Review
Engineering, Biomedical
Victor Martinez-Cagigal, Jordy Thielen, Eduardo Santamaria-Vazquez, Sergio Perez-Velasco, Peter Desain, Roberto Hornero
Summary: The study shows that state-of-the-art c-VEP-based BCIs can provide accurate control of the system with a large number of commands, high selection speeds, and even without calibration, suggesting the potential for developing self-paced c-VEP-based portable BCIs for real-world environments. However, there is a lack of validation in real setups, especially with disabled populations, indicating the need for further research and development in this area.
JOURNAL OF NEURAL ENGINEERING
(2021)
Review
Psychiatry
Katelyne Tursini, Irving Remy, Steven Le Cam, Valerie Louis-Dorr, Helene Malka-Mahieu, Raymund Schwan, Gregory Gross, Vincent Laprevote, Thomas Schwitzer
Summary: This study reviews the existing literature to identify key alterations in ERGs and VEP-EEGs of subjects with neurodegenerative and psychiatric disorders, emphasizing the functional role of the visual system. The results showed deficits mainly in the N95 ERG wave and the P100 VEP-EEG wave in Parkinson's, Alzheimer's, and major depressive disorder, reinforcing the link between the retina and the visual cortex for the diagnosis of psychiatric and neurodegenerative diseases.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Psychology, Clinical
Timucin Sezai, Melanie J. Murphy, Nina Riddell, Vinh Nguyen, Sheila G. Crewther
Summary: Migraine is a neurological disorder that causes disability in young adults, especially women. This meta-analysis found altered visual function in patients with migraine during the symptom-free period, including decreased visual evoked potential amplitudes and reduced habituation.
NEUROPSYCHOLOGY REVIEW
(2022)
Article
Psychology, Clinical
Julia M. Longenecker, Victor J. Pokorny, Seung Suk Kang, Cheryl A. Olman, Scott R. Sponheim
Summary: The study examined how high-level visual processing is affected in psychosis and its relation to individual perceptual experiences. Findings showed that smaller N1 and larger NCL amplitudes were associated with object detection, and higher levels of perceptual absorption were correlated with reductions in N400 and a late positive PCA factor.
JOURNAL OF ABNORMAL PSYCHOLOGY
(2021)
Article
Clinical Neurology
Michela Quintiliani, Daniela Ricci, Maria Petrianni, Simona Leone, Lorenzo Orazi, Filippo Amore, Maria Luigia Gambardella, Ilaria Contaldo, Chiara Veredice, Marco Perulli, Elisa Musto, Eugenio Maria Mercuri, Domenica Immacolata Battaglia
Summary: CDKL5 deficiency disorder (CDD) is a developmental encephalopathy caused by pathogenic variants in the gene cyclin-dependent kinase-like 5. This study aims to evaluate the clinical and electrophysiological profile of cerebral visual impairment (CVI) in patients with CDD, and to correlate various aspects of visual function to neurodevelopmental and epileptic features. The results show that visual function is impaired in all patients with CVI being a major feature of CDD, and a diffuse involvement in several behavioral and electrophysiological aspects.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neurosciences
Trine Waage Rygvold, Christoffer Hatlestad-Hall, Torbjorn Elvsashagen, Torgeir Moberget, Stein Andersson
Summary: Long-term potentiation (LTP) is extensively studied in relation to memory and learning. Accumulating evidence suggests that impaired synaptic plasticity plays a role in neuropsychiatric disorders. This study aims to replicate and confirm the use of visual stimulus-specific response modulation as a probe for LTP-like plasticity and explore its association with subclinical depressive symptoms and stress in healthy individuals. Results showed that reduced LTP-like plasticity is associated with higher levels of self-reported symptoms of depression and perceived stress, indicating its sensitivity to psychological distress and its potential as a vulnerability marker for depression.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Review
Neurosciences
Alexander Schielke, Bart Krekelberg
Summary: The author systematically reviewed studies on altered rhythmic responses to visual stimulation in individuals with schizophrenia using steady state visual evoked potentials (SSVEPs). The results indicated that people with schizophrenia exhibited decreased SSVEPs compared to controls across different frequencies and electrode locations, with null results being common. Most studies focused on frequencies within the alpha and beta bands, and investigations of the gamma band were rare.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Dmitri Poltavski, David Biberdorf, Carolina Praus Poltavski
Summary: In the study, it was found that administering OVT protocols before SVT training may lead to greater performance improvements for youth ice hockey players. Both training orders resulted in significant enhancements in visual information processing.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Computer Science, Artificial Intelligence
Victor Martinez-Cagigal, Eduardo Santamaria-Vazquez, Sergio Perez-Velasco, Diego Marcos-Martinez, Selene Moreno-Calderon, Roberto Hornero
Summary: This study proposes the use of non-binary p-ary m-sequences as a more pleasant alternative to traditional binary codes. It is found that all p-ary m-sequences are suitable for achieving high speed and high accuracy in c-VEP-based BCIs, and they can reduce visual fatigue as the base increases.
