The Application of Statins in the Regeneration of Bone Defects. Systematic Review and Meta-Analysis

The effect of statins on periodontal treatment—a systematic review with meta-analyses and meta-regression

(2018) Francisco Wilker Mustafa Gomes Muniz et al.   Clinical Oral Investigations

The ability of topical and systemic statins to increase osteogenesis around dental implants: a systematic review of histomorphometric outcomes in animal studies

(2018) V. Moraschini et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

The sole and combined effect of simvastatin and platelet rich fibrin as a filling material in induced bone defect in tibia of albino rats

(2018) Shereen N Raafat et al.   BONE

Ridge Preservation After Maxillary Third Molar Extraction Using 30% Porosity PLGA/HA/β-TCP Scaffolds With and Without Simvastatin

(2017) Miguel Noronha Oliveira et al.   Implant Dentistry

Localized rosuvastatin via implantable bioerodible sponge and its potential role in augmenting bone healing and regeneration

(2016) Howida Kamal Ibrahim et al.   DRUG DELIVERY

Comparison of the Effect of Platelet-Rich Plasma and Simvastatin on Healing of Critical-Size Calvarial Bone Defects

(2016) Nevra Seyhan et al.   JOURNAL OF CRANIOFACIAL SURGERY

The Effect of Local Rosuvastatin on Mandibular Fracture Healing

(2016) Akif Türer et al.   JOURNAL OF CRANIOFACIAL SURGERY

Controlled release of simvastatin-loaded thermo-sensitive PLGA-PEG-PLGA hydrogel for bone tissue regeneration:in vitroandin vivocharacteristics

(2015) Qi Yan et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effects of local application of simvastatin on bone regeneration in femoral bone defects in rabbit

(2015) Konstantinos Papadimitriou et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

SYRCLE’s risk of bias tool for animal studies

(2014) Carlijn R Hooijmans et al.   BMC Medical Research Methodology

Statins as Bioactive Molecules to Support Bone Regeneration

(2014) Sarah Brittain et al.   CURRENT MEDICINAL CHEMISTRY

Topical Application of Slow-Release Simvastatin as a Bone Substitute in Bone Defects in the Rat Tibia: A Pilot Study

(2014) Heli Rushinek et al.   INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS

Evaluation of bone repair of critical size defects treated with simvastatin-loaded poly(lactic-co-glycolic acid) microspheres in rat calvaria

(2014) Lorraine B Ferreira et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

The pharmacology of statins

(2014) Cesare R. Sirtori   PHARMACOLOGICAL RESEARCH

Novel applications of statins for bone regeneration

(2014) Sarita R. Shah et al.   National Science Review

Calvarial defect healing by recruitment of autogenous osteogenic stem cells using locally applied simvastatin

(2013) Cui Yueyi et al.   BIOMATERIALS

Percutaneous lovastatin accelerates bone healing but is associated with periosseous soft tissue inflammation in a canine tibial osteotomy model

(2013) Jason A. Bleedorn et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Therapeutic effect of local administration of low-dose simvastatin-conjugated gelatin hydrogel for fracture healing

(2012) Tomoaki Fukui et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Local injection of lovastatin in biodegradable polyurethane scaffolds enhances bone regeneration in a critical-sized segmental defect in rat femora

(2012) Toshitaka Yoshii et al.   Journal of Tissue Engineering and Regenerative Medicine

Bone healing of critical-sized nasal defects in rabbits by statins in two different carriers

(2011) Aya Mukozawa et al.   CLINICAL ORAL IMPLANTS RESEARCH

Highly efficient release of lovastatin from poly(lactic-co-glycolic acid) nanoparticles enhances bone repair in rats

(2011) Ming-Hua Ho et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The influence of local administration of simvastatin in calvarial bone healing in rats

(2010) Jimmy Cavalcanti Calixto et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE