Article
Nanoscience & Nanotechnology
Reza Karimi, Sajad Rezazadeh, Mohammad Raad
Summary: This paper presents a three-dimensional study of the nitrogen and oxygen mixing process in a T-type micromixer, and validates the improvement of mixing quality by introducing SAR structures. It is found that at low Reynolds numbers, the mixing quality is high, and increasing the cross-section area of mixing units can enhance mixing quality.
MICROFLUIDICS AND NANOFLUIDICS
(2021)
Article
Nanoscience & Nanotechnology
A. Bahari, A. Mirzaei, M. Taghipoor
Summary: In this paper, the conventional 2D H-filter is modified to 3D multi-layer structures fabricated by low-cost xurography. The extraction efficiency of different 3D structures is studied and compared with the conventional 2D H-filter. Numerical simulations show a good agreement with experimental observations, demonstrating that the 3D H-filters have higher extraction efficiency at the same Reynolds number. The higher efficiency at smaller sizes makes these structures beneficial for low-cost and commercial applications.
MICROFLUIDICS AND NANOFLUIDICS
(2022)
Article
Engineering, Electrical & Electronic
Guojun Liu, Meng Wang, Luntao Dong, Duanyi Zhu, Conghui Wang, Yanhui Jia, Xinbo Li, Jibo Wang
Summary: A novel Y-shaped split-and-recombine (SAR) micromixer is proposed, which demonstrates better mixing performance and smaller pressure loss due to its three-dimensional structure, splitting recombination, and chaotic convection mechanism. Simulation and experimental results show that the channel aspect ratio has a significant impact on the mixing performance and pressure loss of the micromixer. The micromixer has broad application prospects in chemical synthesis, biochemical analysis, and biomedicine.
SENSORS AND ACTUATORS A-PHYSICAL
(2022)
Article
Chemistry, Analytical
Ranjitsinha R. Gidde
Summary: This paper analyzed the mixing performance of three types of baffle-based passive micromixers using numerical simulation, finding different mixing mechanisms at different Reynolds numbers and their suitability for chemical, biochemical, and medical applications.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Engineering, Multidisciplinary
S. M. H. Mirkarimi, M. J. Hosseini, Y. Pahamli
Summary: In this study, four curved passive micromixers with different arrangements of cylindrical obstacles alongside with simple curved channel were considered and assessed. The results showed that the special arrangement of the obstacles led to an increase in mixing efficiency at low Reynolds numbers, with Case-B and Case-E performing the best among different configurations.
ALEXANDRIA ENGINEERING JOURNAL
(2023)
Article
Engineering, Mechanical
Mojtaba Zeraatkar, Marco Donato de Tullio, Alessio Pricci, Francesco Pignatelli, Gianluca Percoco
Summary: This study introduces an alternative construction for microfluidic micromixers using the effect of extruded filaments in FDM technique. Experimental and numerical studies showed that the geometrical features on microchannels can act as ridges and enhance chaotic mixing through transverse movement of fluids. Compared to other methods, FDM offers a simpler fabrication process with inherent properties that enhance mixing processes.
RAPID PROTOTYPING JOURNAL
(2021)
Article
Mechanics
Ekta Tripathi, Promod Kumar Patowari, Sukumar Pati
Summary: In this study, the influence of the shapes of passive micromixers on the mixing efficiency of fluids in microfluidic devices such as Lab on a chip and mu-total analysis systems was investigated. The mixing efficiency of straight, serpentine, and spiral micromixers was compared, while keeping the same axial length of each channel to compact the size of the microfluidic device. Numerical simulations were performed for a range of Reynolds numbers in each micromixer. The results showed that the spiral micromixer had the highest mixing efficiency among all the considered micromixers.
Article
Materials Science, Multidisciplinary
Jacob T. Brooks, Jeremy Cribb, Michael R. Falvo, Richard Superfine
Summary: Magnetically actuating surface-attached post (ASAP) arrays have great potential in microfluidic flow control, and a fabrication protocol has been developed using photolithography processes to create high aspect ratio ASAP with small cross-sectional areas.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Engineering, Chemical
Lili Zou, Yao Gong, Longsheng Chen, Xiang Yi, Wankun Liu
Summary: A novel two-dimensional passive micromixer was designed, fabricated, and characterized based on the concept of unbalanced convergence-divergence-splits and reverse-collisions-recombination of fluid streams, showing improved mixing performance. By introducing multiple-vortex and reverse-collisions-recombination, the micromixer achieved almost complete mixing and enhanced fabrication accuracy reliability, providing insights for microfluidic applications with complex structures.
CHEMICAL ENGINEERING SCIENCE
(2021)
Article
Engineering, Chemical
Fahizan Mahmud, Khairul Fikri Tamrin, Shahrol Mohamaddan, Nobuo Watanabe
Summary: This study simplifies the manufacturing process and improves mixing performance by externally applying ultrasound and thermal energy upstream of the micromixer. The Dean micromixer shows higher mixing performance compared to T- and Y-micromixers, with about 27% improvement for Reynolds numbers between 40 and 100.
Article
Mechanics
Yanxing Wang, Hui Wan, Tie Wei, John Abraham
Summary: The heat and mass transfer characteristics of a simple shear flow over a surface covered with staggered herringbone structures were numerically investigated using the lattice Boltzmann method. Two flow motions, spiral flow oscillation and flow recirculation, were identified. These flow motions couple together to form a complex transport mechanism. The results show that the total transfer rate follows a power law relationship with the Schmidt number and Reynolds number.
Article
Energy & Fuels
M. S. C. A. Brito, R. J. Santos, M. M. Dias, J. C. B. Lopes, C. P. Fonte
Summary: The study proposes a model to estimate the distribution of mixing length scales in SR mixers, which is compared to Computational Fluid Dynamics simulations. Results show that the mixing efficiency depends on the decay rate of non-ideal striation thickness, and an SR mixer must be 1.81 times longer than an ideal one to achieve complete mixedness.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2022)
Article
Physics, Condensed Matter
J. Manuel Hernandez Meza, J. Rodrigo Velez-Cordero, A. Ramirez Saito, S. Aranda-Espinoza, Jose L. Arauz-Lara, Bernardo Yanez Soto
Summary: In this study, we experimentally investigated the motion of 1 & mu;m single particles interacting with functionalized walls under low and moderate ionic strengths conditions. We found that there is a retardation effect on diffusion when the particles interact with negatively charged walls, especially in the perpendicular component. The decrease in diffusion is related to the particle-wall distance.
JOURNAL OF PHYSICS-CONDENSED MATTER
(2022)
Article
Engineering, Chemical
Yaran Yin, Weiyang Chen, Conghao Wu, Xianming Zhang, Taotao Fu, Chunying Zhu, Youguang Ma
Summary: In this study, a split-and-recombine (SAR) microreactor composed of convergent-divergent arc channel and rectangular obstacles was designed and its enhancement characteristics in a gas-liquid rapid chemical absorption system were explored. The study found that the SAR structure caused bubble velocity pulsation and revealed the squeezing mechanism for bubble breakup. Different breakup patterns had an influence on the mass transfer performance.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Energy & Fuels
Tamara Al-Hassan, Charbel Habchi, Thierry Lemenand, Fouad Azizi
Summary: The study investigates a new type of SAR mixer characterized by double separation and recombination, aiming to increase mixture homogeneity in a shorter distance. The results compared against two commonly used SAR mixers in the literature show that the proposed mixer demonstrates superior performance with better mixing quality and lower energy consumption.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2021)
Article
Environmental Sciences
Mostafa Rostamian, Hadi Hosseini, Vafa Fakhri, Pardis Yousefi Talouki, Masoud Farahani, Ali Jalali Gharehtzpeh, Vahabodin Goodarzi, Chia-Hung Su
Summary: This study proposed eco-friendly adsorbents based on poly(glycerol sebacate) (PGS) as efficient dye adsorbents for wastewater treatment. The adsorbents showed high adsorption capacity and removal efficiency, making them suitable for purifying water solutions contaminated with water-soluble dyes.
