Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation

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Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel

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Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo

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PET Imaging of Tau Pathology and Relationship to Amyloid, Longitudinal MRI, and Cognitive Change in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI)

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Cryo-EM structures of tau filaments from Alzheimer’s disease

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Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation

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The neurotoxicity of amyloid β-protein oligomers is reversible in a primary neuron model

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Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden

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A Theoretical Analysis of the Synergy of Amyloid and Tau in Alzheimer’s Disease

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A seeding based cellular assay of tauopathy

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The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy

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Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein

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PART, a distinct tauopathy, different from classical sporadic Alzheimer disease

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Aβ “Stretching-and-Packing” Cross-Seeding Mechanism Can Trigger Tau Protein Aggregation

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Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry

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The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

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Proteopathic tau seeding predicts tauopathy in vivo

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Biomarker-based prediction of progression in MCI: comparison of AD signature and hippocampal volume with spinal fluid amyloid-β and tau

(2014) Bradford Dickerson   Frontiers in Aging Neuroscience

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(2014) George S. Bloom   JAMA Neurology

Cell-based Models To Investigate Tau Aggregation

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Biomarker Modeling of Alzheimer’s Disease

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Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

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Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta

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The Toxicity of Amyloid ß Oligomers

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Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

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The Dynamic Structure of Filamentous Tau

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Amyloid and tau proteins in cortical brain biopsy and Alzheimer's disease

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Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY