Targeted genomic CRISPR-Cas9 screen identifies MAP4K4 as essential for glioblastoma invasion
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Title
Targeted genomic CRISPR-Cas9 screen identifies MAP4K4 as essential for glioblastoma invasion
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-30
DOI
10.1038/s41598-019-50160-w
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Note: Only part of the references are listed.- Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells
- (2019) Graham MacLeod et al. Cell Reports
- 2-Aminopyridine-Based Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Inhibitors: Assessment of Mechanism-Based Safety
- (2018) Robert L. Dow et al. JOURNAL OF MEDICINAL CHEMISTRY
- An anatomic transcriptional atlas of human glioblastoma
- (2018) Ralph B. Puchalski et al. SCIENCE
- MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive behavior of medulloblastoma cells
- (2018) Dimitra Tripolitsioti et al. Oncotarget
- Intratumoral heterogeneity of endogenous tumor cell invasive behavior in human glioblastoma
- (2018) Jonathon J. Parker et al. Scientific Reports
- MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance
- (2017) Xuan Gao et al. Molecular Oncology
- Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
- (2017) David W. Morgens et al. Nature Communications
- A Human Glioblastoma Organotypic Slice Culture Model for Study of Tumor Cell Migration and Patient-specific Effects of Anti-Invasive Drugs
- (2017) Jonathon J. Parker et al. Jove-Journal of Visualized Experiments
- Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes
- (2016) David W Morgens et al. NATURE BIOTECHNOLOGY
- Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases
- (2016) Joseph V. Virbasius et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- MAP4K4 promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma
- (2016) Xiao-Jun Feng et al. TUMOR BIOLOGY
- MAP4K4: an emerging therapeutic target in cancer
- (2016) Xuan Gao et al. Cell and Bioscience
- MAP4K4 Is a Threonine Kinase That Phosphorylates FARP1
- (2015) Adam G. Schwaid et al. ACS Chemical Biology
- The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit
- (2015) Lawrence L. LeClaire et al. JOURNAL OF CELL BIOLOGY
- Open source software for quantification of cell migration, protrusions, and fluorescence intensities
- (2015) David J. Barry et al. JOURNAL OF CELL BIOLOGY
- MAP4K4 regulates integrin-FERM binding to control endothelial cell motility
- (2015) Philip Vitorino et al. NATURE
- Identification and characterization of essential genes in the human genome
- (2015) T. Wang et al. SCIENCE
- Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment
- (2015) Mark Ammirati et al. ACS Medicinal Chemistry Letters
- Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
- (2014) Luke A. Gilbert et al. CELL
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- miRNA-141, Downregulated in Pancreatic Cancer, Inhibits Cell Proliferation and Invasion by Directly Targeting MAP4K4
- (2013) Gang Zhao et al. MOLECULAR CANCER THERAPEUTICS
- Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma
- (2013) J. J. Parker et al. NEURO-ONCOLOGY
- Functional Cross Talk between CXCR4 and PDGFR on Glioblastoma Cells Is Essential for Migration
- (2013) Miriam Sciaccaluga et al. PLoS One
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System
- (2013) Tim Wang et al. SCIENCE
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- PDGF and PDGF receptors in glioma
- (2012) Inga Nazarenko et al. UPSALA JOURNAL OF MEDICAL SCIENCES
- Cell Adhesion Molecules: Role and Clinical Significance in Cancer
- (2009) Nektaria Makrilia et al. CANCER INVESTIGATION
- Biomarkers for epithelial-mesenchymal transitions
- (2009) Michael Zeisberg et al. JOURNAL OF CLINICAL INVESTIGATION
- The Role of Myosin II in Glioma Invasion of the Brain
- (2008) Christopher Beadle et al. MOLECULAR BIOLOGY OF THE CELL
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