Intestinal M cells: Tireless samplers of enteric microbiota

Intestinal non-canonical NFκB signaling shapes the local and systemic immune response

(2019) Sadeesh K. Ramakrishnan et al.   Nature Communications

Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice

(2019) Shunsuke Kimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activated Peyer′s patch B cells sample antigen directly from M cells in the subepithelial dome

(2019) Rathan Joy Komban et al.   Nature Communications

Airway M Cells Arise in the Lower Airway Due to RANKL Signaling and Reside in the Bronchiolar Epithelium Associated With iBALT in Murine Models of Respiratory Disease

(2019) Shunsuke Kimura et al.   Frontiers in Immunology

IgA Responses to Microbiota

(2018) Jeffrey J. Bunker et al.   IMMUNITY

NALT M cells are important for immune induction for the common mucosal immune system

(2017) Yasuhiro Date et al.   INTERNATIONAL IMMUNOLOGY

Uromodulin–SlpA binding dictates Lactobacillus acidophilus uptake by intestinal epithelial M cells

(2017) Sae Yanagihara et al.   INTERNATIONAL IMMUNOLOGY

Allograft inflammatory factor 1 is a regulator of transcytosis in M cells

(2017) Sari Kishikawa et al.   Nature Communications

TNF-α augments RANKL-dependent intestinal M cell differentiation in enteroid cultures

(2016) Megan B. Wood et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

RANKL regulates differentiation of microfold cells in mouse nasopharynx-associated lymphoid tissue (NALT)

(2015) Mami Mutoh et al.   CELL AND TISSUE RESEARCH

Intestinal M cells

(2015) Hiroshi Ohno   JOURNAL OF BIOCHEMISTRY

Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria

(2015) D Rios et al.   Mucosal Immunology

Mutations in the Borrelia burgdorferi Flagellar Type III Secretion System Genes fliH and fliI Profoundly Affect Spirochete Flagellar Assembly, Morphology, Motility, Structure, and Cell Division

(2015) Tao Lin et al.   mBio

Comprehensive Gene Expression Profiling of Peyer's Patch M Cells, Villous M-Like Cells, and Intestinal Epithelial Cells

(2014) K. Terahara et al.   JOURNAL OF IMMUNOLOGY

Visualization of the entire differentiation process of murine M cells: suppression of their maturation in cecal patches

(2014) S Kimura et al.   Mucosal Immunology

Take five — Type VII secretion systems of Mycobacteria

(2013) Edith N.G. Houben et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The SRC Family Tyrosine Kinase HCK and the ETS Family Transcription Factors SPIB and EHF Regulate Transcytosis across a Human Follicle-associated Epithelium Model

(2013) Tsuneaki Asai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

(2013) N A Mabbott et al.   Mucosal Immunology

Uromodulin: old friend with new roles in health and disease

(2013) Franca M. Iorember et al.   PEDIATRIC NEPHROLOGY

Spi-B is critical for plasmacytoid dendritic cell function and development

(2012) I. Sasaki et al.   BLOOD

M Cell Differentiation: Distinct Lineage or Phenotypic Transition? Salmonella Provides Answers

(2012) Hiroshi Ohno et al.   Cell Host & Microbe

Salmonella Transforms Follicle-Associated Epithelial Cells into M Cells to Promote Intestinal Invasion

(2012) Amin Tahoun et al.   Cell Host & Microbe

Identification of Novel Genes Selectively Expressed in the Follicle-Associated Epithelium from the Meta-Analysis of Transcriptomics Data from Multiple Mouse Cell and Tissue Populations

(2012) A. Kobayashi et al.   DNA RESEARCH

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

Differential intestinal M-cell gene expression response to gut commensals

(2012) Susan Lapthorne et al.   IMMUNOLOGY

Autoantibodies against exocrine pancreas in Crohn's disease are directed against two antigens: The glycoproteins CUZD1 and GP2

(2012) Lars Komorowski et al.   Journal of Crohns & Colitis

Cutting Edge: Brucella abortus Exploits a Cellular Prion Protein on Intestinal M Cells as an Invasive Receptor

(2012) G. Nakato et al.   JOURNAL OF IMMUNOLOGY

Peyer's Patch M Cells Derived from Lgr5+ Stem Cells Require SpiB and Are Induced by RankL in Cultured "Miniguts"

(2012) W. de Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcription factor Spi-B–dependent and –independent pathways for the development of Peyer’s patch M cells

(2012) S Sato et al.   Mucosal Immunology

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

(2012) Jeremiah R. McDole et al.   NATURE

The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells

(2012) Takashi Kanaya et al.   NATURE IMMUNOLOGY

Membrane Fusion Proteins of Type I Secretion System and Tripartite Efflux Pumps Share a Binding Motif for TolC in Gram-Negative Bacteria

(2012) Minho Lee et al.   PLoS One

A Rab32-Dependent Pathway Contributes to Salmonella Typhi Host Restriction

(2012) S. Spano et al.   SCIENCE

Antigen sampling in the small intestine

(2012) Olga Schulz et al.   TRENDS IN IMMUNOLOGY

Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors

(2011) Peter C. Hollenhorst et al.   Annual Review of Biochemistry

CCR6hiCD11cint B cells promote M-cell differentiation in Peyer's patch

(2011) Masashi Ebisawa et al.   INTERNATIONAL IMMUNOLOGY

The Airway Antigen Sampling System: Respiratory M Cells as an Alternative Gateway for Inhaled Antigens

(2011) Dong-Young Kim et al.   JOURNAL OF IMMUNOLOGY

Peptidoglycan recognition proteins kill bacteria by activating protein-sensing two-component systems

(2011) Des Raj Kashyap et al.   NATURE MEDICINE

Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair

(2011) Anthony Bouter et al.   Nature Communications

A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor

(2010) Tao Su et al.   NATURE CELL BIOLOGY

The pancreatic zymogen granule membrane protein, GP2, binds Escherichia colitype 1 Fimbriae

(2009) Su Yu et al.   BMC GASTROENTEROLOGY

New Approach for M-Cell-Specific Molecules Screening by Comprehensive Transcriptome Analysis

(2009) G. Nakato et al.   DNA RESEARCH

Identification of GP2, the major zymogen granule membrane glycoprotein, as the autoantigen of pancreatic antibodies in Crohn's disease

(2009) D. Roggenbuck et al.   GUT

RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium

(2009) K. A. Knoop et al.   JOURNAL OF IMMUNOLOGY

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

(2009) Koji Hase et al.   NATURE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

(2009) Koji Hase et al.   NATURE CELL BIOLOGY

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY