FoxO1 Overexpression Ameliorates TNF-α-Induced Oxidative Damage and Promotes Osteogenesis of Human Periodontal Ligament Stem Cells via Antioxidant Defense Activation

FOXO1 Overexpression Attenuates Tubulointerstitial Fibrosis and Apoptosis in Diabetic Kidneys by Ameliorating Oxidative Injury via TXNIP-TRX

(2019) Linlin Ji et al.   Oxidative Medicine and Cellular Longevity

Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium

(2019) Atsushi Tomokiyo et al.   STEM CELLS AND DEVELOPMENT

Vitamin D3 contributes to enhanced osteogenic differentiation of MSCs under oxidative stress condition via activating the endogenous antioxidant system

(2018) J. Zhou et al.   OSTEOPOROSIS INTERNATIONAL

Ochratoxin A-Induced Apoptosis of IPEC-J2 Cells through ROS-Mediated Mitochondrial Permeability Transition Pore Opening Pathway

(2017) Hong Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Role of FOXO transcription factors in crosstalk between mitochondria and the nucleus

(2017) Sujin Kim et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Increased levels of the T-helper 22-associated cytokine (interleukin-22) and transcription factor (aryl hydrocarbon receptor) in patients with periodontitis are associated with osteoclast resorptive activity and severity of the disease

(2017) J. Díaz-Zúñiga et al.   JOURNAL OF PERIODONTAL RESEARCH

Stem cell-based tooth and periodontal regeneration

(2017) L Hu et al.   ORAL DISEASES

Functional block of IL-17 cytokine promotes bone healing by augmenting FOXO1 and ATF4 activity in cortical bone defect model

(2017) M. Dixit et al.   OSTEOPOROSIS INTERNATIONAL

Periodontitis: facts, fallacies and the future

(2017) Jørgen Slots   PERIODONTOLOGY 2000

Human Umbilical Cord MSCs as New Cell Sources for Promoting Periodontal Regeneration in Inflammatory Periodontal Defect

(2017) Fengqing Shang et al.   Theranostics

Evaluation of Salivary and Serum Antioxidant and Oxidative Stress Statuses in Patients with Chronic Periodontitis: A Case-Control Study

(2017) Fatemeh Ahmadi-Motamayel et al.   Frontiers in Physiology

Pathways that Regulate ROS Scavenging Enzymes, and Their Role in Defense Against Tissue Destruction in Periodontitis

(2017) Hiroyuki Kanzaki et al.   Frontiers in Physiology

Drp1-dependent mitochondrial fission mediates osteogenic dysfunction in inflammation through elevated production of reactive oxygen species

(2017) Ling Zhang et al.   PLoS One

Resveratrol prevents alveolar bone loss in an experimental rat model of periodontitis

(2016) Govinda Bhattarai et al.   Acta Biomaterialia

Effects of overexpressing FoxO1 on apoptosis in glomeruli of diabetic mice and in podocytes cultured in high glucose medium

(2016) Wen Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Porphyromonas gingivalis-induced production of reactive oxygen species, tumor necrosis factor-α, interleukin-6, CXCL8 and CCL2 by neutrophils from localized aggressive periodontitis and healthy donors: modulating actions of red blood cells and resolvin E1

(2016) C. Damgaard et al.   JOURNAL OF PERIODONTAL RESEARCH

Tumor Necrosis Factor-α Attenuates the Osteogenic Differentiation Capacity of Periodontal Ligament Stem Cells by Activating PERK Signaling

(2016) Jun Tan et al.   JOURNAL OF PERIODONTOLOGY

TNF-α Inhibits FoxO1 by Upregulating miR-705 to Aggravate Oxidative Damage in Bone Marrow-Derived Mesenchymal Stem Cells during Osteoporosis

(2016) Li Liao et al.   STEM CELLS

TNF and ROS Crosstalk in Inflammation

(2016) Heiko Blaser et al.   TRENDS IN CELL BIOLOGY

Long noncoding RNA related to periodontitis interacts with miR-182 to upregulate osteogenic differentiation in periodontal mesenchymal stem cells of periodontitis patients

(2016) L Wang et al.   Cell Death & Disease

FOXO1 Deletion Reduces Dendritic Cell Function and Enhances Susceptibility to Periodontitis

(2015) Wenmei Xiao et al.   AMERICAN JOURNAL OF PATHOLOGY

Periodontitis promotes the proliferation and suppresses the differentiation potential of human periodontal ligament stem cells

(2015) WEI ZHENG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Effects of TNF-α on Cementoblast Differentiation, Mineralization, and Apoptosis

(2015) Y.L. Wang et al.   JOURNAL OF DENTAL RESEARCH

Foxo1 Is a T Cell–Intrinsic Inhibitor of the RORγt-Th17 Program

(2015) Alexandra Lainé et al.   JOURNAL OF IMMUNOLOGY

Activation of FoxO1/ PGC-1α prevents mitochondrial dysfunction and ameliorates mesangial cell injury in diabetic rats

(2015) Lina Wu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Redox regulation of FoxO transcription factors

(2015) Lars-Oliver Klotz et al.   Redox Biology

Antioxidative fullerol promotes osteogenesis of human adipose-derived stem cells

(2014) Xinlin Yang et al.   International Journal of Nanomedicine

A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response

(2014) Dan Shao et al.   Nature Communications

TNF-α-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-XL

(2010) J J Kim et al.   CELL DEATH AND DIFFERENTIATION

FoxO1 Is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts

(2010) Marie-Therese Rached et al.   Cell Metabolism

FoxO1: A molecule for all seasons

(2010) Stavroula Kousteni   JOURNAL OF BONE AND MINERAL RESEARCH

Mechanisms and control of pathologic bone loss in periodontitis

(2010) P. Mark Bartold et al.   PERIODONTOLOGY 2000

Lipid peroxidation in relation to ageing and the role of endogenous aldehydes in diabetes and other age-related diseases

(2009) L.F. Dmitriev et al.   AGEING RESEARCH REVIEWS

Induction of indoleamine 2, 3-dioxygenase by death receptor activation contributes to apoptosis of melanoma cells via mitochondrial damage-dependent ROS accumulation

(2009) Turgut Cetindere et al.   CELLULAR SIGNALLING

Lipid peroxidation and antioxidant activity in saliva of periodontitis patients: effect of smoking and periodontal treatment

(2008) Arndt Guentsch et al.   Clinical Oral Investigations

TNF-induced mitochondrial damage: a link between mitochondrial complex I activity and left ventricular dysfunction

(2008) Nithya Mariappan et al.   FREE RADICAL BIOLOGY AND MEDICINE