A versatile noninvasive method for adsorber quantification in batch and column chromatography based on the ionic capacity

Advances in inline quantification of co-eluting proteins in chromatography: Process-data-based model calibration and application towards real-life separation issues

(2015) Nina Brestrich et al.   BIOTECHNOLOGY AND BIOENGINEERING

A systematic approach to improve data quality in high-throughput batch adsorption experiments

(2015) Gregory Barker et al.   ENGINEERING IN LIFE SCIENCES

High-throughput process development: Chromatography media volume definition

(2015) Tryggve Bergander et al.   ENGINEERING IN LIFE SCIENCES

Calibration-free inverse modeling of ion-exchange chromatography in industrial antibody purification

(2015) Tobias Hahn et al.   ENGINEERING IN LIFE SCIENCES

Simulating and Optimizing Preparative Protein Chromatography with ChromX

(2015) Tobias Hahn et al.   JOURNAL OF CHEMICAL EDUCATION

Robust high-throughput batch screening method in 384-well format with optical in-line resin quantification

(2015) Jörg Kittelmann et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Radial scale-down of packed bed chromatography in a thin cylindrical tube for preparative media

(2015) Seungwoon Lee et al.   PROCESS BIOCHEMISTRY

A tool for selective inline quantification of co-eluting proteins in chromatography using spectral analysis and partial least squares regression

(2014) Nina Brestrich et al.   BIOTECHNOLOGY AND BIOENGINEERING

Modeling and robust pooling design of a preparative cation-exchange chromatography step for purification of monoclonal antibody monomer from aggregates

(2014) Niklas Borg et al.   JOURNAL OF CHROMATOGRAPHY A

Development of an intermediate chromatography step in an insulin purification process. The use of a High Throughput Process Development approach based on selectivity parameters

(2014) Eva Heldin et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Modelling of industrial biopharmaceutical multicomponent chromatography

(2013) Edward J. Close et al.   CHEMICAL ENGINEERING RESEARCH & DESIGN

Model-integrated process development demonstrated on the optimization of a robotic cation exchange step

(2012) A. Osberghaus et al.   CHEMICAL ENGINEERING SCIENCE

Optimizing a chromatographic three component separation: A comparison of mechanistic and empiric modeling approaches

(2012) A. Osberghaus et al.   JOURNAL OF CHROMATOGRAPHY A

Preparation, characterization, and process performance of composite fibrous adsorbents as cation exchangers for high throughput and high capacity bioseparations

(2012) Poondi Rajesh Gavara et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Advancements in High Throughput Biophysical Technologies: Applications for Characterization and Screening during Early Formulation Development of Monoclonal Antibodies

(2012) Hardeep S. Samra et al.   MOLECULAR PHARMACEUTICS

How implementation of Quality by Design and advances in Biochemical Engineering are enabling efficient bioprocess development and manufacture

(2011) Sunil Chhatre et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Antibody capture by mixed-mode chromatography: A comprehensive study from determination of optimal purification conditions to identification of contaminating host cell proteins

(2011) Jerome Pezzini et al.   JOURNAL OF CHROMATOGRAPHY A

High-throughput isotherm determination and thermodynamic modeling of protein adsorption on mixed mode adsorbents

(2010) Beckley K. Nfor et al.   JOURNAL OF CHROMATOGRAPHY A

Recovery and purification process development for monoclonal antibody production

(2010) Hui F. Liu et al.   mAbs

Understanding and Modulating Opalescence and Viscosity in a Monoclonal Antibody Formulation

(2009) Branden A. Salinas et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Rational and systematic protein purification process development: the next generation

(2009) Beckley K. Nfor et al.   TRENDS IN BIOTECHNOLOGY

High-throughput screening of chromatographic separations: I. Method development and column modeling

(2008) Jonathan L. Coffman et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-Throughput Process Development: Determination of Dynamic Binding Capacity Using Microtiter Filter Plates Filled with Chromatography Resin

(2008) T. Bergander et al.   BIOTECHNOLOGY PROGRESS

High Throughput Screening for the Design and Optimization of Chromatographic Processes – Miniaturization, Automation and Parallelization of Breakthrough and Elution Studies

(2008) M. Wiendahl et al.   CHEMICAL ENGINEERING & TECHNOLOGY

High Throughput Screening for the Design and Optimization of Chromatographic Processes: Automated Optimization of Chromatographic Phase Systems

(2008) A. Susanto et al.   CHEMICAL ENGINEERING & TECHNOLOGY

Characterization of ion exchange stationary phases via pH transition profiles

(2008) Nika Lendero et al.   JOURNAL OF CHROMATOGRAPHY A

Ion exchange chromatography of monoclonal antibodies: Effect of resin ligand density on dynamic binding capacity

(2008) Ann Marie Hardin et al.   JOURNAL OF CHROMATOGRAPHY A