SorCS1-mediated sorting in dendrites maintains neurexin axonal surface polarization required for synaptic function

SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology

(2019) Anna R. Malik et al.   Cell Reports

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways

(2019) Xiaoting Wu et al.   NEURON

Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses

(2019) Jinye Dai et al.   NEURON

SORCS1 and SORCS3 control energy balance and orexigenic peptide production

(2018) Aygul Subkhangulova et al.   EMBO REPORTS

Trafficking mechanisms of synaptogenic cell adhesion molecules

(2018) Luís F. Ribeiro et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A Modular Organization of LRR Protein-Mediated Synaptic Adhesion Defines Synapse Identity

(2018) Anna Schroeder et al.   NEURON

Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties

(2017) Soham Chanda et al.   JOURNAL OF NEUROSCIENCE

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins

(2017) Lulu Y. Chen et al.   NEURON

Retrograde Synaptic Inhibition Is Mediated by α-Neurexin Binding to the α2δ Subunits of N-Type Calcium Channels

(2017) Xia-Jing Tong et al.   NEURON

SorCS2 is required for BDNF-dependent plasticity in the hippocampus

(2016) S Glerup et al.   MOLECULAR PSYCHIATRY

The cellular mechanisms that maintain neuronal polarity

(2016) Marvin Bentley et al.   NATURE REVIEWS NEUROSCIENCE

Two Clathrin Adaptor Protein Complexes Instruct Axon-Dendrite Polarity

(2016) Pengpeng Li et al.   NEURON

Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer’s Disease Mutations

(2016) Grace Woodruff et al.   Cell Reports

β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling

(2015) Garret R. Anderson et al.   CELL

SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport

(2015) Guido Hermey et al.   JOURNAL OF NEUROCHEMISTRY

Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals

(2015) Christian Neupert et al.   JOURNAL OF NEUROSCIENCE

The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors

(2015) Jeffrey N. Savas et al.   NEURON

Sorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone

(2015) Ginny G. Farías et al.   Cell Reports

Quantitative isoform-profiling of highly diversified recognition molecules

(2015) Dietmar Schreiner et al.   eLife

Analysis of copy number variations at 15 schizophrenia-associated loci

(2013) Elliott Rees et al.   BRITISH JOURNAL OF PSYCHIATRY

Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation

(2013) O. Gokce et al.   JOURNAL OF NEUROSCIENCE

Differential regulation of neurexin at glutamatergic and GABAergic synapses

(2013) Giulia Pregno et al.   Frontiers in Cellular Neuroscience

Evolution of Synapse Complexity and Diversity

(2012) Richard D. Emes et al.   Annual Review of Neuroscience

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

Synchronization of secretory protein traffic in populations of cells

(2012) Gaelle Boncompain et al.   NATURE METHODS

Neurexin and Neuroligin Mediate Retrograde Synaptic Inhibition in C. elegans

(2012) Z. Hu et al.   SCIENCE

Rare Deletions at the Neurexin 3 Locus in Autism Spectrum Disorder

(2011) Andrea K. Vaags et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia

(2011) Julie Gauthier et al.   HUMAN GENETICS

Rare Copy Number Variation Discovery and Cross-Disorder Comparisons Identify Risk Genes for ADHD

(2011) A. C. Lionel et al.   Science Translational Medicine

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk

(2010) Christiane Reitz et al.   ANNALS OF NEUROLOGY

Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-  Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex

(2010) R. F. Lane et al.   JOURNAL OF NEUROSCIENCE

Convergence of linkage, association and GWAS findings for a candidate region for bipolar disorder and schizophrenia on chromosome 4p

(2010) A Christoforou et al.   MOLECULAR PSYCHIATRY

A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor

(2010) Tao Su et al.   NATURE CELL BIOLOGY

Differential dynamics and activity-dependent regulation of  - and  -neurexins at developing GABAergic synapses

(2010) Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking Guidance Receptors

(2010) B. Winckler et al.   Cold Spring Harbor Perspectives in Biology

The dynamic Rab11-FIPs

(2009) Conor P. Horgan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Vps10p-domain receptor family

(2009) Guido Hermey   CELLULAR AND MOLECULAR LIFE SCIENCES

Axonal targeting of Caspr2 in hippocampal neurons via selective somatodendritic endocytosis

(2009) C. Bel et al.   JOURNAL OF CELL SCIENCE

Axonal Targeting of Trk Receptors via Transcytosis Regulates Sensitivity to Neurotrophin Responses

(2009) M. Ascano et al.   JOURNAL OF NEUROSCIENCE

Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort

(2009) H M Ollila et al.   MOLECULAR PSYCHIATRY

Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses

(2009) Jooyeon Woo et al.   NATURE NEUROSCIENCE

Regulation of AMPA receptor extrasynaptic insertion by 4.1N, phosphorylation and palmitoylation

(2009) Da-Ting Lin et al.   NATURE NEUROSCIENCE

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

(2009) Robert H Kutner et al.   Nature Protocols

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM

(2008) Chan Choo Yap et al.   JOURNAL OF CELL BIOLOGY

The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling

(2008) E. Schonteich et al.   JOURNAL OF CELL SCIENCE

Polarized Targeting of Neurexins to Synapses Is Regulated by their C-Terminal Sequences

(2008) R. Fairless et al.   JOURNAL OF NEUROSCIENCE

Developmental Control of Synaptic Receptivity

(2008) A. J. Barker et al.   JOURNAL OF NEUROSCIENCE

VPS10P-domain receptors — regulators of neuronal viability and function

(2008) Thomas E. Willnow et al.   NATURE REVIEWS NEUROSCIENCE

Different Motifs Regulate Trafficking of SorCS1 Isoforms

(2008) Morten S. Nielsen et al.   TRAFFIC