TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice

Direction Selectivity in Drosophila Proprioceptors Requires the Mechanosensory Channel Tmc

(2019) Liping He et al.   CURRENT BIOLOGY

TMC Proteins Modulate Egg Laying and Membrane Excitability through a Background Leak Conductance in C. elegans

(2018) Xiaomin Yue et al.   NEURON

Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea

(2018) Maryline Beurg et al.   Nature Communications

TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells

(2018) Bifeng Pan et al.   NEURON

Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins

(2018) Angela Ballesteros et al.   eLife

Phosphoinositol-4,5-Bisphosphate Regulates Auditory Hair-Cell Mechanotransduction-Channel Pore Properties and Fast Adaptation

(2017) Thomas Effertz et al.   JOURNAL OF NEUROSCIENCE

TMC2 Modifies Permeation Properties of the Mechanoelectrical Transducer Channel in Early Postnatal Mouse Cochlear Outer Hair Cells

(2017) Laura F. Corns et al.   Frontiers in Molecular Neuroscience

Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells

(2016) L. F. Corns et al.   JOURNAL OF NEUROSCIENCE

Molecular Identity of the Mechanotransduction Channel in Hair Cells: Not Quiet There Yet

(2016) Z. Wu et al.   JOURNAL OF NEUROSCIENCE

Are TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?

(2016) D. P. Corey et al.   JOURNAL OF NEUROSCIENCE

TMC-1 Mediates Alkaline Sensation in C. elegans through Nociceptive Neurons

(2016) Xiang Wang et al.   NEURON

The Basis of Food Texture Sensation in Drosophila

(2016) Yali V. Zhang et al.   NEURON

Transmembrane channel-like (tmc) gene regulatesDrosophilalarval locomotion

(2016) Yanmeng Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects ofTmc1 Beethovenmutation on mechanotransducer channel function in cochlear hair cells

(2015) Maryline Beurg et al.   JOURNAL OF GENERAL PHYSIOLOGY

TMC-1 attenuates C. elegans development and sexual behaviour in a chemically defined food environment

(2015) Liusuo Zhang et al.   Nature Communications

TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia

(2015) Kiyoto Kurima et al.   Cell Reports

Conductance and block of hair-cell mechanotransducer channels in transmembrane channel–like protein mutants

(2014) Maryline Beurg et al.   JOURNAL OF GENERAL PHYSIOLOGY

Using injectoporation to deliver genes to mechanosensory hair cells

(2014) Wei Xiong et al.   Nature Protocols

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

(2014) Yoshiyuki Kawashima et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Subunit determination of the conductance of hair-cell mechanotransducer channels

(2014) Maryline Beurg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells

(2014) L. F. Corns et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TMC1 and TMC2 Are Components of the Mechanotransduction Channel in Hair Cells of the Mammalian Inner Ear

(2013) Bifeng Pan et al.   NEURON

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2012) Wei Xiong et al.   CELL

Developmental changes in the cochlear hair cell mechanotransducer channel and their regulation by transmembrane channel–like proteins

(2012) Kyunghee X. Kim et al.   JOURNAL OF GENERAL PHYSIOLOGY

The Resting Transducer Current Drives Spontaneous Activity in Prehearing Mammalian Cochlear Inner Hair Cells

(2012) S. L. Johnson et al.   JOURNAL OF NEUROSCIENCE

Cardiac Sarcoplasmic Reticulum Calcium Leak: Basis and Roles in Cardiac Dysfunction

(2011) Donald M. Bers   Annual Review of Physiology

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

(2011) Yoshiyuki Kawashima et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels

(2010) Péter Enyedi et al.   PHYSIOLOGICAL REVIEWS