Article
Polymer Science
Saba Seyfikar, Masoomeh Asgharnejad-laskoukalayeh, Seyed Hassan Jafari, Vahabodin Goodarzi, Mohammad Hadi Salehi, Soheila Zamanlui
Summary: A three-dimensional porous structure of poly(glycerol sebacate urethane) (PGSU) containing nanoclay and polyacrylic acid (PAAc) was successfully synthesized in this study. The particulate leaching technique using spun sugar as a porogen was employed for fabricating the porous structure. The viscoelastic behavior, hydrophilicity, and biocompatibility of the scaffolds were evaluated, indicating improved properties by incorporating nanoclay and PAAc. The feasibility of PGSU-based scaffolds for tissue engineering was confirmed through in vitro biocompatibility testing and significant cell adhesion in plasma-treated PGSU/PAAC/nanoclay.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Hadi Hosseini, Pegah Pirahmadi, Seyed Emadodin Shakeri, Ehsan Khoshbakhti, Sobhan Sharafkhani, Vafa Fakhri, Ardeshir Saeidi, David Julian McClements, Wei-Hsin Chen, Chia-Hung Su, Vahabodin Goodarzi
Summary: Eco-friendly nanocomposite aerogels with hydroxyapatite nanoparticles embedded in a polymer matrix were prepared and found to have a nanofibrous porous microstructure with a large surface area. These aerogels exhibited viscoelastic behavior and were effective at removing methylene blue from water through hydrogen bonding and electrostatic attraction. They also showed good reusability and may be useful for efficient removal of anionic pollutants.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Engineering, Biomedical
Hooman Golbaten-Mofrad, Mohammad Hadi Salehi, Seyed Hassan Jafari, Vahabodin Goodarzi, Maliheh Entezari, Mehrdad Hashemi
Summary: This study systematically investigates the influence of nanoclay and graphene oxide on the thermal, mechanical, hydrophobic, and biological properties of poly(glycerol sebacate)/gelatin nanocomposites. The results show that the appropriate dispersion of nanofillers improves the properties of the composites, but has a slight effect on mechanical properties. Additionally, the presence of nanofillers positively affects the biological performance of the composites.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2022)
Article
Materials Science, Biomaterials
Pardis Yousefi Talouki, Reyhaneh Tamimi, Soheila Zamanlui Benisi, Vahabodin Goodarzi, Shahrokh Shojaei, Saeed Hesami Tackalou, Hamid Reza Samadikhah
Summary: Elastomeric materials are valuable in meeting the needs of reconstructive medicine and tissue engineering. Poly glycerol sebacate (PGS) has shown potential in the medical industry, but it has poor mechanical properties. The use of composites and nanocomposites can improve the properties of PGS.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2023)
Article
Cell Biology
Masoumeh Heydari, Vahabodin Goodarzi, Mehdi Shams, Negar Motakef Kazemi, Ali Salimi
Summary: Tissue engineering involves the development and repair of functional and biological tissues using appropriate cells, engineering methods, and biochemical factors. This study focused on synthesizing a nanocomposite scaffold based on glycerol and azelaic acid combined with copper chromite nanoparticles to enhance the osteogenic differentiation of human adipose-derived stem cells (hADSCs). The properties of the nanocomposite scaffold, including degradability, hydrophobicity, mechanical strength, and thermal behaviors, were investigated. The cytotoxicity of the components was also evaluated. The results showed that the Gl-Az-1%CuCr2O4 nanocomposite scaffold exhibited suitable properties and promoted the osteogenic differentiation of hADSCs. This scaffold could be a promising candidate for bone regenerative medicine.
CELL AND TISSUE RESEARCH
(2023)
Article
Engineering, Biomedical
Vahid Faghihi-Rezaei, Hossein Ali Khonkdar, Vahabodin Goodarzi, Goldis Darbemamieh, Maryam Otadi
Summary: A series of 3D scaffolds based on PLA, TPU, and n-HA were prepared using the dual leaching technique. The interactions between the constituent materials were identified through Fourier-transform infrared spectroscopy analysis. The dual leaching technique proved to be effective in achieving the desired morphology and optimal dispersion and distribution of n-HA.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2023)
Article
Multidisciplinary Sciences
Zhila Ziaei-Rad, Mohammad Pazouki, Jamshid Fooladi, Mehrdad Azin, Sathyanarayana N. Gummadi, Abdollah Allahverdi
Summary: The cost-effective pretreatment of wheat straw using low-cost ionic liquid [TEA][HSO4] coupled with ultrasound irradiation was studied. The results showed that wheat straw pretreated at 130 degrees C for 15 and 30 min had high delignification rates of 67.8% and 74.9%, respectively, and hemicellulose removal rates of 47.0% and 52.2%. Enzymatic saccharification of the pretreated samples resulted in high saccharification yields of 67.7% and 79.8% and ethanol generation rates of 38.9 g/L and 42.0 g/L. This study demonstrated a promising and cost-effective pretreatment technology for bioethanol production.
SCIENTIFIC REPORTS
(2023)
Article
Biochemical Research Methods
Pardis Yousefi Talouki, Saeed Hesami Tackallou, Shahrokh Shojaei, Soheila Zamanlui Benisi, Vahabodin Goodarzi
Summary: This study aimed to evaluate the effects of Nanohydroxyapatite (nHA) on the chondrogenic differentiation of human adipose-derived mesenchymal stem cells (hADSCs) on polyglycerol sebacate (PGS) / polycaprolactone (PCL) / gelatin (Gel) scaffolds. The nHA nanocomposite scaffolds were characterized and tested for their hydrophilicity, degradation properties, and biocompatibility with hADSCs. The results showed that the nHA nanocomposite scaffolds promoted the differentiation of hADSCs into chondrocytes, making them a promising scaffold for cartilage tissue engineering.
BIOLOGICAL PROCEDURES ONLINE
(2023)
Correction
Biochemical Research Methods
Pardis Yousefi Talouki, Saeed Hesami Tackallou, Shahrokh Shojaei, Soheila Zamanlui Benisi, Vahabodin Goodarzi
BIOLOGICAL PROCEDURES ONLINE
(2023)
Article
Materials Science, Multidisciplinary
Pejman Ghaffari-Bohlouli, Hooman Golbaten-Mofrad, Najmeh Najmoddin, Vahabodin Goodarzi, Amin Shavandi, Wei-Hsin Chen
Summary: In this study, the electroconductivity, thermal stability, and mechanical properties of synthesized Poly (glycerol-sebacate-itaconic) (PGSIT) were investigated by incorporating polypyrrole (PPy) and clay within the PGSIT matrix. The addition of PPy and clay improved the conductivity, mechanical strength, and thermal stability of the PGSIT matrix. This PGSIT-PPy-clay composite shows potential as an electroconductive bio-elastomer for tissue engineering applications.
Article
Multidisciplinary Sciences
Shahin Ramazi, Mani Salimian, Abdollah Allahverdi, Shahla Kianamiri, Parviz Abdolmaleki
Summary: Breast cancer is a leading cause of cancer deaths in women worldwide. Magnetic fields have been found to have anti-tumor effects and can remotely affect cellular metabolism as a non-invasive therapy. Combining chemotherapy and magnetotherapy may be an effective treatment for breast cancer.
SCIENTIFIC REPORTS
(2023)
Review
Genetics & Heredity
Zahra Sahafnejad, Shahin Ramazi, Abdollah Allahverdi
Summary: Epigenetics is a significant field in biology that investigates changes in gene expression patterns not attributed to DNA sequence changes. Epigenetic marks, such as histone modifications, non-coding RNAs, and DNA methylation, play crucial roles in gene regulation. Aberrant epigenetic marks have been found to be associated with various diseases.
Article
Chemistry, Analytical
Hadi Hashemzadeh, Zahra Khadivi-Khanghah, Abdollah Allahverdi, Mohammad Mehdi Hadipour, Esmaiel Saievar-Iranizad, Hossein Naderi-Manesh
Summary: Conventional serological methods for detecting brucellosis are time-consuming and expensive, while new approaches are more sensitive. To improve detection, electrochemical nanostructured platforms, such as the graphene oxide nanowall-gold nanoflower platform, offer excellent electroactivity and antifouling properties, making them more sensitive than bare electrodes.
Article
Chemistry, Multidisciplinary
Vahid Faghihi-Rezaei, Hossein Ali Khonakdar, Vahabodin Goodarzi, Goldis Darbemamieh, Maryam Otadi
Summary: In this study, nanocomposites based on TPU and PLA were prepared using a solution method and hydroxyapatite nanoparticles were incorporated to enhance the properties of the alloys. Various tests were performed to investigate the properties of the nanocomposites. The results showed good dispersion of nanoparticles in the polymer matrix, negative effects of TPU and nanoparticles on crystalline properties, enhanced viscous behavior with TPU, increased elastic properties with nanoparticles, and significant improvement in mechanical properties with the addition of n-HA. The presence of TPU and n-HA led to changes in the interaction surface of the scaffolds. The findings suggest that the addition of n-HA into PLA/TPU blends could provide new features for tissue engineering applications.
GREEN PROCESSING AND SYNTHESIS
(2022)