Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration

Zebrafish facial lymphatics develop through sequential addition of venous and non‐venous progenitors

(2019) Tiffany CY Eng et al.   EMBO REPORTS

A Unique Collateral Artery Development Program Promotes Neonatal Heart Regeneration

(2019) Soumyashree Das et al.   CELL

Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development

(2019) Kazuaki Maruyama et al.   DEVELOPMENTAL BIOLOGY

Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium

(2019) Oliver A. Stone et al.   DEVELOPMENTAL CELL

A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development

(2018) Cathy Pichol-Thievend et al.   DEVELOPMENT

The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction

(2018) Joaquim Miguel Vieira et al.   JOURNAL OF CLINICAL INVESTIGATION

CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart

(2018) Fernando Bonet et al.   DEVELOPMENTAL DYNAMICS

Single-cell analysis of early progenitor cells that build coronary arteries

(2018) Tianying Su et al.   NATURE

Erythro-myeloid progenitors contribute endothelial cells to blood vessels

(2018) Alice Plein et al.   NATURE

Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish

(2018) Ravi Karra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac lymphatics in health and disease

(2018) Ebba Brakenhielm et al.   Nature Reviews Cardiology

Development and plasticity of meningeal lymphatic vessels

(2017) Salli Antila et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish

(2017) Neil I Bower et al.   NATURE NEUROSCIENCE

Cardiac Lymphatics – A New Avenue for Therapeutics?

(2017) Taina Vuorio et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta

(2017) Lyad Zamir et al.   eLife

Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development

(2017) Max van Lessen et al.   eLife

Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1

(2017) Sawan Kumar Jha et al.   Scientific Reports

Autotaxin–Lysophosphatidic Acid Axis Acts Downstream of Apoprotein B Lipoproteins in Endothelial CellsHighlights

(2016) Liron Gibbs-Bar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heterogeneity in the lymphatic vascular system and its origin

(2016) Maria H. Ulvmar et al.   CARDIOVASCULAR RESEARCH

Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial InfarctionCLINICAL PERSPECTIVE

(2016) Orianne Henri et al.   CIRCULATION

Development of the lymphatic system: new questions and paradigms

(2016) Jonathan Semo et al.   DEVELOPMENT

Fast revascularization of the injured area is essential to support zebrafish heart regeneration

(2016) Rubén Marín-Juez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radial glia regulate vascular patterning around the developing spinal cord

(2016) Ryota L Matsuoka et al.   eLife

Lymphatic Vessels at the Heart of the Matter

(2015) Veronique Angeli et al.   Cell Metabolism

Nonvenous Origin of Dermal Lymphatic Vasculature

(2015) I. Martinez-Corral et al.   CIRCULATION RESEARCH

Anatomy and development of the cardiac lymphatic vasculature: Its role in injury and disease

(2015) Sophie Norman et al.   CLINICAL ANATOMY

The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development

(2015) Sarah Ivins et al.   DEVELOPMENTAL CELL

Chemokine-Guided Angiogenesis Directs Coronary Vasculature Formation in Zebrafish

(2015) Michael R.M. Harrison et al.   DEVELOPMENTAL CELL

Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

(2015) Fatma O. Kok et al.   DEVELOPMENTAL CELL

A new heart for a new head in vertebrate cardiopharyngeal evolution

(2015) Rui Diogo et al.   NATURE

Cardiac lymphatics are heterogeneous in origin and respond to injury

(2015) Linda Klotz et al.   NATURE

Lymphatic vessels arise from specialized angioblasts within a venous niche

(2015) J. Nicenboim et al.   NATURE

Genetic targeting of sprouting angiogenesis using Apln-CreER

(2015) Qiaozhen Liu et al.   Nature Communications

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

(2015) Lukas Stanczuk et al.   Cell Reports

Advanced Echocardiography in Adult Zebrafish Reveals Delayed Recovery of Heart Function after Myocardial Cryoinjury

(2015) Selina J. Hein et al.   PLoS One

Cardiac Mouse Lymphatics: Developmental and Anatomical Update

(2014) Aleksandra Flaht-Zabost et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis

(2014) H. I. Chen et al.   DEVELOPMENT

Divergence of zebrafish and mouse lymphatic cell fate specification pathways

(2014) A. van Impel et al.   DEVELOPMENT

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis

(2014) L. Le Guen et al.   DEVELOPMENT

Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting

(2014) J. W. Astin et al.   DEVELOPMENT

The Left-Right Pitx2 Pathway Drives Organ-Specific Arterial and Lymphatic Development in the Intestine

(2014) Aparna Mahadevan et al.   DEVELOPMENTAL CELL

VEGF-C and aortic cardiomyocytes guide coronary artery stem development

(2014) Heidi I. Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

An Injury-Responsive Gata4 Program Shapes the Zebrafish Cardiac Ventricle

(2013) Vikas Gupta et al.   CURRENT BIOLOGY

A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development

(2013) J. A. Villefranc et al.   DEVELOPMENT

Notch controls retinal blood vessel maturation and quiescence

(2013) M. Ehling et al.   DEVELOPMENT

Haemogenic endocardium contributes to transient definitive haematopoiesis

(2013) Haruko Nakano et al.   Nature Communications

Endocardial Cells Form the Coronary Arteries by Angiogenesis through Myocardial-Endocardial VEGF Signaling

(2012) Bingruo Wu et al.   CELL

Migration of cardiomyocytes is essential for heart regeneration in zebrafish

(2012) J. Itou et al.   DEVELOPMENT

lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish

(2012) K. S. Okuda et al.   DEVELOPMENT

Chemokine Signaling Directs Trunk Lymphatic Network Formation along the Preexisting Blood Vasculature

(2012) Young Ryun Cha et al.   DEVELOPMENTAL CELL

ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1

(2012) Inbal Avraham-Davidi et al.   NATURE MEDICINE

CCBE1 Is Essential for Mammalian Lymphatic Vascular Development and Enhances the Lymphangiogenic Effect of Vascular Endothelial Growth Factor-C In Vivo

(2011) Frank L. Bos et al.   CIRCULATION RESEARCH

Assembly and patterning of the vascular network of the vertebrate hindbrain

(2011) M. Fujita et al.   DEVELOPMENT

Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling

(2011) J. Bussmann et al.   DEVELOPMENT

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

(2011) J. M. Gonzalez-Rosa et al.   DEVELOPMENT

A Computational Tool for Quantitative Analysis of Vascular Networks

(2011) Enrique Zudaire et al.   PLoS One

Lymphatic ontogeny and effect of hypoplasia in developing lung

(2010) Rishikesh M. Kulkarni et al.   MECHANISMS OF DEVELOPMENT

Coronary arteries form by developmental reprogramming of venous cells

(2010) Kristy Red-Horse et al.   NATURE

Normal table of postembryonic zebrafish development: Staging by externally visible anatomy of the living fish

(2009) David M. Parichy et al.   DEVELOPMENTAL DYNAMICS

Chemokine signaling guides regional patterning of the first embryonic artery

(2009) A. F. Siekmann et al.   GENES & DEVELOPMENT

ccbe1 is required for embryonic lymphangiogenesis and venous sprouting

(2009) Benjamin M Hogan et al.   NATURE GENETICS

Cardiac Hypertrophy Involves Both Myocyte Hypertrophy and Hyperplasia in Anemic Zebrafish

(2009) Xiaojing Sun et al.   PLoS One

Retro-orbital Injection in Adult Zebrafish

(2009) Emily K. Pugach et al.   Jove-Journal of Visualized Experiments

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell