Non-enzymatic primer extension with strand displacement

Periodic Melting of Oligonucleotides by Oscillating Salt Concentrations triggered by Microscale Water Cycles inside Heated Rock Pores

(2019) Dieter Braun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonenzymatic Template-Directed Synthesis of Mixed-Sequence 3′-NP-DNA up to 25 Nucleotides Long Inside Model Protocells

(2019) Derek K. O’Flaherty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme-Free Replication with Two or Four Bases

(2018) Elena Hänle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copying of Mixed-Sequence RNA Templates inside Model Protocells

(2018) Derek K. O’Flaherty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Light-Releasable Potentially Prebiotic Nucleotide Activating Agent

(2018) Angelica Mariani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystallographic observation of nonenzymatic RNA primer extension

(2018) Wen Zhang et al.   eLife

Protocells and RNA Self-Replication

(2018) Gerald F. Joyce et al.   Cold Spring Harbor Perspectives in Biology

pH-Driven RNA Strand Separation under Prebiotically Plausible Conditions

(2018) Angelica Mariani et al.   BIOCHEMISTRY

Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA

(2018) Seohyun Chris Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation

(2017) Albert C. Fahrenbach et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides

(2017) Li Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A simple physical mechanism enables homeostasis in primitive cells

(2016) Aaron E. Engelhart et al.   Nature Chemistry

A viscous solvent enables information transfer from gene-length nucleic acids in a model prebiotic replication cycle

(2016) Christine He et al.   Nature Chemistry

A general strategy for expanding polymerase function by droplet microfluidics

(2016) Andrew C. Larsen et al.   Nature Communications

Nonenzymatic copying of RNA templates containing all four letters is catalyzed by activated oligonucleotides

(2016) Noam Prywes et al.   eLife

Replacing Uridine with 2-Thiouridine Enhances the Rate and Fidelity of Nonenzymatic RNA Primer Extension

(2015) Benjamin D. Heuberger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Spinach molecular beacon triggered by strand displacement

(2014) Sanchita Bhadra et al.   RNA

Fast and accurate nonenzymatic copying of an RNA-like synthetic genetic polymer

(2013) S. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis of N3′-P5′-linked Phosphoramidate DNA by Nonenzymatic Template-Directed Primer Extension

(2012) Shenglong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic DNA nanotechnology using strand-displacement reactions

(2011) David Yu Zhang et al.   Nature Chemistry

Effect of Stalling after Mismatches on the Error Catastrophe in Nonenzymatic Nucleic Acid Replication

(2010) Sudha Rajamani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY