The neuroscience of unmet social needs

Neural mechanisms of social homeostasis

(2019) Gillian A. Matthews et al.   Annals of the New York Academy of Sciences

Loneliness in monkeys: neuroimmune mechanisms

(2019) John P Capitanio et al.   Current Opinion in Behavioral Sciences

To free, or not to free: Social reinforcement effects in the social release paradigm with rats

(2018) Lisa C. Hiura et al.   BEHAVIOURAL PROCESSES

Neurobiology and consequences of social isolation stress in animal model—A comprehensive review

(2018) Faiza Mumtaz et al.   BIOMEDICINE & PHARMACOTHERAPY

New perspectives on central amygdala function

(2018) Jonathan P Fadok et al.   CURRENT OPINION IN NEUROBIOLOGY

The effects of early life stress on reward processing

(2018) Andrew M. Novick et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Home alone: a systematic review and meta-analysis on the effects of individual housing on body weight, food intake and visceral fat mass in rodents

(2018) L. Schipper et al.   Obesity Reviews

Social reinforcement as alternative to sucrose reinforcement is increased by nicotine and methylphenidate in male Fischer-344 rats

(2018) Connor D. Martin et al.   PSYCHOPHARMACOLOGY

An fMRI study of loneliness in younger and older adults

(2018) Alexandra E. D’Agostino et al.   Social Neuroscience

Loneliness predicts a preference for larger interpersonal distance within intimate space

(2018) Elliot A. Layden et al.   PLoS One

Volitional social interaction prevents drug addiction in rat models

(2018) Marco Venniro et al.   NATURE NEUROSCIENCE

Homeostatic circuits selectively gate food cue responses in insular cortex

(2017) Yoav Livneh et al.   NATURE

Neural circuits underlying thirst and fluid homeostasis

(2017) Christopher A. Zimmerman et al.   NATURE REVIEWS NEUROSCIENCE

Brain networks of social action-outcome contingency: The role of the ventral striatum in integrating signals from the sensory cortex and medial prefrontal cortex

(2017) Motofumi Sumiya et al.   NEUROSCIENCE RESEARCH

Gating of social reward by oxytocin in the ventral tegmental area

(2017) Lin W. Hung et al.   SCIENCE

Persistent social isolation reflects identity and social context but not maternal effects or early environment

(2017) L. J. N. Brent et al.   Scientific Reports

Cooperation in rats playing the iterated Prisoner's Dilemma game

(2016) Ruth I. Wood et al.   ANIMAL BEHAVIOUR

The Human Model: Changing Focus on Autism Research

(2016) Alysson Renato Muotri   BIOLOGICAL PSYCHIATRY

Oxidative and nitrosative stress pathways in the brain of socially isolated adult male rats demonstrating depressive- and anxiety-like symptoms

(2016) Dragana Filipović et al.   Brain Structure & Function

Oxytocin-Induced Changes in Monoamine Level in Symmetric Brain Structures of Isolated Aggressive C57Bl/6 Mice

(2016) I. V. Karpova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Dorsal Raphe Dopamine Neurons Represent the Experience of Social Isolation

(2016) Gillian A. Matthews et al.   CELL

No Evidence for Audience Effects in Reciprocal Cooperation of Norway Rats

(2016) Manon K. Schweinfurth et al.   ETHOLOGY

Time to connect: bringing social context into addiction neuroscience

(2016) Markus Heilig et al.   NATURE REVIEWS NEUROSCIENCE

Inhibitory Input from the Lateral Hypothalamus to the Ventral Tegmental Area Disinhibits Dopamine Neurons and Promotes Behavioral Activation

(2016) Edward H. Nieh et al.   NEURON

Mu Opioid Receptor Modulation of Dopamine Neurons in the Periaqueductal Gray/Dorsal Raphe: A Role in Regulation of Pain

(2016) Chia Li et al.   NEUROPSYCHOPHARMACOLOGY

Exploring the relationship between social attachment and dopamine D2/3 receptor availability in the brains of healthy humans using [11C]-(+)-PHNO

(2016) Fernando Caravaggio et al.   Social Neuroscience

Social Isolation Blunted the Response of Mesocortical Dopaminergic Neurons to Chronic Ethanol Voluntary Intake

(2016) Valeria Lallai et al.   Frontiers in Cellular Neuroscience

Effects of craving behavioral intervention on neural substrates of cue-induced craving in Internet gaming disorder

(2016) Jin-Tao Zhang et al.   NeuroImage-Clinical

Rats demonstrate helping behavior toward a soaked conspecific

(2015) Nobuya Sato et al.   ANIMAL COGNITION

Social visual contact, a primary “drive” for social animals?

(2015) Audrey Perret et al.   ANIMAL COGNITION

Chronic social isolation affects thigmotaxis and whole-brain serotonin levels in adult zebrafish

(2015) Soaleha Shams et al.   BEHAVIOURAL BRAIN RESEARCH

Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits

(2015) Yiming Chen et al.   CELL

Decoding Neural Circuits that Control Compulsive Sucrose Seeking

(2015) Edward H. Nieh et al.   CELL

Neural correlates of observing joint actions with shared intentions

(2015) Terry Eskenazi et al.   CORTEX

Cooperation among Norway Rats: The Importance of Visual Cues for Reciprocal Cooperation, and the Role of Coercion

(2015) Vassilissa Dolivo et al.   ETHOLOGY

Thirst driving and suppressing signals encoded by distinct neural populations in the brain

(2015) Yuki Oka et al.   NATURE

Toward Understanding How Early-Life Stress Reprograms Cognitive and Emotional Brain Networks

(2015) Yuncai Chen et al.   NEUROPSYCHOPHARMACOLOGY

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

(2015) J L Silverman et al.   NEUROPSYCHOPHARMACOLOGY

Behavioral and endocrine evaluation of the stressfulness of single-pen housing compared to group-housing and social isolation conditions

(2015) Vanessa Guesdon et al.   PHYSIOLOGY & BEHAVIOR

Myeloid differentiation architecture of leukocyte transcriptome dynamics in perceived social isolation

(2015) Steven W. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Yearning for connection? Loneliness is associated with increased ventral striatum activity to close others

(2015) Tristen K. Inagaki et al.   Social Cognitive and Affective Neuroscience

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

Why we interact: On the functional role of the striatum in the subjective experience of social interaction

(2014) Ulrich J. Pfeiffer et al.   NEUROIMAGE

A Behavioral Taxonomy of Loneliness in Humans and Rhesus Monkeys (Macaca mulatta)

(2014) John P. Capitanio et al.   PLoS One

In action or inaction? Social approach–avoidance tendencies in major depression

(2014) Sina Radke et al.   PSYCHIATRY RESEARCH

Toward a neurology of loneliness.

(2014) Stephanie Cacioppo et al.   PSYCHOLOGICAL BULLETIN

Pro-social behavior in rats is modulated by social experience

(2014) Inbal Ben-Ami Bartal et al.   eLife

Long-term exposure to intranasal oxytocin in a mouse autism model

(2014) K L Bales et al.   Translational Psychiatry

Desire for social contact, not empathy, may explain “rescue” behavior in rats

(2013) Alan Silberberg et al.   ANIMAL COGNITION

Parallel, Redundant Circuit Organization for Homeostatic Control of Feeding Behavior

(2013) J. Nicholas Betley et al.   CELL

Neural circuits and motivational processes for hunger

(2013) Scott M Sternson et al.   CURRENT OPINION IN NEUROBIOLOGY

Response of the μ-opioid system to social rejection and acceptance

(2013) D T Hsu et al.   MOLECULAR PSYCHIATRY

Diverging neural pathways assemble a behavioural state from separable features in anxiety

(2013) Sung-Yon Kim et al.   NATURE

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

(2013) Gül Dölen et al.   NATURE

Distinct Representations of Cognitive and Motivational Signals in Midbrain Dopamine Neurons

(2013) Masayuki Matsumoto et al.   NEURON

A Quantitative Meta-Analysis of Functional Imaging Studies of Social Rejection

(2013) Stephanie Cacioppo et al.   Scientific Reports

From prediction error to incentive salience: mesolimbic computation of reward motivation

(2012) Kent C. Berridge   EUROPEAN JOURNAL OF NEUROSCIENCE

Differential effects of environmental enrichment and isolation housing on the hormonal and neurochemical responses to stress in the prefrontal cortex of the adult rat: relationship to working and emotional memories

(2012) P. Garrido et al.   JOURNAL OF NEURAL TRANSMISSION

Social ‘wanting’ dysfunction in autism: neurobiological underpinnings and treatment implications

(2012) Gregor Kohls et al.   Journal of Neurodevelopmental Disorders

The pain of social disconnection: examining the shared neural underpinnings of physical and social pain

(2012) Naomi I. Eisenberger   NATURE REVIEWS NEUROSCIENCE

The Mysterious Motivational Functions of Mesolimbic Dopamine

(2012) John D. Salamone et al.   NEURON

Class I histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder

(2012) Andrew G. Foley et al.   NEUROPHARMACOLOGY

Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism

(2012) J. L. Silverman et al.   Science Translational Medicine

The social motivation theory of autism

(2012) Coralie Chevallier et al.   TRENDS IN COGNITIVE SCIENCES

Nucleus Accumbens  -Opioid Receptors Mediate Social Reward

(2011) V. Trezza et al.   JOURNAL OF NEUROSCIENCE

Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Recombinase-Driver Rat Lines: Tools, Techniques, and Optogenetic Application to Dopamine-Mediated Reinforcement

(2011) Ilana B. Witten et al.   NEURON

Empathy and Pro-Social Behavior in Rats

(2011) I. B.-A. Bartal et al.   SCIENCE

Tyrosine hydroxylase and regulation of dopamine synthesis

(2010) S. Colette Daubner et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Social isolation increases morphine intake: behavioral and psychopharmacological aspects

(2010) Sivan Raz et al.   BEHAVIOURAL PHARMACOLOGY

Dopamine in Motivational Control: Rewarding, Aversive, and Alerting

(2010) Ethan S. Bromberg-Martin et al.   NEURON

Fluoxetine but not risperidone increases sociability in the BTBR mouse model of autism

(2010) Kathryn K. Chadman   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The pleasures of play: pharmacological insights into social reward mechanisms

(2010) Viviana Trezza et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Two types of dopamine neuron distinctly convey positive and negative motivational signals

(2009) Masayuki Matsumoto et al.   NATURE

Dissociation of neural networks for anticipation and consumption of monetary and social rewards

(2009) Lena Rademacher et al.   NEUROIMAGE

Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP

(2009) Jill L Silverman et al.   NEUROPSYCHOPHARMACOLOGY

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Anticipation of monetary and social reward differently activates mesolimbic brain structures in men and women

(2009) Katja N. Spreckelmeyer et al.   Social Cognitive and Affective Neuroscience

Perceived social isolation and cognition

(2009) John T. Cacioppo et al.   TRENDS IN COGNITIVE SCIENCES

Functional imaging of the human dopaminergic midbrain

(2009) Emrah Düzel et al.   TRENDS IN NEUROSCIENCES

Ghrelin Modulates Brain Activity in Areas that Control Appetitive Behavior

(2008) Saima Malik et al.   Cell Metabolism

In the Eye of the Beholder: Individual Differences in Perceived Social Isolation Predict Regional Brain Activation to Social Stimuli

(2008) John T. Cacioppo et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Mesolimbic Functional Magnetic Resonance Imaging Activations during Reward Anticipation Correlate with Reward-Related Ventral Striatal Dopamine Release

(2008) B. H. Schott et al.   JOURNAL OF NEUROSCIENCE

Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction

(2008) B. J Everitt et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Affective neuroscience of pleasure: reward in humans and animals

(2008) Kent C. Berridge et al.   PSYCHOPHARMACOLOGY