High concentration biotherapeutic formulation and ultrafiltration: Part 1 pressure limits

Buffer-free therapeutic antibody preparations provide a viable alternative to conventionally buffered solutions: From protein buffer capacity prediction to bioprocess applications

(2015) Sven Bahrenburg et al.   Biotechnology Journal

Intrinsic fluorescence-basedat situsoft sensor for monitoring monoclonal antibody aggregation

(2015) Kaveh Ohadi et al.   BIOTECHNOLOGY PROGRESS

Intermolecular Interactions and the Viscosity of Highly Concentrated Monoclonal Antibody Solutions

(2015) Elaheh Binabaji et al.   PHARMACEUTICAL RESEARCH

Buffer-free therapeutic antibody preparations provide a viable alternative to conventionally buffered solutions: From protein buffer capacity prediction to bioprocess applications

(2015) Sven Bahrenburg et al.   Biotechnology Journal

Entanglement Model of Antibody Viscosity

(2014) Jeremy D. Schmit et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Do Clustering Monoclonal Antibody Solutions Really Have a Concentration Dependence of Viscosity?

(2013) Jai A. Pathak et al.   BIOPHYSICAL JOURNAL

Effect of cell culture medium components on color of formulated monoclonal antibody drug substance

(2013) Natarajan Vijayasankaran et al.   BIOTECHNOLOGY PROGRESS

Biopharmaceutical formulations for pre-filled delivery devices

(2013) Jan Jezek et al.   Expert Opinion on Drug Delivery

The Role of Amino Acid Sequence in the Self-Association of Therapeutic Monoclonal Antibodies: Insights from Coarse-Grained Modeling

(2013) Anuj Chaudhri et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Both protein adsorption and aggregation contribute to shear yielding and viscosity increase in protein solutions

(2013) Maria Monica Castellanos et al.   Soft Matter

Weak Interactions Govern the Viscosity of Concentrated Antibody Solutions: High-Throughput Analysis Using the Diffusion Interaction Parameter

(2012) Brian D. Connolly et al.   BIOPHYSICAL JOURNAL

Coarse-Grained Modeling of the Self-Association of Therapeutic Monoclonal Antibodies

(2012) Anuj Chaudhri et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The Influence of Charge Distribution on Self-Association and Viscosity Behavior of Monoclonal Antibody Solutions

(2012) Sandeep Yadav et al.   MOLECULAR PHARMACEUTICS

Structure-Activity Relationship for Hydrophobic Salts as Viscosity-Lowering Excipients for Concentrated Solutions of Monoclonal Antibodies

(2012) Zheng Guo et al.   PHARMACEUTICAL RESEARCH

Behavior of Monoclonal Antibodies: Relation Between the Second Virial Coefficient (B 2) at Low Concentrations and Aggregation Propensity and Viscosity at High Concentrations

(2011) Shuntaro Saito et al.   PHARMACEUTICAL RESEARCH

Hydrophobic salts markedly diminish viscosity of concentrated protein solutions

(2010) Wei Du et al.   BIOTECHNOLOGY AND BIOENGINEERING

Rheological and syringeability properties of highly concentrated human polyclonal immunoglobulin solutions

(2010) V. Burckbuchler et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Understanding and Modulating Opalescence and Viscosity in a Monoclonal Antibody Formulation

(2009) Branden A. Salinas et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Polysorbate 20 prevents the precipitation of a monoclonal antibody during shear

(2009) Thomas W. Patapoff et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Long- and Short-Range Electrostatic Interactions Affect the Rheology of Highly Concentrated Antibody Solutions

(2009) Ravi Chari et al.   PHARMACEUTICAL RESEARCH

Reversible Self-Association of a Concentrated Monoclonal Antibody Solution Mediated by Fab–Fab Interaction That Impacts Solution Viscosity

(2008) Sonoko Kanai et al.   JOURNAL OF PHARMACEUTICAL SCIENCES