Review
Microbiology
Arne Schwelm, Jutta Ludwig-Mueller
Summary: The article reviews the current use of genomic information for molecular identification of pathotypes, focusing on effector candidates and pathotype-specific genes, and attempts to connect marker genes to the Plasmodiophora brassicae genome. The potentials, obstacles, and future perspectives for practical applications are discussed.
Article
Plant Sciences
Muhammad Asim Javed, Arne Schwelm, Nazanin Zamani-Noor, Rasha Salih, Marina Silvestre Vano, Jiaxu Wu, Melaine Gonzalez Garcia, Thies Marten Heick, Chaoyu Luo, Priyavashini Prakash, Edel Perez-Lopez
Summary: Plasmodiophora brassicae is a major threat to the rapeseed and brassica vegetable industry, causing clubroot disease in cruciferous plants. The disease is characterized by wilting, stunting, yellowing, and the presence of club-shaped galls in the roots.
MOLECULAR PLANT PATHOLOGY
(2023)
Article
Horticulture
Andrea Botero-Ramirez, Fabian Leonardo Padilla-Huertas, Stephen E. Strelkov, Celsa Garcia-Dominguez
Summary: Clubroot is a major disease of cruciferous crops in Colombia, and its distribution and epidemiology in the country are not well understood. This study found that more than half of the surveyed fields were clubroot-infested, with the highest infestation rate in Norte de Santander. Pathogen inoculum density and average temperature were both positively associated with the likelihood of field infestation.
Article
Agronomy
Wenxing Pang, Xue Zhang, Yinbo Ma, Yingjun Wang, Zongxiang Zhan, Zhongyun Piao
Summary: In this study, the clubroot resistance gene CRA3.7 was fine-mapped and a closely linked marker syau-InDel3008 was developed for marker-assisted selection in Chinese cabbage breeding. Bra019376, Bra019401, Bra019403, and Bra019410 were identified as the most likely candidate genes for CRA3.7. This research provides valuable germplasm resources against Plasmodiophora brassicae Pb3.
THEORETICAL AND APPLIED GENETICS
(2022)
Article
Horticulture
Jiawei Zou, Shiqi Gao, Bo Zhang, Wenjie Ge, Jing Zhang, Ruiqin Ji
Summary: Clubroot disease caused by P. brassicae has significantly affected the production of Brassica rapa crops. The mechanism of interaction between P. brassicae and Brassica rapa is not clear. In this study, a differentially expressed protein, BrCAP, was identified and found to play a potential role in the resistance progress of Chinese cabbage to P. brassicae.
Article
Biochemistry & Molecular Biology
Liyan Kong, Xiaonan Li, Zongxiang Zhan, Zhongyun Piao
Summary: Plasmodiophora brassicae, an intracellular pathogen, has unique sugar transporters that enable it to utilize the host's carbohydrates for survival. These transporters are upregulated during late infection stages when a significant amount of energy is required.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Wei Wang, Li Qin, Wenjing Zhang, Linghui Tang, Chao Zhang, Xiaojing Dong, Pei Miao, Meng Shen, Huilong Du, Hangyuan Cheng, Ke Wang, Xiangyun Zhang, Min Su, Hongwei Lu, Chang Li, Qiang Gao, Xiaojuan Zhang, Yun Huang, Chengzhi Liang, Jian-Min Zhou, Yu-hang Chen
Summary: A broad-spectrum clubroot resistance gene, WeiTsing (WTS), was isolated and characterized from Arabidopsis. WTS is activated upon infection by the clubroot pathogen Plasmodiophora brassicae (Pb) in the pericycle, preventing pathogen colonization in the stele. Brassica napus carrying the WTS gene showed strong resistance to Pb.
Article
Biotechnology & Applied Microbiology
Swati Megha, Zhengping Wang, Nat N. Kav, Habibur Rahman
Summary: In this study, 43 Biotin carboxyl carrier protein (BCCP) genes were identified and analyzed in five Brassica species. The results suggest that these genes may play important roles in stress tolerance in plants. This study provides a foundation for improving stress tolerance in Brassica crops.
