Article
Environmental Sciences
Kexin Yu, Qingli Zhang, Xia Meng, Lina Zhang, Haidong Kan, Renjie Chen
Summary: This study found that long-term residential exposure to greenness is associated with a lower risk of incident chronic obstructive pulmonary disease (COPD) among UK adults. The association is partially mediated by physical activity, PM2.5, and NOx. These findings provide support for greening policies in respiratory health promotion efforts.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Nutrition & Dietetics
Xinglin Wan, Lulu Chen, Zheng Zhu, Pengfei Luo, Dong Hang, Jian Su, Ran Tao, Jinyi Zhou, Xikang Fan
Summary: Hypercalcemia is positively associated with the risk of COPD incidence and mortality in the European population, suggesting a potential impact of serum calcium on the progression of COPD.
Article
Endocrinology & Metabolism
Mengyao Li, Yanan Wan, Zheng Zhu, Pengfei Luo, Hao Yu, Jian Su, Dong Hang, Yan Lu, Ran Tao, Ming Wu, Jinyi Zhou, Xikang Fan
Summary: This study investigated the association between glycated haemoglobin (HbA1c) levels and the incidence of chronic obstructive pulmonary disease (COPD) in the general population, as well as the association between HbA1c levels and mortality in patients with COPD. The results showed that both lower and higher HbA1c levels were associated with an increased risk of COPD and all-cause death in COPD patients.
DIABETES OBESITY & METABOLISM
(2023)
Article
Biochemistry & Molecular Biology
Qida He, Mengtong Sun, Hanqing Zhao, Na Sun, Qiang Han, Zhaolong Feng, Tongxing Li, Yu Wang, Guoxian Li, Ze Ma, Xiaoqin Liu, Yueping Shen
Summary: This study found that high consumption of ultra-processed food (UPF) is associated with an increased risk of chronic obstructive pulmonary disease (COPD), and this association is mediated by biomarkers related to glucose, inflammation, and lipids. Substituting UPF with unprocessed or minimally processed food (UNPF) can decrease the risk of COPD.
Article
Biochemistry & Molecular Biology
Qida He, Mengtong Sun, Hanqing Zhao, Na Sun, Qiang Han, Zhaolong Feng, Tongxing Li, Yu Wang, Guoxian Li, Ze Ma, Xiaoqin Liu, Yueping Shen
Summary: This study found that consuming a high amount of ultra-processed food (UPF) is associated with an increased risk of chronic obstructive pulmonary disease (COPD), and this association is primarily mediated by glucose, inflammation, and lipids.
Article
Endocrinology & Metabolism
Jian Su, Mengyao Li, Xinglin Wan, Hao Yu, Yanan Wan, Dong Hang, Yan Lu, Ran Tao, Ming Wu, Jinyi Zhou, Xikang Fan
Summary: This study finds that diabetes, prediabetes, and longer diabetes duration are associated with a higher risk of and worse survival for chronic obstructive pulmonary disease (COPD).
DIABETES OBESITY & METABOLISM
(2023)
Article
Respiratory System
Sara De Matteis, Debbie Jarvis, Lucy Darnton, Dario Consonni, Hans Kromhout, Sally Hutchings, Steven S. Sadhra, David Fishwick, Roel Vermeulen, Lesley Rushton, Paul Cullinan
Summary: This large population-based study found an association between occupational exposure to pesticides and risk of COPD. The risk was particularly pronounced among non-smokers and individuals without asthma.
Article
Respiratory System
Zheng Zhu, Xinglin Wan, Jiannan Liu, Dandan Zhang, Pengfei Luo, Wencong Du, Lulu Chen, Jian Su, Dong Hang, Jinyi Zhou, Xikang Fan
Summary: This study investigated the associations of serum 25-hydroxyvitamin D (25(OH)D) concentrations with the risk and survival of chronic obstructive pulmonary disease (COPD). The results showed a non-linear inverse association between 25(OH)D concentrations and the incidence and mortality of COPD, suggesting a potential protective role of vitamin D in the pathogenesis of COPD.
BMJ OPEN RESPIRATORY RESEARCH
(2023)
Article
Endocrinology & Metabolism
Shiwen Li, Tingjing Zhang, Honghao Yang, Qing Chang, Yuhong Zhao, Liangkai Chen, Li Zhao, Yang Xia
Summary: Metabolic syndrome and genetic predisposition have an impact on the risk of developing chronic obstructive pulmonary disease (COPD), with individuals with MetS being at higher risk and those with high genetic predisposition having an increased risk. However, there is no significant interaction between MetS and genetic risk in relation to COPD risk.
DIABETES OBESITY & METABOLISM
(2023)
Article
Cardiac & Cardiovascular Systems
Fang Zhu, Hongchao Qi, Maxime Bos, Eric Boersma, Maryam Kavousi
Summary: This study found that female reproductive history is associated with the risk of heart failure, particularly with younger age at menarche, younger age at menopause, younger maternal age at first and last live birth, and having a higher number of children.
JACC-HEART FAILURE
(2023)
Article
Critical Care Medicine
Vanesa Bellou, Lazaros Belbasis, Evangelos Evangelou
Summary: The study revealed an association between smoking and the risk of IPF, with a dose-response relationship observed between pack-years of smoking and IPF risk. Maternal smoking was also associated with IPF risk, and additive and multiplicative interactions were observed between maternal smoking and smoking status.
Article
Dentistry, Oral Surgery & Medicine
Dongyun Wang, Liang Dai, Zhengqian Cui, Weili Xing, Xiaoyan Huang, Hongyu Yang, Ying Shan
Summary: This study investigates the association between periodontal diseases and airflow limitation, as well as incident chronic obstructive pulmonary disease (COPD). The results suggest that periodontal diseases are significantly associated with airflow limitation and an increased risk of COPD incidence. This association remains consistent across different subgroups.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Medicine, General & Internal
Hamish M. E. Foster, Jason M. R. Gill, Frances S. Mair, Carlos A. Celis-Morales, Bhautesh D. Jani, Barbara I. Nicholl, Duncan Lee, Catherine A. O'Donnell
Summary: This study found that both functional and structural components of social connection are independently associated with mortality. It also suggests that the beneficial associations for some types of social connection might not be felt when other types of social connection are absent. Additionally, individuals who live alone with additional structural markers of isolation may represent a high-risk population.
Article
Biology
Ardalan Naseri, Kecong Tang, Xin Geng, Junjie Shi, Jing Zhang, Pramesh Shakya, Xiaoming Liu, Shaojie Zhang, Degui Zhi
Summary: This study conducted an individual-centric analysis of IBD segments among the UK Biobank participants, revealing genetic makeup, personal genealogical history, and social behavior characteristics of individuals with important genetic connections at the population scale, opening possibilities for further studies of individual's genetic connections in biobank data.
Article
Nutrition & Dietetics
Camilla Barbero Mazzucca, Lorenza Scotti, Giuseppe Cappellano, Francesco Barone-Adesi, Annalisa Chiocchetti
Summary: This study investigates the relationship between nutrition and the risk of Rheumatoid arthritis (RA) using a large sample size. The results suggest that oily fish, alcohol, coffee, and breakfast cereals have protective roles in RA, while tea may increase the risk of RA onset.
Article
Psychology, Clinical
Lucy Hiscox, Sidney Bray, Abigail Fraser, Richard Meiser-Stedman, Soraya Seedat, Sarah L. Halligan
Summary: Higher levels of PTSD symptoms are present among trauma-exposed females compared to males in adulthood. However, little is known about the emergence of this sex difference during development. This study found that sex differences in PTSD symptoms become apparent during adolescence, with females showing more significant symptom reduction at the age of 13.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Family Studies
Rachel M. Hiller, Abigail Fraser, Megan Denne, Andreas Bauer, Sarah L. Halligan
Summary: Although there is limited evidence on the longitudinal development of mental health difficulties among young people in out-of-home care, it has been found that entering the care system is not enough for natural recovery from these issues. The number of placements and separation from siblings are associated with greater difficulties.
CHILD MALTREATMENT
(2023)
Article
Criminology & Penology
Annie Herbert, Abigail Fraser, Laura D. Howe, Eszter Szilassy, Maria Barnes, Gene Feder, Christine Barter, Jon Heron
Summary: In this study, categories of different types and frequencies of IPVA victimization were found to be associated with differential rates of negative impact and perpetration. This is consistent with emerging evidence of IPVA differentiation and its variable impact in other populations.
JOURNAL OF INTERPERSONAL VIOLENCE
(2023)
Review
Obstetrics & Gynecology
Danya Bakhbakhi, Dimitrios Siassakos, Anna Davies, Abi Merriel, Katie Barnard, Emma Stead, Clare Shakespeare, James M. N. Duffy, Lisa Hinton, Karolina McDowell, Anna Lyons, Abigail Fraser, Christy Burden, iCHOOSE Collaborat Grp
Summary: The research on interventions after stillbirth diagnosis lacks consistent outcome reporting and evidence improvement. The establishment of a core outcome set is necessary for standardizing outcome collection and reporting in stillbirth care research.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Multidisciplinary Sciences
Helena D. Urquijo, Ana Goncalves R. Soares, Abigail Fraser, Laura Howe, Alice Carter
Summary: Cardiovascular disease is influenced by genetics and environment. Childhood maltreatment is associated with cardiovascular disease and may modify genetic susceptibility. This study found that childhood maltreatment accentuated the effect of genetic susceptibility to higher BMI.
