Review
Clinical Neurology
Huan-Yu Xiong, Zhi-Jie Zhang, Xue-Qiang Wang
Summary: The study provides a comprehensive review on the global scientific research status of comorbid pain and inflammation from 1981 to 2019, revealing a significant increase in research output in neurosciences, pharmacology/pharmacy, and clinical neurology fields. The USA, China, and England are the top countries in terms of research output.
PAIN RESEARCH & MANAGEMENT
(2021)
Article
Neurosciences
Chong Li, Xiaoyi Shu, Xiangyun Liu
Summary: This study provides a bibliometric analysis of global research trends in pain after stroke over the past 12 years. The analysis reveals a continuous but unstable growth in the number of publications in this field. The research focus is on shoulder pain after stroke and central post-stroke pain.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Article
Psychiatry
Yuanyuan Chen, Peijun Ju, Qingrong Xia, Peng Cheng, Jianliang Gao, Loufeng Zhang, Hua Gao, Xialong Cheng, Tao Yu, Junwei Yan, Qiru Wang, Cuizhen Zhu, Xulai Zhang
Summary: This study aimed to investigate the association between pain catastrophizing and comorbidity of major depressive disorder (MDD) and chronic pain (CP). The results showed that pain catastrophizing and anxiety were more severe in the comorbidity group compared to the MDD-only group and healthy control group. Pain catastrophizing and anxiety may potentially impact the comorbidity of depression and chronic pain.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Oncology
Chunyu Li, Can Zhao, Jingjing Zhao, Min Wang, Furong Luo, Jianwei Zhou
Summary: This study conducted a bibliometric analysis on acupuncture therapy for cancer pain, including the number of publications, international collaborations, keywords, and citations. The results showed an increasing trend in the number of publications, with China and the United States being the main contributors. The hot topics in this field are acupuncture, pain management, and quality of life. Future studies may focus on breast cancer pain, aromatase inhibitor-induced arthralgia, and chemotherapy-induced peripheral neuropathy.
FRONTIERS IN ONCOLOGY
(2023)
Article
Immunology
Hsien-Yin Liao, Senthil Kumaran Satyanarayanan, Yi-Wen Lin, Kuan-Pin Su
Summary: This study investigated the specific efficacy and immune effects of acupuncture on pain and depression in patients with comorbid chronic pain and major depressive disorder (MDD). The results showed that specific acupoints for pain did not show greater efficacy than depression-specific acupoints, and pain-specific acupoints even improved depression symptoms better. The study suggests that pain and depression may share common biological mechanisms.
BRAIN BEHAVIOR AND IMMUNITY
(2023)
Article
Nutrition & Dietetics
Birgit Mazurek, Matthias Rose, Holger Schulze, Christian Dobel
Summary: This article proposes a more differentiated approach in the field of systems medicine for the treatment of chronic diseases and patients. It highlights the importance of considering specific and individualized therapeutic strategies due to the potential differences in symptoms and comorbidities that may result from various pathological factors. Using the example of tinnitus, depression, and chronic pain, the article emphasizes the significance of understanding the interplay between symptoms and biomarkers in order to gain a deeper mechanistic understanding of diseases and develop personalized treatment strategies.
Review
Neurosciences
Siqi Yang, Bingyuan Zhang, Di Wang, Suwan Hu, Wenli Wang, Cunming Liu, Zifeng Wu, Chun Yang
Summary: Patients with chronic pain often experience depressive symptoms, and the interaction between these two conditions can worsen over time, resulting in increased intensity and duration of symptoms. The comorbidity of pain and depression presents a significant challenge to healthcare and quality of life, as it is difficult to diagnose and treat effectively. It is therefore important to explore the molecular mechanisms underlying this comorbidity in order to identify new therapeutic targets.
BRAIN RESEARCH BULLETIN
(2023)
Article
Psychology, Multidisciplinary
Ling Chen, Tingting Ren, Yun Tan, Hong Li
Summary: This study analyzed the research hotspots and frontiers in breast cancer survivors with depression through visualization of literature. It found that the United States and China were the most productive countries, with the University of California, Los Angeles and the University of Toronto being the most productive institutions. Five research hotspots related to depression in breast cancer were identified, including post-traumatic growth, spiritual interventions, cognitive-behavioral therapy, physical activity, and symptom cluster management.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Teng He, Zifeng Wu, Xinying Zhang, Hanyu Liu, Yuanyuan Wang, Riyue Jiang, Cunming Liu, Kenji Hashimoto, Chun Yang
Summary: This study used bibliometric analysis to investigate the role of BDNF in depression. It provides a comprehensive summary and analysis of this research topic, offering valuable information for beginners.
Review
Psychology, Multidisciplinary
Runfang Wang, Yaokun Shan
Summary: This study utilized bibliometric methods to analyze the hotspots and frontiers in postpartum depression research from 2017 to 2021. The results showed that the research hotspots in the field of postpartum depression in the past five years mainly focused on the risk factors for PPD and the impact of the COVID-19 epidemic on PPD. Furthermore, providing various aspects of social and family support to women with PPD is also a research trend. The study provides valuable information for guiding future research topics and development directions.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Immunology
Yujie Fu, Chan Gong, Chenchen Zhu, Weiquan Zhong, Jiabao Guo, Binglin Chen
Summary: In this study, a bibliometric analysis was conducted to analyze neuropathic pain in neurodegenerative diseases. The findings showed that the United States had the highest number of publications, citations, and H-indexes in the field of neuropathic pain. Multiple sclerosis, Parkinson's disease, and Alzheimer's disease were the most studied neurodegenerative diseases. The study also identified microglia-regulated neuroinflammation as a hot research topic and deep brain stimulation and gamma knife radiosurgery as popular treatment methods.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Medicine, General & Internal
Yu Kondo, Yuzo Ashida, Yuki Nomura, Takahiro Miki, Yuta Watanabe, Tsuneo Takebayashi
Summary: The purpose of this study was to analyze the top 100 cited articles in nonspecific neck pain (NSNP) research. The articles were selected based on their citation counts from the Web of Science database. The analysis focused on factors such as total citation count, journal, study design, and country of origin. The findings revealed the most influential articles and provided insights into the historical advances in NSNP research.
Article
Psychiatry
Xiang-jie Guo, Peng Wu, Xiao Jia, Yi-ming Dong, Chun-mei Zhao, Nian-nian Chen, Zhi-yong Zhang, Yu-ting Miao, Ke-ming Yun, Cai-rong Gao, Yan Ren
Summary: This study analyzed the literature on depression biomarkers using bibliometric methods and visualization tools, revealing research hotspots and frontiers. The findings of this study provide important guidance for future research in the field of depression biomarkers.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Behavioral Sciences
Sakina J. Rizvi, Wiebke Gandhi, Tim Salomons
Summary: Pain disorders and Major Depressive Disorder (MDD) often coexist in clinical settings, potentially due to deficits in reward processing. Environmental events in conjunction with reward impairment diathesis may worsen symptoms, creating a negative feedback loop.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Review
Clinical Neurology
Cheng-Cheng Wu, Yi-Zu Wang, Hao-Yu Hu, Xue-Qiang Wang
Summary: This study analyzed scientific research on the comorbidity of cancer and pain globally from 2010 to 2019, revealing a significant increase in the number of related papers. The research topics mainly focused on oncology, clinical neurology, and healthcare science services, with breast cancer being the predominant topic in the papers related to the comorbidity of cancer and pain.
JOURNAL OF PAIN RESEARCH
(2021)
Article
Oncology
Meng-Si Peng, Chang-Cheng Chen, Juan Wang, Yi-Li Zheng, Jia-Bao Guo, Ge Song, Xue-Qiang Wang
Summary: Up to 90% of the human genome is transcribed into Long-noncoding RNAs (lncRNAs), which play a crucial role in various biological processes and are linked to the development of complex human diseases. A bibliometric analysis was conducted to identify the most influential papers in lncRNAs research and to understand the factors contributing to their success in citation.
CANCER BIOLOGY & THERAPY
(2021)
Article
Biotechnology & Applied Microbiology
Juan Zhang, Rui Wang, Yili Zheng, Jiao Xu, Ya Wu, Xueqiang Wang
Summary: WBV training can improve the activation rate of knee muscles in patients with KOA, with the most effective combination being a vibration frequency of 20 Hz and a knee flexion angle of 60 degrees. Individual differences and rehabilitation purposes should be considered when selecting vibration parameters and knee angle to effectively increase neuromuscular activity in patients with KOA.
BIOMED RESEARCH INTERNATIONAL
(2021)
Article
Clinical Neurology
Yi-Li Zheng, Hao-Yu Hu, Xiao-Chen Liu, Xuan Su, Pei-Jie Chen, Xue-Qiang Wang
Summary: The study found that whole-body vibration (WBV) exercise can effectively alleviate the anticipatory delay of core muscles in nonspecific low back pain (NSLBP) patients, but further research is needed to determine the long-term effects.
PAIN RESEARCH & MANAGEMENT
(2021)
Article
Neurosciences
Jia-Bao Guo, Bing-Lin Chen, Ge Song, Yi-Li Zheng, Yi Zhu, Zheng Yang, Xuan Su, Ying Wang, Qing Cao, Pei-Jie Chen, Xue-Qiang Wang
Summary: Exercise therapy may have a positive impact on peripheral neuropathic pain by affecting miRNA and mRNA in the dorsal root ganglion, with certain genes potentially playing a role in NP through enriched pathways. The study sheds light on adaptive mechanisms post-exercise for NP and highlights the potential involvement of specific DEGs in NP pathogenesis.
