Journal
SENSORS
Volume 19, Issue 21, Pages -Publisher
MDPI
DOI: 10.3390/s19214673
Keywords
highly sensitive; flexible pressure sensor; quantitative evaluation; spinal cord injury
Funding
- National Key R&D Program of China [2017YFA0701101]
- National Natural Sciences Foundation of China [81971164, 81771330, 81330026]
- National Key Basic Research Development Program of the Ministry of Science and Technology of China [2013CB945604]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Key Research and Development Plan of Jiangsu Province [BE2018654]
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Behavioral assessment, such as systematic scoring or biomechanical measurement, is often used to evaluate the extent of the damage and the degree of recovery after spinal cord injury. However, the use of these methods in standardized evaluation is limited because they are subjective and require complex test systems to implement. Here, we report a novel, flexible, microstructure-based pressure sensor and demonstrate its superior sensitivity (235.12 kPa(-1) for 5.5 similar to 135 Pa and 2.24 kPa(-1) for 0.6 similar to 25 kPa), good waterproofness, fast response and recovery times (response time: 8 ms, recovery time: 12 ms), stable response over 8000 loading/unloading cycles, and wide sensing range. These features readily allow the sensor to be comfortably attached to the hindlimbs of mice for full-range, real-time detection of their behavior, such as crawling and swimming, helping to realize quantitative evaluation of animal motor function recovery after spinal cord injury.
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