IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP

Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection

(2019) Philipp E. Merkl et al.   mBio

Mechanisms of Host IFI16, PML, and Daxx Protein Restriction of Herpes Simplex Virus 1 Replication

(2018) Philipp E. Merkl et al.   JOURNAL OF VIROLOGY

Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency

(2018) Sharon E. Hopcraft et al.   PLoS Pathogens

The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression

(2017) Sreya Ghosh et al.   JOURNAL OF IMMUNOLOGY

Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma Tissues

(2017) Rui Sun et al.   PLoS Pathogens

Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency

(2016) Arunava Roy et al.   JOURNAL OF VIROLOGY

H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes

(2016) Justin S. Becker et al.   TRENDS IN GENETICS

LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection

(2016) Zsolt Toth et al.   PLoS Pathogens

Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses

(2016) Jawed Iqbal et al.   PLoS Pathogens

The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human Papillomavirus Replication through Epigenetic Modifications of the Viral Promoters

(2015) Irene Lo Cigno et al.   JOURNAL OF VIROLOGY

Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses

(2015) Mairaj Ahmed Ansari et al.   PLoS Pathogens

BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses

(2015) Dipanjan Dutta et al.   PLoS Pathogens

Differential Regulation of Estrogen Receptor   Expression in Breast Cancer Cells by Metastasis-Associated Protein 1

(2014) H.-J. Kang et al.   CANCER RESEARCH

Interferon γ-inducible Protein (IFI) 16 Transcriptionally Regulates Type I Interferons and Other Interferon-stimulated Genes and Controls the Interferon Response to both DNA and RNA Viruses

(2014) Mikayla R. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HP1a: a structural chromosomal protein regulating transcription

(2014) Joel C. Eissenberg et al.   TRENDS IN GENETICS

Influence of ND10 Components on Epigenetic Determinants of Early KSHV Latency Establishment

(2014) Thomas Günther et al.   PLoS Pathogens

IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

(2014) Karen E. Johnson et al.   PLoS Pathogens

Constitutive Interferon-Inducible Protein 16-Inflammasome Activation during Epstein-Barr Virus Latency I, II, and III in B and Epithelial Cells

(2013) M. A. Ansari et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus Latency in Endothelial and B Cells Activates Gamma Interferon-Inducible Protein 16-Mediated Inflammasomes

(2013) V. V. Singh et al.   JOURNAL OF VIROLOGY

Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA

(2013) M. H. Orzalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Chromatin Landscape of Kaposi’s Sarcoma-Associated Herpesvirus

(2013) Zsolt Toth et al.   Viruses-Basel

Biphasic Euchromatin-to-Heterochromatin Transition on the KSHV Genome Following De Novo Infection

(2013) Zsolt Toth et al.   PLoS Pathogens

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

(2012) Tengchuan Jin et al.   IMMUNITY

Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line

(2012) Michael Stürzl et al.   INTERNATIONAL JOURNAL OF CANCER

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Interacts with Multifunctional Angiogenin To Utilize Its Antiapoptotic Functions

(2012) N. Paudel et al.   JOURNAL OF VIROLOGY

The Intracellular DNA Sensor IFI16 Gene Acts as Restriction Factor for Human Cytomegalovirus Replication

(2012) Grazia Rosaria Gariano et al.   PLoS Pathogens

IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection

(2011) Nagaraj Kerur et al.   Cell Host & Microbe

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induction by Hypoxia and Hypoxia-Inducible Factors

(2011) R. P. Veeranna et al.   JOURNAL OF VIROLOGY

Interferon-Inducible Protein 16: Insight into the Interaction with Tumor Suppressor p53

(2011) Jack C.C. Liao et al.   STRUCTURE

Epigenetic regulation of latent HSV-1 gene expression

(2010) David C. Bloom et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A Subset of the Histone H3 Lysine 9 Methyltransferases Suv39h1, G9a, GLP, and SETDB1 Participate in a Multimeric Complex

(2010) Lauriane Fritsch et al.   MOLECULAR CELL

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Epigenetic Analysis of KSHV Latent and Lytic Genomes

(2010) Zsolt Toth et al.   PLoS Pathogens

The Epigenetic Landscape of Latent Kaposi Sarcoma-Associated Herpesvirus Genomes

(2010) Thomas Günther et al.   PLoS Pathogens

Transcription of the Herpes Simplex Virus Latency-Associated Transcript Promotes the Formation of Facultative Heterochromatin on Lytic Promoters

(2009) A. R. Cliffe et al.   JOURNAL OF VIROLOGY

Role of IFI16 in DNA damage and checkpoint

(2007) Mutsuko Ouchi   Frontiers in Bioscience-Landmark