Carboxypeptidase D is the only enzyme responsible for antibody C-terminal lysine cleavage in Chinese hamster ovary (CHO) cells

Highly efficient targeted chromosome deletions using CRISPR/Cas9

(2014) Zuyong He et al.   BIOTECHNOLOGY AND BIOENGINEERING

Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell

(2013) Zhilan Hu et al.   BIOTECHNOLOGY PROGRESS

Characterization of monoclonal antibody size variants containing extra light chains

(2013) Connie Lu et al.   mAbs

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

RNA-programmed genome editing in human cells

(2013) Martin Jinek et al.   eLife

Probing of C-terminal lysine variation in a recombinant monoclonal antibody production using Chinese hamster ovary cells with chemically defined media

(2012) Jun Luo et al.   BIOTECHNOLOGY AND BIOENGINEERING

C-terminal lysine processing of human immunoglobulin G2 heavy chain in vivo

(2010) Bing Cai et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

siRNA vs. shRNA: Similarities and differences

(2009) Donald D. Rao et al.   ADVANCED DRUG DELIVERY REVIEWS

C-terminal lysine variants in fully human monoclonal antibodies: Investigation of test methods and possible causes

(2008) Lawrence W. Dick et al.   BIOTECHNOLOGY AND BIOENGINEERING

Heterogeneity of Monoclonal Antibodies

(2007) Hongcheng Liu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES