Photoimmunotherapy targeting biliary‐pancreatic cancer with humanized anti‐TROP2 antibody

Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma

(2019) Shinichiro Watanabe et al.   CANCER BIOLOGY & THERAPY

Cancer neovasculature-targeted near-infrared photoimmunotherapy (NIR-PIT) for gastric cancer: different mechanisms of phototoxicity compared to cell membrane-targeted NIR-PIT

(2019) Takashi Nishimura et al.   Gastric Cancer

Trends in pancreatic adenocarcinoma incidence and mortality in the United States in the last four decades; a SEER-based study

(2018) Anas M. Saad et al.   BMC CANCER

Endoscopic balloon dilation for benign gastric outlet obstruction: Does etiology matter?

(2018) Andrew McNeice et al.   GASTROINTESTINAL ENDOSCOPY

Photoinduced Ligand Release from a Silicon Phthalocyanine Dye Conjugated with Monoclonal Antibodies: A Mechanism of Cancer Cell Cytotoxicity after Near-Infrared Photoimmunotherapy

(2018) Kazuhide Sato et al.   ACS Central Science

Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer

(2017) Aditya Bardia et al.   JOURNAL OF CLINICAL ONCOLOGY

Therapy of Advanced Non–Small-Cell Lung Cancer With an SN-38-Anti-Trop-2 Drug Conjugate, Sacituzumab Govitecan

(2017) Rebecca Suk Heist et al.   JOURNAL OF CLINICAL ONCOLOGY

Combination photoimmunotherapy with monoclonal antibodies recognizing different epitopes of human epidermal growth factor receptor 2: an assessment of phototherapeutic effect based on fluorescence molecular imaging

(2016) Kimihiro Ito et al.   Oncotarget

Near infrared photoimmunotherapy with avelumab, an anti-programmed death-ligand 1 (PD-L1) antibody

(2016) Tadanobu Nagaya et al.   Oncotarget

Initial human experience of endoscopic ultrasound-guided photodynamic therapy with a novel photosensitizer and a flexible laser-light catheter

(2015) Jun-Ho Choi et al.   ENDOSCOPY

Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)*

(2015) David M. Goldenberg et al.   Oncotarget

Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer

(2015) Ali A. Maawy et al.   PLoS One

The effects of conjugate and light dose on photo-immunotherapy induced cytotoxicity

(2014) Takahito Nakajima et al.   BMC CANCER

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Photoimmunotherapy: Comparative effectiveness of two monoclonal antibodies targeting the epidermal growth factor receptor

(2014) Kazuhide Sato et al.   Molecular Oncology

Trop-2 Is a Determinant of Breast Cancer Survival

(2014) Federico Ambrogi et al.   PLoS One

Improving the Efficacy of Photoimmunotherapy (PIT) using a Cocktail of Antibody Conjugates in a Multiple Antigen Tumor Model

(2013) Takahito Nakajima et al.   Theranostics

Near-infrared Theranostic Photoimmunotherapy (PIT): Repeated Exposure of Light Enhances the Effect of Immunoconjugate

(2012) Makoto Mitsunaga et al.   BIOCONJUGATE CHEMISTRY

Significantly upregulated TACSTD2 and Cyclin D1 correlate with poor prognosis of invasive ductal breast cancer

(2012) Hong Lin et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

TROP2 Correlates with Microvessel Density and Poor Prognosis in Hilar Cholangiocarcinoma

(2012) Shanglei Ning et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Humanized Anti-Trop-2 IgG-SN-38 Conjugate for Effective Treatment of Diverse Epithelial Cancers: Preclinical Studies in Human Cancer Xenograft Models and Monkeys

(2011) T. M. Cardillo et al.   CLINICAL CANCER RESEARCH

Expression of Trop2 Cell Surface Glycoprotein in Normal and Tumor Tissues

(2011) Lara P. Stepan et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

(2011) Makoto Mitsunaga et al.   NATURE MEDICINE

Systematic review: photodynamic therapy for unresectable cholangiocarcinoma

(2009) Fei Gao et al.   Journal of Hepato-Biliary-Pancreatic Sciences

High expression of TROP2 correlates with poor prognosis in pancreatic cancer

(2008) D Fong et al.   BRITISH JOURNAL OF CANCER

Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers

(2008) J. Wang et al.   MOLECULAR CANCER THERAPEUTICS