymyxin B in Combination with Enrofloxacin Exerts Synergistic Killing against Extensively Drug-Resistant Pseudomonas aeruginosa

(2018) Yu-Wei Lin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Metabolic Analyses Revealed Time-Dependent Synergistic Killing by Colistin and Aztreonam Combination Against Multidrug-Resistant Acinetobacter baumannii

(2018) Mei-Ling Han et al.   Frontiers in Microbiology

Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii

(2017) Mohd Hafidz Mahamad Maifiah et al.   Scientific Reports

Colistin and Polymyxin B Dosage Regimens against Acinetobacter baumannii: Differences in Activity and the Emergence of Resistance

(2016) Soon-Ee Cheah et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Untargeted Metabolomics To Ascertain Antibiotic Modes of Action

(2016) Isabel M. Vincent et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are we there yet?

(2016) Thien B. Tran et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

An “Unlikely” Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI

(2016) Elena K. Schneider et al.   ACS Infectious Diseases

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

(2016) Mohd Hafidz Mahamad Maifiah et al.   Scientific Reports

Metabolomics as a Tool for Drug Discovery and Personalised Medicine. A Review

(2015) Annalaura Mastrangelo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii

(2015) Thien B Tran et al.   JOURNAL OF ANTIBIOTICS

The transcriptomic response ofAcinetobacter baumanniito colistin and doripenem alone and in combination in anin vitropharmacokinetics/pharmacodynamics model

(2015) Rebekah Henry et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Synergistic killing of NDM-producing MDRKlebsiella pneumoniaeby two ‘old’ antibiotics—polymyxin B and chloramphenicol

(2015) Nusaibah Abdul Rahim et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

New pharmacokinetic/pharmacodynamic studies of systemically administered colistin againstPseudomonas aeruginosaandAcinetobacter baumanniiin mouse thigh and lung infection models: smaller response in lung infection

(2015) Soon-Ee Cheah et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

(2015) Roger L Nation et al.   LANCET INFECTIOUS DISEASES

MetaboAnalyst 3.0—making metabolomics more meaningful

(2015) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

Functional metabolomics: from biomarker discovery to metabolome reprogramming

(2015) Bo Peng et al.   Protein & Cell

Impact of Antibiotics with Various Target Sites on the Metabolome of Staphylococcus aureus

(2014) Kirsten Dörries et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin and Polymyxin B: Peas in a Pod, or Chalk and Cheese?

(2014) R. L. Nation et al.   CLINICAL INFECTIOUS DISEASES

Direct infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control

(2014) Jennifer A Kirwan et al.   Scientific Data

Population Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients: Implications for Selection of Dosage Regimens

(2013) Ana M. Sandri et al.   CLINICAL INFECTIOUS DISEASES

10 x '20 Progress--Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America

(2013) H. W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Pharmacometabolomics: Implications for Clinical Pharmacology and Systems Pharmacology

(2013) R Kaddurah-Daouk et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

IDEOM: an Excel interface for analysis of LC–MS-based metabolomics data

(2012) Darren J. Creek et al.   BIOINFORMATICS

Antimicrobial resistance among Gram-negative bacilli isolated from Latin America: results from SENTRY Antimicrobial Surveillance Program (Latin America, 2008–2010)

(2012) Ana C. Gales et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

PeakML/mzMatch: A File Format, Java Library, R Library, and Tool-Chain for Mass Spectrometry Data Analysis

(2011) Richard A. Scheltema et al.   ANALYTICAL CHEMISTRY

PhoQ Mutations Promote Lipid A Modification and Polymyxin Resistance of Pseudomonas aeruginosa Found in Colistin-Treated Cystic Fibrosis Patients

(2011) Amanda K. Miller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin: new lessons on an old antibiotic

(2011) D. Yahav et al.   CLINICAL MICROBIOLOGY AND INFECTION

Contemporary activity of colistin and polymyxin B against a worldwide collection of Gram-negative pathogens: results from the SENTRY Antimicrobial Surveillance Program (2006-09)

(2011) A. C. Gales et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pharmacokinetic/Pharmacodynamic Investigation of Colistin against Pseudomonas aeruginosa Using an In Vitro Model

(2010) P. J. Bergen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance to Colistin in Acinetobacter baumannii Associated with Mutations in the PmrAB Two-Component System

(2009) M. D. Adams et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin in the 21st century

(2009) Roger L Nation et al.   CURRENT OPINION IN INFECTIOUS DISEASES

iPath: interactive exploration of biochemical pathways and networks

(2008) Ivica Letunic et al.   TRENDS IN BIOCHEMICAL SCIENCES