Early Effects of Cyclophosphamide, Methotrexate, and 5-Fluorouracil on Neuronal Morphology and Hippocampal-Dependent Behavior in a Murine Model

Effects of Cyclophosphamide and/or Doxorubicin in a Murine Model of Postchemotherapy Cognitive Impairment

(2017) Timothy J Flanigan et al.   TOXICOLOGICAL SCIENCES

Breast Cancer

(2017) Robert W. Carlson et al.   Journal of the National Comprehensive Cancer Network

Low dose cyclophosphamide: Mechanisms of T cell modulation

(2016) Mutsa Tatenda Madondo et al.   CANCER TREATMENT REVIEWS

The immune system in traumatic brain injury

(2016) Nikolaus Plesnila   CURRENT OPINION IN PHARMACOLOGY

Association of proinflammatory cytokines and chemotherapy-associated cognitive impairment in breast cancer patients: a multi-centered, prospective, cohort study†

(2015) Y. T. Cheung et al.   ANNALS OF ONCOLOGY

Stem Cell Transplantation Reverses Chemotherapy-Induced Cognitive Dysfunction

(2015) M. M. Acharya et al.   CANCER RESEARCH

5-Fluorouracil derivatives: a patent review (2012 – 2014)

(2015) Esmeralda Carrillo et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Chemotherapy, cognitive impairment and hippocampal toxicity

(2015) J. Dietrich et al.   NEUROSCIENCE

Low-doses of cisplatin injure hippocampal synapses: A mechanism for ‘chemo’ brain?

(2014) Adrienne L. Andres et al.   EXPERIMENTAL NEUROLOGY

Central nervous system toxicities of chemotherapeutic agents

(2014) Parvin F Peddi et al.   Expert Review of Anticancer Therapy

The Marginal Division of the Striatum and Hippocampus Has Different Role and Mechanism in Learning and Memory

(2014) Si-Yun Shu et al.   MOLECULAR NEUROBIOLOGY

Modulation of learning and memory by cytokines: Signaling mechanisms and long term consequences

(2014) Elissa J. Donzis et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Reduced Synaptic STIM2 Expression and Impaired Store-Operated Calcium Entry Cause Destabilization of Mature Spines in Mutant Presenilin Mice

(2014) Suya Sun et al.   NEURON

Delayed Administration of Alpha-Difluoromethylornithine Prevents Hippocampus-Dependent Cognitive Impairment after Single and Combined Injury in Mice

(2014) Antiño R. Allen et al.   RADIATION RESEARCH

Neuropsychological care and rehabilitation of cancer patients with chemobrain: strategies for evaluation and intervention development

(2014) Pascal Jean-Pierre et al.   SUPPORTIVE CARE IN CANCER

Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders

(2013) Kwok-On Lai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dysregulation in myelination mediated by persistent neuroinflammation: Possible mechanisms in chemotherapy-related cognitive impairment

(2013) Teresita L. Briones et al.   BRAIN BEHAVIOR AND IMMUNITY

Breast cancer statistics, 2013

(2013) Carol DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Renoprotective effects of montelukast, a cysteinyl leukotriene receptor antagonist, against methotrexate-induced kidney damage in rats

(2013) Ihab T. Abdel-Raheem et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Cytokines as Mediators of Chemotherapy-Associated Cognitive Changes: Current Evidence, Limitations and Directions for Future Research

(2013) Yin Ting Cheung et al.   PLoS One

Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors

(2012) Shelli Kesler et al.   BRAIN BEHAVIOR AND IMMUNITY

The effect of 5-fluorouracil on the long term survival and proliferation of cells in the rat hippocampus

(2012) Maha ELBeltagy et al.   BRAIN RESEARCH BULLETIN

The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study

(2012) G. Winocur et al.   CLINICAL CANCER RESEARCH

Chemotherapy-Related Cognitive Dysfunction

(2012) Jeffrey S. Wefel et al.   Current Neurology and Neuroscience Reports

Neuropsychological Performance in Survivors of Breast Cancer More Than 20 Years After Adjuvant Chemotherapy

(2012) Vincent Koppelmans et al.   JOURNAL OF CLINICAL ONCOLOGY

Stress, anxiety, and dendritic spines: What are the connections?

(2012) B. Leuner et al.   NEUROSCIENCE

Inflammation after trauma: Microglial activation and traumatic brain injury

(2011) Anil F. Ramlackhansingh et al.   ANNALS OF NEUROLOGY

Preserved learning and memory in mice following chemotherapy: 5-Fluorouracil and doxorubicin single agent treatment, doxorubicin–cyclophosphamide combination treatment

(2011) Thane Fremouw et al.   BEHAVIOURAL BRAIN RESEARCH

Chemotherapy-induced cognitive impairment is associated with decreases in cell proliferation and histone modifications

(2011) Teresita L Briones et al.   BMC NEUROSCIENCE

Enhancement of basolateral amygdaloid neuronal dendritic arborization following Bacopa monniera extract treatment in adult rats

(2011) Venkata Ramana Vollala et al.   Clinics

Preserved learning and memory following 5-fluorouracil and cyclophosphamide treatment in rats

(2011) Jeffrey M. Long et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Effects of Cyclophosphamide on Hippocampal Cell Proliferation and Spatial Working Memory in Rat

(2011) Laura Lyons et al.   PLoS One

Cognitive impairments caused by oxaliplatin and 5-fluorouracil chemotherapy are ameliorated by physical activity

(2011) Joanna E. Fardell et al.   PSYCHOPHARMACOLOGY

Differential expression of cytokines in breast cancer patients receiving different chemotherapies: implications for cognitive impairment research

(2011) Michelle C. Janelsins et al.   SUPPORTIVE CARE IN CANCER

Serum levels of NF-κB and pro-inflammatory cytokines following administration of mucotoxic drugs

(2010) Richard M Logan et al.   CANCER BIOLOGY & THERAPY

High-dose cyclophosphamide for graft-versus-host disease prevention

(2010) Leo Luznik et al.   CURRENT OPINION IN HEMATOLOGY

Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons

(2010) A.M. Magariños et al.   HIPPOCAMPUS

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

Calcineurin inhibition with systemic FK506 treatment increases dendritic branching and dendritic spine density in healthy adult mouse brain

(2010) Tara L. Spires-Jones et al.   NEUROSCIENCE LETTERS

Methotrexate reduces hippocampal blood vessel density and activates microglia in rats but does not elevate central cytokine release

(2009) Riejanne Seigers et al.   BEHAVIOURAL BRAIN RESEARCH

IGF-1 Partially Restores Chemotherapy-Induced Reductions in Neural Cell Proliferation in Adult C57BL/6 Mice

(2009) Michelle C. Janelsins et al.   CANCER INVESTIGATION

Cyclophosphamide and cancer: golden anniversary

(2009) Ashkan Emadi et al.   Nature Reviews Clinical Oncology

Sustained expression of interleukin-1β in mouse hippocampus impairs spatial memory

(2009) A.H. Moore et al.   NEUROSCIENCE

Review: Cyclophosphamide in multiple sclerosis: scientific rationale, history and novel treatment paradigms

(2009) Amer Awad et al.   Therapeutic Advances in Neurological Disorders

Balancing Structure and Function at Hippocampal Dendritic Spines

(2008) Jennifer N Bourne et al.   Annual Review of Neuroscience

Chemobrain: A translational challenge for neurotoxicology

(2008) Bernard Weiss   NEUROTOXICOLOGY

Long-lasting suppression of hippocampal cell proliferation and impaired cognitive performance by methotrexate in the rat

(2007) R SEIGERS et al.   BEHAVIOURAL BRAIN RESEARCH