EXPERT SYSTEMS WITH APPLICATIONS
(2023)
Article
Chemistry, Physical
Ender Ercan, Chih-Chien Hung, Guan-Syuan Li, Yun-Fang Yang, Yan-Cheng Lin, Wen-Chang Chen
Summary: This study investigates the influence of a molecular template strategy on the optical and charge transport properties of organic semiconductors. The results indicate that optimizing the molecular template thickness in phototransistor devices can enhance the memory ratio and retention characteristics. The best heterojunction exhibits visual synaptic functionalities, achieving high pair-pulse facilitation index, low energy consumption, and zero-gate operation.
NANOSCALE HORIZONS
(2023)
Article
Psychology, Biological
Ryan T. Ash, Kerry C. Nix, Anthony M. Norcia
Summary: Repetitive sensory stimulation does not lead to significant neuroplastic changes in response amplitude or temporal processing delays in the visual system. However, steady-state VEPs provide a stable human neurophysiological measure suitable for longitudinal studies.
Article
Physics, Multidisciplinary
Maria Rubega, Emanuela Formaggio, Franco Molteni, Eleonora Guanziroli, Roberto Di Marco, Claudio Baracchini, Mario Ermani, Nick S. Ward, Stefano Masiero, Alessandra Del Felice
Summary: This study investigated the fractal changes in resting-state EEG signals after stroke, finding that both Higuchi index and Tortuosity values were significantly lower in stroke survivors, indicating less complex brain activity. These metrics show promise in tracking behavioral changes post-stroke and may be reliable biomarkers for neurorehabilitation.
Review
Behavioral Sciences
Zeynab Hemmati, Aldo Alberto Conti, Alex Baldacchino
Summary: Opioid use disorder is a global issue, and its effects on women of childbearing age and pregnant women are of increasing concern. This systematic review and meta-analysis found no causal relationship between in utero opioid exposure and future eye abnormalities, but highlighted the need for further research in this area.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Geriatrics & Gerontology
Vincenzo Parisi, Lucia Ziccardi, Lucia Tanga, Gloria Roberti, Lucilla Barbano, Carmela Carnevale, Gianluca Manni, Francesco Oddone
Summary: In open-angle glaucoma, there is impaired postretinal neural conduction along both large and small axons (increased 60' and 15' RCTs) that is related to RGC dysfunction, but independent from the RNFL morphology. The increase of RCT is linearly correlated with the reduction in PERG amplitude and MD values, suggesting that the impairment of postretinal neural structures may contribute to visual field defects in OAG.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Psychology, Multidisciplinary
Joanna Mencel, Anna Jaskolska, Jaroslaw Marusiak, Lukasz Kaminski, Marek Kurzynski, Andrzej Wolczowski, Artur Jaskolski, Katarzyna Kisiel-Sajewicz
Summary: This study demonstrated that computer-aided imagery training (CAIT) can change brain activation patterns in patients with congenital bilateral transverse upper-limb deficiency, affecting motor planning and execution of reaching and grasping movements.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Clinical
Wisteria Deng, Jean Addington, Carrie E. Bearden, Kristin S. Cadenhead, Barbara A. Cornblatt, Daniel H. Mathalon, Diana O. Perkins, Larry J. Seidman, Ming T. Tsuang, Scott W. Woods, Elaine F. Walker, Tyrone D. Cannon
Summary: This study found that there are different covariant trajectories of social anxiety and positive symptoms over time in individuals at clinical high-risk for psychosis. One subgroup showed sustained social anxiety despite moderate recovery in positive symptoms, while the other two subgroups showed recovery in both social anxiety and positive symptoms. The subgroup with sustained social anxiety had poorer long-term functional outcomes and higher levels of genetic and environmental risk factors for psychosis.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Amy Braun, Lu Liu, Carrie E. Bearden, Kristin S. Cadenhead, Barbara A. Cornblatt, Matcheri Keshavan, Daniel H. Mathalon, Thomas H. McGlashan, Diana O. Perkins, Larry J. Seidman, William Stone, Ming T. Tsuang, Elaine F. Walker, Scott W. Woods, Tyrone D. Cannon, Jean Addington
Summary: Bullying is prevalent among individuals at clinical high risk, but does not significantly impact clinical and functional variables or transition to psychosis. However, it is associated with poorer premorbid functioning and a greater risk of violence.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Amanda McCleery, Jonathan K. Wynn, Derek Novacek, Eric A. Reavis, Jack Tsai, Michael F. Green
Summary: The study found that veterans faced significant socioeconomic challenges during the COVID-19 pandemic, with differences in the types of difficulties experienced across different groups. RHV were more likely to experience financial issues and material hardships compared to the other groups, while CTL were most vulnerable to negative financial shocks.
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2022)
Article
Neurosciences
Yash Patel, Jean Shin, Christoph Abe, Ingrid Agartz, Clara Alloza, Dag Alnaes, Sonia Ambrogi, Linda A. Antonucci, Celso Arango, Volker Arolt, Guillaume Auzias, Rosa Ayesa-Arriola, Nerisa Banaj, Tobias Banaschewski, Cibele Bandeira, Zeynep Basgoze, Renata Basso Cupertino, Claiton H. D. Bau, Jochen Bauer, Sarah Baumeister, Fabio Bernardoni, Alessandro Bertolino, Caterina del Mar Bonnin, Daniel Brandeis, Silvia Brem, Jason Bruggemann, Robin Bulow, Juan R. Bustillo, Sara Calderoni, Rosa Calvo, Erick J. Canales-Rodriguez, Dara M. Cannon, Susanna Carmona, Vaughan J. Carr, Stanley V. Catts, Sneha Chenji, Qian Hui Chew, David Coghill, Colm G. Connolly, Annette Conzelmann, Alexander R. Craven, Benedicto Crespo-Facorro, Kathryn Cullen, Andreas Dahl, Udo Dannlowski, Christopher G. Davey, Christine Deruelle, Covadonga M. Diaz-Caneja, Katharina Dohm, Stefan Ehrlich, Jeffery Epstein, Tracy Erwin-Grabner, Lisa T. Eyler, Jennifer Fedor, Jacqueline Fitzgerald, William Foran, Judith M. Ford, Lydia Fortea, Paola Fuentes-Claramonte, Janice Fullerton, Lisa Furlong, Louise Gallagher, Bingchen Gao, Si Gao, Jose M. Goikolea, Ian Gotlib, Roberto Goya-Maldonado, Hans J. Grabe, Melissa Green, Eugenio H. Grevet, Nynke A. Groenewold, Dominik Grotegerd, Oliver Gruber, Jan Haavik, Tim Hahn, Ben J. Harrison, Walter Heindel, Frans Henskens, Dirk J. Heslenfeld, Eva Hilland, Pieter J. Hoekstra, Sarah Hohmann, Nathalie Holz, Fleur M. Howells, Jonathan C. Ipser, Neda Jahanshad, Babette Jakobi, Andreas Jansen, Joost Janssen, Rune Jonassen, Anna Kaiser, Vasiliy Kaleda, James Karantonis, Joseph A. King, Tilo Kircher, Peter Kochunov, Sheri-Michelle Koopowitz, Mikael Landen, Nils Inge Landro, Stephen Lawrie, Irina Lebedeva, Beatriz Luna, Astri J. Lundervold, Frank P. MacMaster, Luigi A. Maglanoc, Daniel H. Mathalon, Colm McDonald, Andrew McIntosh, Susanne Meinert, Patricia T. Michie, Philip Mitchell, Ana Moreno-Alcazar, Bryan Mowry, Filippo Muratori, Leila Nabulsi, Igor Nenadic, Ruth O'Gorman Tuura, Jaap Oosterlaan, Bronwyn Overs, Christos Pantelis, Mara Parellada, Jose C. Pariente, Paul Pauli, Giulio Pergola, Francesco Maria Piarulli, Felipe Picon, Fabrizio Piras, Edith Pomarol-Clotet, Clara Pretus, Yann Quide, Joaquim Radua, J. Antoni Ramos-Quiroga, Paul E. Rasser, Andreas Reif, Alessandra Retico, Gloria Roberts, Susan Rossell, Diego Luiz Rovaris, Katya Rubia, Matthew Sacchet, Josep Salavert, Raymond Salvador, Salvador Sarro, Akira Sawa, Ulrich Schall, Rodney Scott, Pierluigi Selvaggi, Tim Silk, Kang Sim, Antonin Skoch, Gianfranco Spalletta, Filip Spaniel, Dan J. Stein, Olaf Steinstrater, Aleks Stolicyn, Yoichiro Takayanagi, Leanne Tamm, Maria Tavares, Alexander Teumer, Katharina Thiel, Sophia I. Thomopoulos, David Tomecek, Alexander S. Tomyshev, Diana Tordesillas-Gutierrez, Michela Tosetti, Anne Uhlmann, Tamsyn Van Rheenen, Javier Vazquez-Bourgon, Meike W. Vernooij, Eduard Vieta, Oscar Vilarroya, Cynthia Weickert, Thomas Weickert, Lars T. Westlye, Heather Whalley, David Willinger, Alexandra Winter, Katharina Wittfeld, Tony T. Yang, Yuliya Yoncheva, Jende L. Zijlmans, Martine Hoogman, Barbara Franke, Daan van Rooij, Jan Buitelaar, Christopher R. K. Ching, Ole A. Andreassen, Elena Pozzi, Dick Veltman, Lianne Schmaal, Theo G. M. van Erp, Jessica Turner, F. Xavier Castellanos, Zdenka Pausova, Paul Thompson, Tomas Paus
Summary: The study found that group differences in cortical area for attention-deficit/hyperactivity disorder, schizophrenia, and Child Behavior Checklist were dominant in multimodal association cortices across 11 cortical regions. These differences were associated with interregional profiles of prenatal cell-specific gene expression, implying that prenatal cell-specific processes may lead to deviations from typical brain development and vulnerability to mental illness. Additionally, genes coexpressed with radial glia and endothelial and mural cells were enriched with genes related to known pre/perinatal risk factors for psychosis, supporting a neurodevelopmental model of mental illness vulnerability.
BIOLOGICAL PSYCHIATRY
(2022)
Article
Psychiatry
Derek M. Novacek, Jonathan K. Wynn, Amanda McCleery, Eric A. Reavis, Damla Senturk, Catherine A. Sugar, Jack Tsai, Michael F. Green
Summary: The study found that there were few significant differences between Black and White veterans in their initial psychosocial responses to the pandemic. This lack of racial disparities may be attributed to the comprehensive healthcare and social services provided by the Department of Veterans Affairs (VA), and it highlights the resilient nature of social support in Black veterans even in the context of a global pandemic.
AMERICAN JOURNAL OF ORTHOPSYCHIATRY
(2022)
Editorial Material
Neurosciences
Holly K. Hamilton, Daniel H. Mathalon
NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Psychiatry
Lauren T. Catalano, Jonathan K. Wynn, Michael F. Green, James M. Gold
Summary: Diminished social motivation is a core feature of schizophrenia that may be associated with disturbances in social reward processing. This study found that individuals with schizophrenia showed reduced anticipation of social rewards compared to nonsocial rewards. However, both schizophrenia participants and healthy participants exhibited similar responses to social and nonsocial rewards. In addition, the anticipation of social rewards during a task was associated with more social approach behaviors in individuals with schizophrenia. These findings suggest intact social reward liking and impaired wanting in schizophrenia.
SCHIZOPHRENIA RESEARCH
(2022)
Article
Clinical Neurology
Brian J. Roach, Yoji Hirano, Judith M. Ford, Kevin M. Spencer, Daniel H. Mathalon
Summary: This study reanalyzed EEG data and found that patients with schizophrenia showed phase delay in the left hemisphere in the 40-Hz ASSR. This finding supports previous studies showing abnormal auditory cortex function in the left hemisphere in patients with schizophrenia.
CLINICAL EEG AND NEUROSCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Meghan A. Collins, Jie Lisa Ji, Yoonho Chung, Cole A. Lympus, Yvette Afriyie-Agyemang, Jean M. Addington, Bradley G. Goodyear, Carrie E. Bearden, Kristin S. Cadenhead, Heline Mirzakhanian, Ming T. Tsuang, Barbara A. Cornblatt, Ricardo E. Carrion, Matcheri Keshavan, Wiliam S. Stone, Daniel H. Mathalon, Diana O. Perkins, Elaine F. Walker, Scott W. Woods, Albert R. Powers, Alan Anticevic, Tyrone D. Cannon
Summary: Progressive grey matter loss has been observed among individuals who convert to psychosis, and this study found that accelerated cortical thinning precedes psychosis onset and can differentiate converters from non-converters. These findings highlight the importance of identifying neurobiological mechanisms prior to conversion for early intervention.
MOLECULAR PSYCHIATRY
(2023)
Article
Psychiatry
Esra Sefik, Michelle Boamah, Jean Addington, Carrie E. Bearden, Kristin S. Cadenhead, Barbara A. Cornblatt, Matcheri S. Keshavan, Daniel H. Mathalon, Diana O. Perkins, William S. Stone, Ming T. Tsuang, Scott W. Woods, Tyrone D. Cannon, Elaine F. Walker
Summary: This study found clinically relevant deviations in cerebellar cortex and white matter structures among CHR individuals, highlighting the importance of considering the complex interplay between sex and age when studying the neuromaturational substrates of psychosis risk.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Neurosciences
Jonathan K. Wynn, Peter E. Clayson, Michael F. Green, Amy Jimenez, Junghee Lee, Eric A. Reavis, William P. Horan
Summary: People with schizophrenia or other psychotic disorders exhibit deficits in processing facial features, which contribute to difficulties in social interactions. The study used event-related potentials (ERPs) to assess the face processing deficits in individuals with psychosis, their siblings, and healthy comparison participants. The results showed that there were significant differences in ERPs between the psychosis group and the control group, indicating a face-selective N170 ERP component deficit in individuals with psychotic disorders.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Marlena Duda, Armin Iraji, Judith M. Ford, Kelvin O. Lim, Daniel H. Mathalon, Bryon A. Mueller, Steven G. Potkin, Adrian Preda, Theo G. M. Van Erp, Vince D. Calhoun
Summary: By using spatially constrained independent component analysis (scICA), this study found that rsfMRI scans of just 2-5 minutes can provide good clinical utility without significant loss of individual functional network connectivity (FNC) information from longer scan lengths.
HUMAN BRAIN MAPPING
(2023)
Meeting Abstract
Neurosciences
Michael Jacob, Daniel Mathalon, Judith Ford
BIOLOGICAL PSYCHIATRY
(2022)
Meeting Abstract
Neurosciences
Benson Ku, Katrina Aberizk, Jean Addington, Carrie Bearden, Kristin Cadenhead, Tyrone Cannon, Ricardo Carrion, Michael Compton, Barbara Cornblatt, Benjamin Druss, Daniel Mathalon, Diana Perkins, Ming Tsuang, Scott Woods, Elaine Walker
BIOLOGICAL PSYCHIATRY
(2022)
Meeting Abstract
Neurosciences
Nikhilesh Natraj, Thomas Neylan, Leslie Yack, Thomas Metzler, Daniel Mathalon, Anne Richards
BIOLOGICAL PSYCHIATRY
(2022)