Article
Multidisciplinary Sciences
Emily M. Frier, Chun Lin, Rebecca M. Reynolds, Karel Allegaert, Jasper Been, Abigail Fraser, Mika P. Gissler, Kristjana Einarsdottir, Lani Florian, Bo Jacobsson, Joshua Vogel, Helga Zoega, Sohinee Bhattacharya, Eyal Krispin, Lars Henning Pedersen, Devender Roberts, Stefan Kuhle, John Fahey, Ben W. Mol, David Burgner, Ewoud Schuit, Aziz Sheikh, Rachael Wood, Cynthia Gyamfi-Bannerman, Jessica E. Miller, Kate Duhig, Marius Lahti-Pulkkinen, Eran Hadar, John Wright, Sarah R. Murray, Sarah J. Stock
Summary: This study established an international birth cohort with 2.28 million pregnancies and babies from five countries, aiming to investigate the safety and efficacy of antenatal corticosteroids (ACS). This large-scale cohort enables the assessment of important rare outcomes such as perinatal mortality and provides a comprehensive evaluation of the short- and long-term safety and efficacy of ACS.
Review
Obstetrics & Gynecology
Anna Davies, Sadie Mullin, Sarah Chapman, Katie Barnard, Danya Bakhbakhi, Rachel Ion, Francesca Neuberger, Judith Standing, Abi Merriel, Abigail Fraser, Christy Burden
Summary: Sub-optimal medication adherence in pregnant women with chronic disease and pregnancy-related indications can have negative effects on maternal and perinatal outcomes. This study aimed to identify effective interventions to promote medication adherence in pregnant and planning pregnancy women and assess their impact on perinatal, maternal disease-related, and adherence outcomes.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Cardiac & Cardiovascular Systems
Maria C. Magnus, McKenzie K. Wallace, Jill R. Demirci, Janet M. Catov, Mandy J. Schmella, Abigail Fraser
Summary: This study investigated the long-term effects of breastfeeding duration and exclusivity on cardiometabolic health and whether this relationship differs for women with a history of hypertensive disorders of pregnancy (HDP).
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Psychology, Biological
Clara Calvert, Meredith (Merilee) Brockway, Helga Zoega, Jessica E. Miller, Jasper V. Been, Adeladza Kofi Amegah, Amy Racine-Poon, Solmaz Eradat Oskoui, Ishaya I. Abok, Nima Aghaeepour, Christie D. Akwaowo, Belal N. Alshaikh, Adejumoke I. Ayede, Fabiana Bacchini, Behzad Barekatain, Rodrigo Barnes, Karolina Bebak, Anick Berard, Zulfiqar A. Bhutta, Jeffrey R. Brook, Lenroy R. Bryan, Kim N. Cajachagua-Torres, Marsha Campbell-Yeo, Dinh-Toi Chu, Kristin L. Connor, Luc Cornette, Sandra Cortes, Mandy Daly, Christian Debauche, Iyabode Olabisi F. Dedeke, Kristjana Einarsdottir, Hilde Engjom, Guadalupe Estrada-Gutierrez, Ilaria Fantasia, Nicole M. Fiorentino, Meredith Franklin, Abigail Fraser, Onesmus W. Gachuno, Linda A. Gallo, Mika Gissler, Siri E. Haberg, Abbas Habibelahi, Jonas Haeggstroem, Lauren Hookham, Lisa Hui, Luis Huicho, Karen J. Hunter, Sayeeda Huq, K. C. Ashish, Seilesh Kadambari, Roya Kelishadi, Narjes Khalili, Joanna Kippen, Kirsty Le Doare, Javier Llorca, Laura A. Magee, Maria C. Magnus, Kenneth K. C. Man, Patrick M. Mburugu, Rishi P. Mediratta, Andrew D. Morris, Nazeem Muhajarine, Rachel H. Mulholland, Livia Nagy Bonnard, Victoria Nakibuuka, Natasha Nassar, Sylvester D. Nyadanu, Laura Oakley, Adesina Oladokun, Oladapo O. Olayemi, Olanike A. Olutekunbi, Rosena O. Oluwafemi, Taofik O. Ogunkunle, Chris Orton, Anne K. oertqvist, Joseph Ouma, Oyejoke Oyapero, Kirsten R. Palmer, Lars H. Pedersen, Gavin Pereira, Isabel Pereyra, Roy K. Philip, Dominik Pruski, Marcin Przybylski, Hugo G. Quezada-Pinedo, Annette K. Regan, Natasha R. Rhoda, Tonia A. Rihs, Taylor Riley, Thiago Augusto Hernandes Rocha, Daniel L. Rolnik, Christoph Saner, Francisco J. Schneuer, Vivienne L. Souter, Olof Stephansson, Shengzhi Sun, Emma M. Swift, Miklos Szabo, Marleen Temmerman, Lloyd Tooke, Marcelo L. Urquia, Peter von Dadelszen, Gregory A. Wellenius, Clare Whitehead, Ian C. K. Wong, Rachael Wood, Katarzyna Wroblewska-Seniuk, Kojo Yeboah-Antwi, Christopher S. Yilgwan, Agnieszka Zawiejska, Aziz Sheikh, Natalie Rodriguez, David Burgner, Sarah J. Stock, Meghan B. Azad
Summary: An analysis of 52 million births in 26 countries suggests that there were slight reductions in preterm birth rates during the first to third months of lockdown. However, further research is needed to understand the causal pathways. Preterm birth is a significant cause of infant mortality globally. The study also found variations in stillbirth rates across different countries. The findings highlight the importance of studying the effects of lockdown measures on birth outcomes.
