Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase

Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production

(2019) Elsa Sanchez-Lopez et al.   Cell Metabolism

Identification of a Unique Inhibitor-Binding Site on Choline Kinase α

(2018) Stefanie L. Kall et al.   BIOCHEMISTRY

The Unique Domain Forms a Fuzzy Intramolecular Complex in Src Family Kinases

(2017) Miguel Arbesú et al.   STRUCTURE

Choline kinase alpha—Putting the ChoK-hold on tumor metabolism

(2016) Sean P. Arlauckas et al.   PROGRESS IN LIPID RESEARCH

Structure of the c-Src-SH3 domain in complex with a proline-rich motif of NS5A protein from the hepatitis C virus

(2015) Julio Bacarizo et al.   JOURNAL OF STRUCTURAL BIOLOGY

Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1

(2015) Lucía Serrán-Aguilera et al.   Molecular Informatics

Choline kinase inhibition in rheumatoid arthritis

(2014) M Guma et al.   ANNALS OF THE RHEUMATIC DISEASES

Choline Kinase β Mutant Mice Exhibit Reduced Phosphocholine, Elevated Osteoclast Activity, and Low Bone Mass

(2014) Jasreen Kular et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preclinical Characterization of RSM-932A, a Novel Anticancer Drug Targeting the Human Choline Kinase Alpha, an Enzyme Involved in Increased Lipid Metabolism of Cancer Cells

(2014) J. C. Lacal et al.   MOLECULAR CANCER THERAPEUTICS

Differential Sensitivity of Src-Family Kinases to Activation by SH3 Domain Displacement

(2014) Jamie A. Moroco et al.   PLoS One

Antiplasmodial Activity and Mechanism of Action of RSM-932A, a Promising Synergistic Inhibitor of Plasmodium falciparum Choline Kinase

(2013) Tahl Zimmerman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Kinetic and mechanistic characterisation of Choline Kinase-α

(2013) Catherine S. Hudson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Polyproline-II Helix in Proteins: Structure and Function

(2013) Alexei A. Adzhubei et al.   JOURNAL OF MOLECULAR BIOLOGY

A non-catalytic role of choline kinase alpha is important in promoting cancer cell survival

(2013) S C Falcon et al.   Oncogenesis

Folic acid inhibits endothelial cell proliferation through activating the cSrc/ERK 2/NF-κB/p53 pathway mediated by folic acid receptor

(2012) Shyr-Yi Lin et al.   ANGIOGENESIS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation

(2011) T Miyake et al.   ONCOGENE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Activation of Phosphatidylcholine Cycle Enzymes in Human Epithelial Ovarian Cancer Cells

(2010) E. Iorio et al.   CANCER RESEARCH

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3

(2010) Bum Soo Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding the muscular dystrophy caused by deletion of choline kinase beta in mice

(2009) Gengshu Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K/AKT signaling

(2009) A Yalcin et al.   ONCOGENE

GD3 Synthase Overexpression Sensitizes Hepatocarcinoma Cells to Hypoxia and Reduces Tumor Growth by Suppressing the cSrc/NF-κB Survival Pathway

(2009) Josep M. Lluis et al.   PLoS One

Biochemical characterization of the initial steps of the Kennedy pathway inTrypanosoma brucei: the ethanolamine and choline kinases

(2008) Federica Gibellini et al.   BIOCHEMICAL JOURNAL

Choline Kinase Alpha Depletion Selectively Kills Tumoral Cells

(2008) Monica Banez-Coronel et al.   CURRENT CANCER DRUG TARGETS

The SH3 domain- a family of versatile peptide- and protein-recognition module

(2008) Tomonori Kaneko   Frontiers in Bioscience-Landmark