Immunological Effects and Viral Gene Expression Determine the Efficacy of Oncolytic Measles Vaccines Encoding IL-12 or IL-15 Agonists

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

(2019) Johannes P.W. Heidbuechel et al.   Jove-Journal of Visualized Experiments

Optimizing oncolytic virotherapy in cancer treatment

(2019) Kevin Harrington et al.   NATURE REVIEWS DRUG DISCOVERY

Newcastle disease virus co-expressing interleukin 7 and interleukin 15 modified tumor cells as a vaccine for cancer immunotherapy

(2018) Xiaojing Xu et al.   CANCER SCIENCE

Targeted BiTE Expression by an Oncolytic Vector Augments Therapeutic Efficacy Against Solid Tumors

(2018) Tobias Speck et al.   CLINICAL CANCER RESEARCH

Superagonist IL-15-armed Oncolytic Virus Elicits Potent Antitumor Immunity and Therapy That Are Enhanced with PD-1 Blockade

(2018) Stacy J. Kowalsky et al.   MOLECULAR THERAPY

Enhanced Control of Oncolytic Measles Virus Using MicroRNA Target Sites

(2018) Mathias Felix Leber et al.   Molecular Therapy-Oncolytics

Potential and clinical translation of oncolytic measles viruses

(2017) Steven Robinson et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The potential and promise of IL-15 in immuno-oncogenic therapies

(2017) Tanya O. Robinson et al.   IMMUNOLOGY LETTERS

Rescue of nonlytic Newcastle Disease Virus (NDV) expressing IL-15 for cancer immunotherapy

(2017) Xiaojing Xu et al.   VIRUS RESEARCH

Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation

(2017) Rūta Veinalde et al.   OncoImmunology

Measles to the Rescue: A Review of Oncolytic Measles Virus

(2016) Sarah Aref et al.   Viruses-Basel

Oncolytic Activity of a Recombinant Measles Virus, Blind to Signaling Lymphocyte Activation Molecule, Against Colorectal Cancer Cells

(2016) Yosuke Amagai et al.   Scientific Reports

Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery

(2016) Suzanne I.S. Mosely et al.   Cancer Immunology Research

First oncolytic virus approved for melanoma immunotherapy

(2015) Jonathan Pol et al.   OncoImmunology

The IL-2 cytokine family in cancer immunotherapy

(2014) Geok Choo Sim et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Preassociation of IL-15 with IL-15R -IgG1-Fc Enhances Its Activity on Proliferation of NK and CD8+/CD44high T Cells and Its Antitumor Action

(2014) S. Dubois et al.   JOURNAL OF IMMUNOLOGY

CTLA-4 and PD-L1 Checkpoint Blockade Enhances Oncolytic Measles Virus Therapy

(2014) Christine E Engeland et al.   MOLECULAR THERAPY

Myxoma Virus Expressing a Fusion Protein of Interleukin-15 (IL15) and IL15 Receptor Alpha Has Enhanced Antitumor Activity

(2014) Vesna Tosic et al.   PLoS One

Granulocyte-Macrophage Colony-Stimulating Factor-Armed Oncolytic Measles Virus Is an Effective Therapeutic Cancer Vaccine

(2013) Christian Grossardt et al.   HUMAN GENE THERAPY

Natural Oncolytic Activity of Live-Attenuated Measles Virus against Human Lung and Colorectal Adenocarcinomas

(2013) Nicolas Boisgerault et al.   Biomed Research International

Interleukin 15 Provides Relief to CTLs from Regulatory T Cell-Mediated Inhibition: Implications for Adoptive T Cell-Based Therapies for Lymphoma

(2012) S. K. Perna et al.   CLINICAL CANCER RESEARCH

Expression of Immunomodulatory Neutrophil-activating Protein of Helicobacter pylori Enhances the Antitumor Activity of Oncolytic Measles Virus

(2012) Ianko D Iankov et al.   MOLECULAR THERAPY

Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity

(2011) K B Stephenson et al.   CANCER GENE THERAPY

Genetic Characterization of Measles Vaccine Strains

(2011) B. Bankamp et al.   JOURNAL OF INFECTIOUS DISEASES

Interleukin-15 biology and its therapeutic implications in cancer

(2011) Jason C. Steel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Oncolytic measles viruses encoding interferon β and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy

(2010) H Li et al.   CANCER GENE THERAPY

Interleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancer

(2009) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measles Virus as An Oncolytic Vector Platform

(2008) Boris Blechacz et al.   CURRENT GENE THERAPY