NATURE HUMAN BEHAVIOUR
(2023)
Article
Gastroenterology & Hepatology
Rosalind Tang, Kushala W. M. Abeysekera, Laura D. Howe, Alun D. Hughes, Abigail Fraser
Summary: Non-alcoholic fatty liver disease is associated with cardiovascular health, especially with stroke index and heart rate. Liver fibrosis is associated with several cardiovascular measures, including indicators of subclinical atherosclerosis.
HEPATOLOGY COMMUNICATIONS
(2023)
Review
Medicine, Research & Experimental
Helen Casey, Natalie Dennehy, Abigail Fraser, Christoph Lees, Carmel M. Mceniery, Kayley Scott, Ian B. Wilkinson, Christian Delles
Summary: Gestational hypertension, preeclampsia, and intrauterine growth restriction are associated with increased cardiovascular risk to the mother later in life. The development of placental syndromes and long-term cardiovascular risk is influenced by a woman's pre-conception cardiovascular health. Preclinical studies in models of preeclampsia inform our understanding of the links with later cardiovascular disease, and current pre-pregnancy studies explain the relative contributions of pre-conception factors and the occurrence of placental syndromes to long-term cardiovascular disease.
Article
Peripheral Vascular Disease
Hannah C. M. Taylor, Nishi Chaturvedi, George Davey Smith, Diana L. S. Ferreira, Abigail Fraser, Laura D. Howe, Alun D. Hughes, Debbie A. Lawlor, Nic J. Timpson, Chloe M. Park
Summary: This study investigated the appropriate allometric scaling relationships between left ventricular mass (LVM) and height, total lean mass, and body surface area in healthy adolescents. The results suggest that pooled data without adjustment for sex may introduce bias in allometric scaling estimates. Clinicians should consider body size, body composition, sex, and age when assessing left ventricular mass.
Article
Clinical Neurology
Daisy C. P. Crick, Eleanor Sanderson, Hannah Jones, Neil Goulding, Maria Carolina Borges, Gemma Clayton, Alice R. Carter, Sarah Halligan, Deborah A. Lawlor, Golam M. Khandaker, Abigail Fraser
Summary: This study examined the relationship between inflammation and depression using data from the ALSPAC birth cohort. The findings suggest that while there is no consistent evidence for an effect of inflammation on depression, there is evidence that depression may increase inflammation, which may be confounded by body mass index.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Endocrinology & Metabolism
Judith Nir, Marianna Rachmiel, Abigail Fraser, Yael Lebenthal, Avivit Brener, Orit Pinhas-Hamiel, Alon Haim, Eve Stern, Noa Levek, Tal Ben-Ari, Zohar Landau
Summary: This study aimed to examine the impact of transitioning to an OS-AIDs on glycemic parameters and quality of life in type 1 diabetes patients. The results showed that the use of OS-AIDs improved blood glucose control and quality of life, regardless of age, diabetes duration, or socioeconomic position. This study provides further evidence of the effectiveness of OS-AIDs in the pediatric population.
Article
Psychiatry
C. Prince, C. Joinson, A. S. F. Kwong, A. Fraser, J. Heron
Summary: This study found that early menarche was associated with higher levels of depressive symptoms at age 14 but the association attenuated at 24 years. Late menarche, on the other hand, was associated with lower levels of depressive symptoms at age 14 but this association also attenuated at 24 years.
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2023)