Review
Behavioral Sciences
Yi-Li Zheng, Jia-Bao Guo, Ge Song, Zheng Yang, Xuan Su, Pei-Jie Chen, Xue-Qiang Wang
Summary: This review discusses the characteristics and functions of circRNAs in neuropathic pain. Through the review of emerging evidence, it is found that deregulation of circRNAs is involved in the development of neuropathic pain and they can modulate downstream gene expression by sponging miRNAs. These findings provide a theoretical basis for the use of circRNAs as biomarkers and therapeutic targets in neuropathic pain.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Biochemistry & Molecular Biology
Yi-Li Zheng, Xuan Su, Yu-Meng Chen, Jia-Bao Guo, Ge Song, Zheng Yang, Pei-Jie Chen, Xue-Qiang Wang
Summary: This study investigates the microRNA-related molecular mechanisms of neuropathic pain (NP) and their transcriptional regulation in NP. Several dysregulated miRNAs and their target genes associated with NP were identified, and it was suggested that targeting genes on transient receptor potential channels, voltage-gated sodium channels, and voltage-gated calcium channels could be utilized for pain relief. Further understanding of signal processing and modulation in neuronal ensembles is crucial for future therapeutic success.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Neurosciences
Ge Song, Wei-Ming Zhang, Yi-Zu Wang, Jia-Bao Guo, Yi-Li Zheng, Zheng Yang, Xuan Su, Yu-Meng Chen, Qing Xie, Xue-Qiang Wang
Summary: Exercise can help inhibit neuropathic pain, and this study used swimming exercise on CCI rats to explore the mechanism. RNA sequencing was employed to investigate the transcriptomes of spinal dorsal horns, and the biological functions of lncRNAs and mRNAs were analyzed.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Article
Neurosciences
Shu-Hao Du, Yi-Li Zheng, Yong-Hui Zhang, Ming-Wen Wang, Xue-Qiang Wang
Summary: This study offers a visual method for observing the global research trends in DPNP from 2011 to 2021. The research in the field mainly focuses on Endocrinology Metabolism, Clinical neurology and Neurosciences, with the United States leading in terms of publications, citations, and research contribution.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Review
Geriatrics & Gerontology
Jing Luo, Hui-Qi Zhu, Bo Gou, Yi-Li Zheng
Summary: Diabetic neuropathic pain (DNP) is a common disease with high incidence worldwide. Drug therapy, although commonly used, has various side effects, leading to increased interest in exercise therapy. Understanding the mechanisms of exercise therapy for DNP is important in selecting appropriate treatment methods due to the unclear pathological mechanism of DNP.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Geriatrics & Gerontology
Ji-Wei Chen, Yue Guan, Yi-Li Zheng, Kun Zhu
Summary: Research on exercise-based non-pharmacological treatments for movement disorders has been on the rise from 2010 to 2021. The United States maintains a dominant position in this area, with the League of European Research Universities and Movement Disorders journals publishing the highest number of academic articles. In the last five years, research focus has been on treatments, research advances, and clinical treatments.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Review
Immunology
Lin Zhang, Yi-Li Zheng, Rui Wang, Xue-Qiang Wang, Hao Zhang
Summary: Osteoporosis is a common disease among the elderly, particularly postmenopausal women, which weakens bones and disrupts the balance between bone formation and resorption. Moderate exercise serves as an effective non-drug treatment by increasing bone formation and relieving osteoporosis. Exercise affects apoptosis and autophagy through myohormone release and the secretion of anti-inflammatory cytokines. Additionally, exercise can impact the epigenetic processes involved in bone metabolism.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Neurosciences
Hui Liu, Yi-Li Zheng, Xue-Qiang Wang
Summary: Finding new biomarkers and molecular targets for the treatment of osteoarthritis is a significant challenge. RNA methylation, particularly N-6-methyladenosine (m(6)A), plays a crucial role in the occurrence and progression of osteoarthritis by affecting various signaling pathways. Targeting m(6)A modification may provide a promising therapeutic strategy for osteoarthritis.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Article
Computer Science, Information Systems
Xianchang Meng, Yili Zheng, Weiping Liu
Summary: This paper designs a non-destructive detection device for plant leaf expansion pressure in order to promote research on plant leaf expansion pressure and achieve precision irrigation. The design is based on leaf expansion pressure probe technology, which effectively monitors plant leaf expansion pressure by detecting the feedback of the leaf under constant pressure. The stability and calibration model of the sensor were tested, and the experiments showed satisfactory results. The importance of this device is rated 8 out of 10.
Article
Food Science & Technology
Xueyan Zhu, Deyu Shen, Ruipeng Wang, Yili Zheng, Shuchai Su, Fengjun Chen
Summary: A maturity grading and identification model for Camellia oleifera fruit has been developed using an unsupervised image clustering model. The model accurately grades and identifies the maturity of the fruit.
Article
Chemistry, Multidisciplinary
Peng Guan, Lichen Zhu, Yili Zheng
Summary: This study used an optical camera to obtain forest images and calculated the absolute greenness index (GEI) data to fit the seasonal variation curve of forest phenology. The GRU neural network model was introduced to train and analyze the GEI data, and its performance was evaluated using MSE, RMSE, and MAE methods. The model was then used to predict the trend of GEI data for the next 60 days.
APPLIED SCIENCES-BASEL
(2023)
