Article
Chemistry, Analytical
Bianca Maria Pazzi, Dario Pistoia, Giancarla Alberti
Summary: A user-friendly and low-cost RGB detector was developed to read the RGB indexes of microfluidic paper-based analytical devices. The detector showed good reproducibility and achieved satisfactory results in terms of precision and agreement with the pH values measured by a classical pH-meter.
Article
Agronomy
Abdallah E. Elwakeel, Yasser S. A. Mazrou, Aml A. Tantawy, Abdelaziz M. Okasha, Adel H. Elmetwalli, Salah Elsayed, Abeer H. Makhlouf
Summary: The use of automatic systems in agriculture improves product quality and the country's economy. This study aims to design and optimize a low-cost, multi-purpose, RGB color-based fruit sorting sensor. Calibration was performed for the light intensity sensor, conveyor speed sensor, and RGB color sensors, and the results showed that the system achieved comparable performance to manual sorting.
Article
Nanoscience & Nanotechnology
Jian Zhang, Dandan Wang, Yunbin Ying, Hao Zhou, Xiaokai Liu, Xin Hu, Yingxin Chen, Qiang Li, Xuefeng Zhang, Min Qiu
Summary: The study demonstrates a dynamic multi-color display utilizing a humidity-swelling hydrogel layer for metal-insulator-metal (MIM) structure, achieving programmable reflective resonance covering the visible range by controlling PVA thickness and ambient humidity. This novel approach of stepwise and reversible optical tunability using a humidity-sensitive hydrogel material platform presents potential for photonic devices.
Article
Engineering, Environmental
Chenhao Zhu, Lun Zhang, Ao Zou, Weiwen Wang, Jihai Zhang, Aimin Zhang
Summary: Inspired by the color-changing mechanism of chameleons, researchers have developed a multistimulus responsive color-changing hydrogel that can change color based on temperature and pH changes. This hydrogel exhibits high transparency, remarkable mechanical performance, and exceptional electromechanical properties. It has been used to create information encryption and decryption devices, including a dual-level encryption and decryption device based on 2D codes and a multi-level encryption and decryption device that mimics the intelligent color-changing camouflage of chameleons. Additionally, it has been applied in a barrier-free communication system for ALS patients.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Chemical
Joan Morell, Antoni Escobet, Antonio David Dorado, Teresa Escobet
Summary: The mobile phone industry has contributed significantly to the generation of electronic waste and metals scarcity. Recent studies focused on using bioprocesses to extract metals from e-waste. A hardware-software prototype was developed to monitor the real-time concentrations of Fe(III) and Cu(II) through the color change of the solution. The results were validated through comparison with conventional procedures.
Article
Agronomy
Pan Fan, Guodong Lang, Pengju Guo, Zhijie Liu, Fuzeng Yang, Bin Yan, Xiaoyan Lei
Summary: This study proposes a novel method for apple image segmentation using multiple feature selection and gray-centered RGB color space, which can efficiently and accurately identify apple targets. In experiments, the proposed method demonstrated very high accuracy and recall rates.
Article
Chemistry, Multidisciplinary
Yue Chen, Jian Lu
Summary: This paper proposes a multi-loop vehicle counting method under gray mode and RGB mode, which can more accurately detect moving vehicles and better handle different influencing factors, with an accuracy of over 98.5%.
APPLIED SCIENCES-BASEL
(2021)
Article
Polymer Science
Huan Jiang, Yujiao Li, Fangfang Liu, Liping Sheng, Cheng-an Tao, Jianfang Wang
Summary: Some organisms have the ability to change their skin colors to blend with the environment, which is significant for the study of adaptive camouflage materials. This study presents a novel design scheme and successfully prepares an electrically tunable multi-color display angle-independent inverse opal photonic gel. The gel shows high color tunability and durability, making it a promising conductive photonic material.
Article
Materials Science, Multidisciplinary
Katrin Unger, Francesco Greco, Anna Maria Coclite
Summary: The pH sensor tattoo made of temporary tattoo paper, screen-printed poly(3,4-ethylenedioxythiophene):polystyrene sulfonate electrodes, and pH-responsive hydrogel deposited via initiated chemical vapor deposition, can be easily transferred on skin and exhibits excellent conformability to topographical features of epidermis. The sensor also shows reversible pH-responsive swelling of the hydrogel layer and can be operated with non-sophisticated read-out hardware and software.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Engineering, Electrical & Electronic
Chufan Liu, Xin Shu, Lei Pan, Jinlong Shi, Bin Han
Summary: In this paper, we propose a multiscale dual-color space underwater image enhancement network (MSDC-Net) to address the color deviations and hazy effects in underwater images. The network consists of a color correction block and a deep learning-based encoder-decoder architecture, which extracts rich features and produces competitive outputs. Experimental results on real-world and synthetic underwater images demonstrate the outstanding performance of the proposed MSDC-Net.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2023)
Article
Plant Sciences
Qinjian Zhang, Xiangyan Zhang, Yalin Wu, Xingshuai Li
Summary: In this study, a three-stage multi-branch self-correcting trait estimation network (TMSCNet) for RGB and depth images of lettuce was proposed, which showed superior performance in estimating growth traits compared to previous methods. The TMSCNet is an effective method to estimate lettuce traits and will be extended to high-throughput situations.
FRONTIERS IN PLANT SCIENCE
(2022)
Editorial Material
Optics
Yvang Chen, Yuncui Zhang, Xufen Xie, Long Liu, Minjv Fan, Changcheng Sun, Yan Wang, Shuhan Yan
Summary: This paper presents a design method for a high-power optical system with multiple channels, aiming to achieve high-quality color-mixing and uniform lighting. The optical system consists of a multi-channel reflector and a color-mixing component. Simulation results demonstrate that the illumination uniformity of all optical systems is greater than 0.77, and the maximum color difference is 0.014. This optical system can be applied in various fields, such as illumination in machine vision, daylight simulation, and smart lighting.
Article
Optics
Hengzhe Yan, Yuncong Sun, Yiqiao Lin, Feixiang Chu, Wenjie Wan
Summary: Spatial light modulators have enabled complex light field manipulation in various fields, but traditional modulators have limitations in multi-color operations. In this study, we demonstrate a multi-color spatial complex light field modulation using a single binary hologram on digital micromirror devices. By combining neighboring micro-mirror pixels into a superpixel, we achieve independent control of the light field's amplitude and phase, with a phase modulation range exceeding 2π for a single wavelength. This approach enables multi-color light modulations in 2D and 3D holographic planes, as well as the realization of a dual-colored Airy beam.
Article
Polymer Science
Katharina Breul, Sebastian Seiffert
Summary: The rational design of transiently crosslinked polymer gels requires a deep understanding of how molecular and topological factors affect material properties, with distinct differences observed between random PUs and alternating PUs.
Article
Engineering, Electrical & Electronic
Chiara Cosenza, Armando Nicolella, Daniele Esposito, Vincenzo Niola, Sergio Savino
Summary: Computer vision for control is a growing field, with low-cost cameras being widely used in industry and autonomous vehicles. Proper algorithms are crucial for interpreting vision data effectively.
Article
Environmental Sciences
Yu-Jin Jeong, Chang-Ung Kim, Kyung-Soo Lee, Ji Hyung Kim, Seo Young Park, Ahn Young Jeong, Jun Bong Lee, Doo-Jin Kim, Young-Jun Park, Moo-Seung Lee
Summary: In this study, it was found that PM-isolated Pseudomonas stutzeri (PMPS) induces higher levels of inflammatory responses in lung epithelial cells, alveolar cells, and macrophages compared to Pseudomonas stutzeri (PS). The pathogenicity of PMPS is mediated by Toll-like receptors (TLRs) signaling pathways, which also regulate the expression of the antibiotic peptide beta-defensin 3 (BD3) that suppresses PMPS proliferation. Furthermore, pretreatment with PM enhances inflammatory responses and tissue damage caused by PMPS, while reducing BD3 expression.
ENVIRONMENTAL POLLUTION
(2023)
Article
Fisheries
Sib Sankar Giri, Sang Guen Kim, Kang Jeong Woo, Won Joon Jung, Sung Bin Lee, Young Min Lee, Su Jin Jo, Mae Hyun Hwang, JaeHong Park, Ji Hyung Kim, V Sukumaran, Se Chang Park
Summary: This study investigated the effects of Bougainvillea glabra leaf as a feed supplement on the growth, immune response, and disease resistance of carp. The results showed that a dietary supplementation with 40g/kg BG leaf significantly improved the growth performance, immune response, and disease resistance of carp.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Gastroenterology & Hepatology
Yeonjin Je, Kyungdo Han, Jaeyoung Chun, Yuna Kim, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park, Jong Pil Im, Joo Sung Kim
Summary: Abdominal obesity is associated with an increased risk of developing Crohn's disease, but not ulcerative colitis, according to a population-based cohort study in Korea.
JOURNAL OF CROHNS & COLITIS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Changsoo Woo, Kwan Hyeong Jo, Beomseok Sohn, Kisung Park, Hojin Cho, Won Jun Kang, Jinna Kim, Seung-Koo Lee
Summary: A machine learning model was developed and tested to classify the HPV status of OPSCC patients using 18F-FDG PET-derived parameters and an appropriate combination of machine learning methods. The model utilized PET parameters, clinical features, and their combination, and employed various techniques like feature transforms, feature selection, and oversampling for training. The model outperformed those using only PET or clinical parameters in predicting HPV status.
KOREAN JOURNAL OF RADIOLOGY
(2023)
Article
Cell Biology
Audrey Le Floc'h, Kirsten Nagashima, Dylan Birchard, George Scott, Li-Hong Ben, Dharani Ajithdoss, Kaitlyn Gayvert, Annabel Romero Hernandez, Olivier Herbin, Amanda Tay, Pamela Farrales, Chandrashekhar K. Korgaonkar, Hao Pan, Sweta Shah, Vishal Kamat, Ishita Chatterjee, Jon Popke, Adelekan Oyejide, Wei Keat Lim, Jee H. Kim, Tammy Huang, Matthew Franklin, William Olson, Thomas Norton, Lorah Perlee, George D. Yancopoulos, Andrew J. Murphy, Matthew A. Sleeman, Jamie M. Orengo
Summary: The study generated an antibody called REGN7257, which can bind to IL-2RG with high affinity and effectively block signaling of all gamma c cytokines, thus inhibiting T cell-mediated diseases. By using REGN7257, the researchers found that gamma c cytokines play a key role in mouse models of graft-versus-host disease (GVHD) and multiple sclerosis, suggesting that inhibition of gamma c cytokine signaling is a potential strategy for the management of T cell-mediated diseases.
SCIENCE TRANSLATIONAL MEDICINE
(2023)
Article
Medicine, General & Internal
Yuna Kim, Sung Hwan Yoo, Jaeyoung Chun, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park
Summary: This study found that exposing patients to virtual reality (VR) prior to endoscopic procedures can reduce their anxiety levels, leading to less discomfort and incomplete procedures, as well as decreased use of sedative medication. The proportion of patients with high anxiety significantly decreased in the VR group compared to the control group, and patients in the VR group reported higher satisfaction with sedation.
YONSEI MEDICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Dong-Chan Eun, Yong-Ho Lee, Jin-Oh Park, Kyung-Soo Suk, Hak-Sun Kim, Seong-Hwan Moon, Si-Young Park, Byung-Ho Lee, Sang-Jun Park, Ji-Won Kwon, Sub-Ri Park
Summary: In this retrospective study, the clinical and radiological outcomes of patients with multilevel lumbar stenosis who underwent BESS and microscopic ULBD were compared. The results showed that the BESS group had better clinical outcomes, with significant improvements in back and leg pain scores and medication use. Radiological outcomes were also superior in the BESS group. The short-term follow-up period demonstrated the efficacy of multilevel decompression with the BESS technique.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Chemistry, Physical
Juchan Lee, Myung Joon Kim, InverstigationByeong Geun Jeong, Chan Kwon, Yumin Cha, Soo Ho Choi, Ki Kang Kim, Mun Seok Jeong
Summary: The study investigates the effect of sulfur vacancies on the electrical properties of MoS2. After generating sulfur vacancies through treatment with hydrazine, the density of shallow traps increased by a factor of 4, whereas that of deep-level traps increased by a factor of 200. These results indicate that sulfur vacancies induce both deep- and shallow-level traps, with a higher trap density at the deep level.
APPLIED SURFACE SCIENCE
(2023)
Article
Gastroenterology & Hepatology
Hyo-Joon Yang, Young-Il Kim, Ji Yong Ahn, Kee Don Choi, Sang Gyun Kim, Seong Woo Jeon, Jie-Hyun Kim, Sung Kwan Shin, Hyuk Lee, Wan Sik Lee, Gwang Ha Kim, Jae Myung Park, Woon Geon Shin, Il Ju Choi
Summary: This study validated the effectiveness of the eCura system in undifferentiated-type early gastric cancer, and found that close follow-up without additional treatment can be considered for low-risk patients, while additional surgery is recommended for intermediate- and high-risk patients.
Article
Surgery
So Young Han, Hong Jin Yoon, Jie-Hyun Kim, Hye Sun Lee, Jaeyoung Chun, Young Hoon Youn, Hyojin Park
Summary: By analyzing the characteristics of patients with early gastric cancer who underwent ESD, we developed a nomogram to predict the risk of non-CR. This nomogram includes endoscopic features, radiologic findings, and pathology results, and it showed good predictive performance in the external validation.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Cell & Tissue Engineering
Youn Keong Cho, Hyun-Kyung Kim, Soon Sung Kwon, Su-Hee Jeon, June-Won Cheong, Ki Taek Nam, Han-Soo Kim, Sinyoung Kim, Hyun Ok Kim
Summary: To address the blood shortage issue, scientists have been exploring the use of human-induced pluripotent stem cells (hiPSCs) to generate red blood cells (RBCs) in vitro. In this study, hiPSCs were established from peripheral blood, cord blood, and bone marrow, and it was found that peripheral blood and cord blood were the most reliable sources for RBC production in vitro. These findings will aid in the selection of optimal hiPSC lines for clinical RBC production in the future.
STEM CELL RESEARCH & THERAPY
(2023)
Article
Medicine, General & Internal
Oh Chan Kwon, See Young Lee, Jaeyoung Chun, Kyungdo Han, Yuna Kim, Ryul Kim, Min-Chan Park, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park
Summary: This population-based cohort study in Korea found that patients with immune-mediated inflammatory diseases (IMIDs) had a lower risk of all-cause mortality compared to individuals without IMIDs. The risks of cancer-specific and cardiovascular disease-specific mortalities were also lower in IMID patients.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Oh Chan Kwon, Yuna Kim, Jaeyoung Chun, Kyungdo Han, Min-Chan Park, Ryul Kim, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park
Summary: This study aimed to assess whether the presence of immune-mediated inflammatory diseases (IMIDs) confers a higher risk of depression and anxiety in patients with type 2 diabetes (T2DM). The results showed that the existence of gut, joint, and skin IMIDs was associated with a higher risk of depression and anxiety. Patients with multiple IMIDs had a higher risk than those with only one.
FRONTIERS IN MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Sang Jo Han, Su Jung Baik, Young Hoon Yoon, Jie Hyun Kim, Hye Sun Lee, Soyoung Jeon, Hyojin Park
Summary: This study aimed to compare the risk of metabolic syndrome and fatty liver diseases between gastric cancer survivors and non-cancer subjects. The results showed that gastric cancer survivors who underwent surgical treatment had lower risks of metabolic syndrome, fatty liver by ultrasonography, and metabolic dysfunction-associated fatty liver disease (MAFLD) than non-cancer subjects. However, there were no significant differences in the risks between non-surgical gastric cancer survivors and non-cancer subjects.
KOREAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Oncology
Yuna Kim, Yoo Jin Bae, Jie-Hyun Kim, Hyunki Kim, Su-Jin Shin, Da Hyun Jung, Hyojin Park
Summary: Trastuzumab-resistant gastric cancer cells exhibit an epithelial-mesenchymal transition (EMT)-like phenotype, and trastuzumab resistance is promoted by the Wnt/beta-catenin signaling pathway. The Wnt/beta-catenin pathway is a key signaling pathway for trastuzumab resistance in gastric cancer cells.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
