A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment

LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency

(2019) Alessandra De Leo et al.   PLoS Pathogens

Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation

(2019) Anne Laugesen et al.   MOLECULAR CELL

The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells

(2018) Gundula Streubel et al.   MOLECULAR CELL

MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding

(2018) Matteo Perino et al.   NATURE GENETICS

In vivo persistence of chimeric virus after substitution of the KSHV LANA DNA binding domain with that of MuHV-4

(2018) Marta Pires de Miranda et al.   JOURNAL OF VIROLOGY

Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency

(2018) Sharon E. Hopcraft et al.   PLoS Pathogens

Murine Gammaherpesvirus 68 Expressing Kaposi Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen (LANA) Reveals both Functional Conservation and Divergence in LANA Homologs

(2017) Arundhati Gupta et al.   JOURNAL OF VIROLOGY

Polycomb-like proteins link the PRC2 complex to CpG islands

(2017) Haojie Li et al.   NATURE

DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation

(2017) Jeongyoon Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation

(2017) Jeongyoon Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cross-species conservation of episome maintenance provides a basis for in vivo investigation of Kaposi's sarcoma herpesvirus LANA

(2017) Aline C. Habison et al.   PLoS Pathogens

Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma Tissues

(2017) Rui Sun et al.   PLoS Pathogens

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy

(2016) Dirk P. Dittmer et al.   JOURNAL OF CLINICAL INVESTIGATION

An interactive environment for agile analysis and visualization of ChIP-sequencing data

(2016) Mads Lerdrup et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An interactive environment for agile analysis and visualization of ChIP-sequencing data

(2016) Mads Lerdrup et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection

(2016) Zsolt Toth et al.   PLoS Pathogens

Kaposi’s Sarcoma Herpesvirus Genome Persistence

(2016) Franceline Juillard et al.   Frontiers in Microbiology

Recruiting polycomb to chromatin

(2015) Ila van Kruijsbergen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis

(2015) Thomas F Schulz et al.   Current Opinion in Virology

A simple method for generating high-resolution maps of genome-wide protein binding

(2015) Peter J Skene et al.   eLife

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

(2014) Neil P. Blackledge et al.   CELL

Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide

(2014) Eva Madi Riising et al.   MOLECULAR CELL

Ruled by Ubiquitylation: A New Order for Polycomb Recruitment

(2014) Yuri B. Schwartz et al.   Cell Reports

Influence of ND10 Components on Epigenetic Determinants of Early KSHV Latency Establishment

(2014) Thomas Günther et al.   PLoS Pathogens

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

The Open Chromatin Landscape of Kaposi's Sarcoma-Associated Herpesvirus

(2013) I. B. Hilton et al.   JOURNAL OF VIROLOGY

Fbxl10/Kdm2b Recruits Polycomb Repressive Complex 1 to CpG Islands and Regulates H2A Ubiquitylation

(2013) Xudong Wu et al.   MOLECULAR CELL

Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes

(2013) Jin He et al.   NATURE CELL BIOLOGY

Biphasic Euchromatin-to-Heterochromatin Transition on the KSHV Genome Following De Novo Infection

(2013) Zsolt Toth et al.   PLoS Pathogens

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone

(2012) Kevin F. Brulois et al.   JOURNAL OF VIROLOGY

Murine Gammaherpesvirus 68 LANA Acts on Terminal Repeat DNA To Mediate Episome Persistence

(2012) A. C. Habison et al.   JOURNAL OF VIROLOGY

Tiled Microarray Identification of Novel Viral Transcript Structures and Distinct Transcriptional Profiles during Two Modes of Productive Murine Gammaherpesvirus 68 Infection

(2012) Benson Yee Hin Cheng et al.   JOURNAL OF VIROLOGY

Tracking Murine Gammaherpesvirus 68 Infection of Germinal Center B Cells In Vivo

(2012) Christopher M. Collins et al.   PLoS One

Unbiased Mutagenesis of MHV68 LANA Reveals a DNA-Binding Domain Required for LANA Function In Vitro and In Vivo

(2012) Clinton R. Paden et al.   PLoS Pathogens

KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

(2012) Anca M Farcas et al.   eLife

Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon induction

(2011) Jinjong Myoung et al.   JOURNAL OF VIROLOGICAL METHODS

Epigenetic Analysis of KSHV Latent and Lytic Genomes

(2010) Zsolt Toth et al.   PLoS Pathogens

The Epigenetic Landscape of Latent Kaposi Sarcoma-Associated Herpesvirus Genomes

(2010) Thomas Günther et al.   PLoS Pathogens

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

(2009) Chongzhi Zang et al.   BIOINFORMATICS

RTA Promoter Demethylation and Histone Acetylation Regulation of Murine Gammaherpesvirus 68 Reactivation

(2009) Zhangsheng Yang et al.   PLoS One

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Alternatively Initiated Gene 50/RTA Transcripts Expressed during Murine and Human Gammaherpesvirus Reactivation from Latency

(2008) K. S. Gray et al.   JOURNAL OF VIROLOGY

A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis

(2008) Kristoffer Weber et al.   MOLECULAR THERAPY

The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b

(2008) Jin He et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY