Article
Nutrition & Dietetics
Changwei Cao, Zhichao Xiao, Huiquan Tong, Yuntao Liu, Yinglong Wu, Changrong Ge
Summary: The study found that orally administered chicken bone collagen peptides have significant effects in alleviating skin aging by improving the composition and structure of aging skin, enhancing skin antioxidant levels, and inhibiting inflammation. The mechanism of action involves reducing skin oxidation, activating the TGF-beta/Smad signaling pathway for collagen synthesis, inhibiting collagen degradation, and suppressing skin inflammation. It was also discovered that lysosomes activation may play an important role in the anti-aging effects of orally administered collagen peptides.
Article
Dermatology
Hend Al-Atif
Summary: Both oral and topical collagen can help reduce or delay skin aging by improving skin moisture, elasticity, hydration, and reducing wrinkles and roughness. There were no side effects reported in the reviewed studies.
DERMATOLOGY PRACTICAL & CONCEPTUAL
(2022)
Article
Dermatology
Melissa Moy, Isabel Diaz, Ewelina Lesniak, Giorgiana Giancola
Summary: This study evaluated the efficacy of a facial serum containing neuropeptides, proteins, amino acids, and marine extracts on aged skin through ex vivo and clinical tests. The results showed that the serum significantly improved skin condition by reducing microfolds and roughness, increasing epidermal thickness, and providing increased moisturization. Dermatological evaluation also demonstrated significant improvements in skin smoothness, wrinkles severity, fine lines visibility, and lifting and tightening effects. Overall, the facial serum showed promising results in improving the quality of aged skin.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Dermatology
Morgann B. Young, Wei Lai, Tatiana Kononov, Alisar S. Zahr
Summary: This study assessed the efficacy and tolerability of a topical anti-aging neck treatment in Chinese women with mild to moderate signs of aging on the neck and jawline. The treatment significantly improved the appearance of wrinkles, elasticity, hydration, gloss/radiance, and skin tone evenness, and was well perceived and tolerated by the subjects.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Pengbo Cui, Mengyu Li, Tianlun Shao, Mingxiao Yu, Weixue Zhao, Yanzhuo Song, Yuting Ding, Jianhua Liu
Summary: The study investigates the calcium-binding capacity of porcine nasal cartilage type II collagen-derived peptides (PNCPs) and characterizes the resulting PNCPs-Ca complex. It finds that PNCPs shows the highest calcium-binding capacity under specific enzymatic hydrolysis conditions, and the complex exhibits a stable beta-sheet structure. These findings provide a scientific basis for developing novel calcium supplements and reducing resource waste.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Cell Biology
Kedar N. Prasad
Summary: Human aging involves gradual decline in organ functions leading to age-related chronic diseases such as Alzheimer's disease (AD). Cellular defects associated with aging and AD include oxidative stress, chronic inflammation, autophagy defects, mitochondrial dysfunction, imbalances in probiotics, telomere attrition, loss of collagen, elastin, and hyaluronic acid, failure of DNA repair system, impaired immune function, increased production of beta-amyloids, hyperphosphorylation of tau protein, and abnormal behaviors. Supplementation with micronutrients, probiotics, collagen peptides, CBD, and modifications in diet and lifestyle may reduce aging processes, and the development, progression of AD, and improve treatments.
MECHANISMS OF AGEING AND DEVELOPMENT
(2023)
Article
Nutrition & Dietetics
Laura Soriano-Romani, Juan Antonio Nieto, Lidia Tomas-Cobos, Elena Diez-Sanchez
Summary: This study aims to evaluate the in vitro osteogenic activity of Phoscollagen (R) peptide-mineral complex. The results show that this complex can stimulate the activity of mature osteoblasts, promoting bone formation.
NUTRICION HOSPITALARIA
(2022)
Article
Biochemistry & Molecular Biology
Christina E. Larder, Michele M. Iskandar, Stan Kubow
Summary: The study found differences in the absorption and metabolism of bioactive peptides in collagen hydrolysates in the human body, further research is needed on the mechanisms and effects related to the liver.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2021)
Article
Cell & Tissue Engineering
Jun Xu, Fangyu Xing, Xi Luo, Jianping Gao, Yang Zhang, Guifeng Zhang, Xinpeng Bai, Ching-Cheng Huang
Summary: The study establishes a method for quantifying bovine collagen type V using high-performance liquid chromatography coupled to mass spectrometry, which was successfully applied to determine the content of Col. V in the bovine heart, lung, and cornea. The method has a broad linear range, high precision, and accuracy, making it suitable for quantifying Col. V in tissue samples.
TISSUE ENGINEERING PART C-METHODS
(2022)
Article
Dermatology
Almudena Martin-Martinez, Noelia Sanchez-Marzo, Diana Martinez-Casanova, Mercedes Abarquero-Cerezo, Maria Herranz-Lopez, Enrique Barrajon-Catalan, Maria Matabuena-Yzaguirre
Summary: This study assessed the in vitro antioxidant potential and protection against oxidative stress of a minimalist formula containing natural vitamin C, rice and lupin bio-peptides, hyaluronic acid, and Vichy volcanic mineralizing water. The results showed that the formula exhibited high antioxidant capacity, protected against oxidative stress damage, and stimulated collagen neosynthesis.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Seiko Koizumi, Yoko Okada, Shiroh Miura, Yuuki Imai, Keiji Igase, Yasumasa Ohyagi, Michiya Igase
Summary: In this study, the effects of collagen peptides (CP) containing high concentrations of prolyl-hydroxyproline and hydroxyprolyl-glycine on advanced glycation end products (AGEs) levels in the skin and subcutaneous blood vessel walls were investigated. A total of 31 individuals aged 47-87 years were randomly assigned to receive either CP or a placebo for 12 weeks. The CP group showed significantly lower AGEs levels and a slightly lower insulin resistance index compared to the placebo group, suggesting that fish-derived CP may be effective in reducing AGEs levels and improving insulin resistance.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
(2023)