Article
Biochemistry & Molecular Biology
Huishan Liu, Chinedu Charles Nwafor, Yinglan Piao, Xiaonan Li, Zongxiang Zhan, Zhongyun Piao
Summary: In this study, circRNA-seq was performed to investigate the role of circRNAs in clubroot disease resistance in Brassica rapa. Differentially expressed circRNAs were identified and a circRNA-miRNA-mRNA network was constructed. One upregulated circRNA was found to suppress the expression of a miRNA and upregulate a gene, possibly leading to plant resistance. These findings provide new insights into clubroot resistance mechanisms and lay the foundation for further studies on complex gene regulation networks in B. rapa.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Qian Li, Nadil Shah, Xueqing Zhou, Huiying Wang, Wenlin Yu, Jiajie Luo, Yajun Liu, Genze Li, Chao Liu, Chunyu Zhang, Peng Chen
Summary: The study revealed that miRNAs play different roles in response to Clubroot disease infection in resistant and susceptible plants, potentially participating in the resistance mechanisms through regulating growth, cell death, and metabolic pathways.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Agronomy
Usha Rani Patar, Marie Manasova, Jonas Hnatek, Jana Wenzlova, Miloslav Zouhar
Summary: The effectiveness of ethanedinitrile (EDN) against Plasmodiophora brassicae, the causative agent of clubroot disease, was evaluated in this study. The results showed that EDN exhibited good efficacy against the pathogen, with complete disease control achieved at certain rates and durations of exposure. Additionally, EDN improved plant health by increasing shoot weight.
Article
Plant Sciences
Wang Chen, Yan Li, Ruibin Yan, Li Ren, Fan Liu, Lingyi Zeng, Shengnan Sun, Huihui Yang, Kunrong Chen, Li Xu, Lijiang Liu, Xiaoping Fang, Shengyi Liu
Summary: Plants have evolved strategies to combat pathogen infection, with SnRK1 playing a role in enhancing resistance. The interaction between PBZF1 and SnRK1.1 was found to inhibit the latter's biological functions, promoting plant susceptibility to clubroot disease. This study provides insights into plant resistance and genetic improvement against clubroot disease caused by the plant-pathogenic protist P. brassicae.
MOLECULAR PLANT PATHOLOGY
(2021)
Review
Plant Sciences
Heather H. Tso, Leonardo Galindo-Gonzalez, Stephen E. Strelkov
Summary: Clubroot, caused by Plasmodiophora brassicae, is a serious threat to cruciferous vegetables worldwide, with current pathotype identification methods being time-consuming and labor-intensive. Research is focusing on genotypic pathotyping to improve sensitivity and specificity in order to enhance early detection and management strategies for the disease.
Article
Plant Sciences
Bo Zhang, Hui Feng, Wenjie Ge, Xinlei Wang, Jing Zhang, Ruiqin Ji
Summary: Chinese cabbage is an important vegetable crop in China, but it has been greatly affected by the clubroot disease caused by the infection of P. brassicae. The BrUFO gene has shown significant up-regulation in diseased roots of Chinese cabbage infected with P. brassicae. It is important to study the function of UFO in response to P. brassicae.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemical Research Methods
Heather H. Tso, Leonardo Galindo-Gonzalez, Troy Locke, Stephen E. Strelkov
Summary: This study describes the development of two rapid and sensitive technologies for pathotyping of Plasmodiophora brassicae. Both assays showed high-throughput potential and accuracy, making them promising as SNP-based pathotype identification tools for clubroot diagnostics.
Article
Biotechnology & Applied Microbiology
Beatriz Alvarez, Kasper Krogh-Andersen, Christian Tellgren-Roth, Noelia Martinez, Goekce Guenaydin, Yin Lin, M. Cruz Martin, Miguel A. Alvarez, Lennart Hammarstroem, Harold Marcotte
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2015)
Article
Virology
Hongxing Zhao, Maoshan Chen, Christian Tellgren-Roth, Ulf Pettersson
Article
Genetics & Heredity
Dongqing Xu, Fang Lin, Yan Jiang, Junjie Ling, Chamari Hettiarachchi, Christian Tellgren-Roth, Magnus Holm, Ning Wei, Xing Wang Deng
Article
Endocrinology & Metabolism
Navya Laxman, Carl-Johan Rubin, Hans Mallmin, Olle Nilsson, Christian Tellgren-Roth, Andreas Kindmark
Letter
Public, Environmental & Occupational Health
G. Starlander, C. Tellgren-Roth, A. Melhus
JOURNAL OF HOSPITAL INFECTION
(2016)
Article
Evolutionary Biology
Ahmed Sayadi, Elina Immonen, Christian Tellgren-Roth, Goran Arnqvist
GENOME BIOLOGY AND EVOLUTION
(2017)
Article
Public, Environmental & Occupational Health
S. Sutterlin, M. Dahlo, C. Tellgren-Roth, W. Schaal, A. Melhus
JOURNAL OF HOSPITAL INFECTION
(2017)
Article
Biochemistry & Molecular Biology
Yafeng Zhu, Par G. Engstrom, Christian Tellgren-Roth, Charles D. Baudo, John C. Kennell, Sheng Sun, R. Blake Billmyre, Markus S. Schroder, Anna Andersson, Tina Holm, Benjamin Sigurgeirsson, Guangxi Wu, Sundar Ram Sankaranarayanan, Rahul Siddharthan, Kaustuv Sanyal, Joakim Lundeberg, Bjorn Nystedt, Teun Boekhout, Thomas L. Dawson, Joseph Heitman, Annika Scheynius, Janne Lehtio
NUCLEIC ACIDS RESEARCH
(2017)
Article
Multidisciplinary Sciences
Torbjorn Olshoj Jensen, Christian Tellgren-Roth, Stephanie Redl, Jerome Maury, Simo Abdessamad Baallal Jacobsen, Lasse Ebdrup Pedersen, Alex Toftgaard Nielsen
NATURE COMMUNICATIONS
(2019)
Article
Ecology
Ahmed Sayadi, Alvaro Martinez Barrio, Elina Immonen, Jacques Dainat, David Berger, Christian Tellgren-Roth, Bjorn Nystedt, Goran Arnqvist
NATURE ECOLOGY & EVOLUTION
(2019)
Article
Biology
Sundar Ram Sankaranarayanan, Giuseppe Ianiri, Marco A. Coelho, Md Hashim Reza, Bhagya C. Thimmappa, Promit Ganguly, Rakesh Netha Vadnala, Sheng Sun, Rahul Siddharthan, Christian Tellgren-Roth, Thomas L. Jnr Dawson, Joseph Heitman, Kaustuv Sanyal
Article
Multidisciplinary Sciences
Orlando Yanez, Julio Chavez-Galarza, Christian Tellgren-Roth, M. Alice Pinto, Peter Neumann, Joachim R. de Miranda
SCIENTIFIC REPORTS
(2020)
Article
Microbiology
Alberto J. Martin-Rodriguez, Shawn M. Higdon, Kaisa Thorell, Christian Tellgren-Roth, Asa Sjoling, Michael Y. Galperin, Tino Krell, Ute Romling
Summary: This study systematically analyzed the c-di-GMP and chemosensory signal transduction pathways in S. algae, revealing its strong signaling capacities and describing six novel sensory domains. These findings contribute to a better understanding of the ecophysiology of S. algae and establish it as a promising model for the analysis of metabolic and signaling pathways within the genus Shewanella.
Article
Microbiology
Antonio D. Moreno, Christian Tellgren-Roth, Lucile Soler, Jacques Dainat, Lisbeth Olsson, Cecilia Geijer
GENOME ANNOUNCEMENTS
(2017)