Renal clearable nanochelators for iron overload therapy

Targeted Brain Delivery of Rabies Virus Glycoprotein 29-Modified Deferoxamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Mice

(2018) Linhao You et al.   ACS Nano

Nanogel-DFO conjugates as a model to investigate pharmacokinetics, biodistribution, and iron chelation in vivo

(2018) Yan Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

ROS-triggered degradable iron-chelating nanogels: Safely improving iron elimination in vivo

(2018) Zhi Liu et al.   JOURNAL OF CONTROLLED RELEASE

Theranostic nanosystems for targeted cancer therapy

(2018) Homan Kang et al.   Nano Today

Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals

(2017) Anthony S. Grillo et al.   SCIENCE

Renal clearable noble metal nanoparticles: photoluminescence, elimination, and biomedical applications

(2017) Jing Xu et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Nonabsorbable Iron Binding Polymers Prevent Dietary Iron Absorption for the Treatment of Iron Overload

(2017) Jian Qian et al.   ACS Macro Letters

Enzymatically Biodegradable Polyrotaxane–Deferoxamine Conjugates for Iron Chelation

(2016) Zhi Liu et al.   ACS Applied Materials & Interfaces

Renal Clearable Organic Nanocarriers for Bioimaging and Drug Delivery

(2016) Homan Kang et al.   ADVANCED MATERIALS

In vivo efficacy, toxicity and biodistribution of ultra-long circulating desferrioxamine based polymeric iron chelator

(2016) Jasmine L. Hamilton et al.   BIOMATERIALS

Iron distribution and histopathological study of the effects of deferoxamine and deferiprone in the kidneys of iron overloaded β-thalassemic mice

(2016) Paranee Yatmark et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Loss of divalent metal transporter 1 function promotes brain copper accumulation and increases impulsivity

(2016) Murui Han et al.   JOURNAL OF NEUROCHEMISTRY

Iron Binding and Iron Removal Efficiency of Desferrioxamine Based Polymeric Iron Chelators: Influence of Molecular Size and Chelator Density

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Pharmacokinetics, pharmacodynamics and toxicology of theranostic nanoparticles

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The Antimicrobial Mechanism of Action of Epsilon-Poly-l-Lysine

(2014) Morten Hyldgaard et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Renal hemosiderosis and rapidly progressive glomerulonephritis associated with primary hemochromatosis

(2014) Sultan Ozkurt et al.   RENAL FAILURE

Central C–C bonding increases optical and chemical stability of NIR fluorophores

(2014) Hoon Hyun et al.   RSC Advances

Design of Long Circulating Nontoxic Dendritic Polymers for the Removal of Iron in Vivo

(2013) Muhammad Imran ul-haq et al.   ACS Nano

His86 from the N-Terminus of Frataxin Coordinates Iron and Is Required for Fe–S Cluster Synthesis

(2013) Leslie E. Gentry et al.   BIOCHEMISTRY

Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia

(2012) Jonghan Kim et al.   FASEB JOURNAL

Synthesis and In Vivo Fate of Zwitterionic Near-Infrared Fluorophores

(2011) Hak Soo Choi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

HFE Gene Variants Affect Iron in the Brain

(2011) Wint Nandar et al.   JOURNAL OF NUTRITION

Iron-Chelating Therapy for Transfusional Iron Overload

(2011) Gary M. Brittenham   NEW ENGLAND JOURNAL OF MEDICINE

Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment

(2010) Antonello Pietrangelo   GASTROENTEROLOGY

Iron-Overload Cardiomyopathy: Pathophysiology, Diagnosis, and Treatment

(2010) Colm J. Murphy et al.   JOURNAL OF CARDIAC FAILURE

Hereditary hemochromatosis: patient experiences of the disease and phlebotomy treatment

(2010) Pierre Brissot et al.   TRANSFUSION

Efficacy and safety of deferasirox, an oral iron chelator, in heavily iron-overloaded patients with β-thalassaemia: the ESCALATOR study

(2009) Ali Taher et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Design considerations for tumour-targeted nanoparticles

(2009) Hak Soo Choi et al.   Nature Nanotechnology

Biomarkers of Acute Kidney Injury

(2008) Charles L. Edelstein   ADVANCES IN CHRONIC KIDNEY DISEASE

Long-term experience with deferasirox (ICL670), a once-daily oral iron chelator, in the treatment of transfusional iron overload

(2008) MD Cappellini et al.   EXPERT OPINION ON PHARMACOTHERAPY