Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation

Biochemical and Structural Insights into the eukaryotic translation initiation factor eIF4E

(2019) Laurent Volpon et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Hydrodynamic Behavior of the Intrinsically Disordered Potyvirus Protein VPg, of the Translation Initiation Factor eIF4E and of their Binary Complex

(2019) Jocelyne Walter et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structural and mechanistic basis of mammalian Nudt12 RNA deNADding

(2019) Ewa Grudzien-Nogalska et al.   Nature Chemical Biology

Interactions between the Translation Machinery and Microtubules

(2018) E. M. Chudinova et al.   BIOCHEMISTRY-MOSCOW

Characterization of homodimer interfaces with cross-linking mass spectrometry and isotopically labeled proteins

(2018) Diogo B Lima et al.   Nature Protocols

Chemical shift assignment of the viral protein genome-linked (VPg) from potato virus Y

(2018) Luciana Coutinho de Oliveira et al.   Biomolecular NMR Assignments

A widespread alternate form of cap-dependent mRNA translation initiation

(2018) Columba de la Parra et al.   Nature Communications

Variability in eukaryotic initiation factor iso4E in Brassica rapa influences interactions with the viral protein linked to the genome of Turnip mosaic virus

(2018) Guoliang Li et al.   Scientific Reports

Phase I study of induction chemotherapy with afatinib, ribavirin, and weekly carboplatin and paclitaxel for stage IVA/IVB human papillomavirus-associated oropharyngeal squamous cell cancer

(2017) Lara A. Dunn et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation

(2017) Manuel Miras et al.   PLANT PHYSIOLOGY

eIF4E Resistance: Natural Variation Should Guide Gene Editing

(2017) Anna Bastet et al.   TRENDS IN PLANT SCIENCE

The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity

(2017) Hiba Ahmad Zahreddine et al.   eLife

Regulation of Translation by TOR, eIF4E and eIF2α in Plants: Current Knowledge, Challenges and Future Perspectives

(2017) Ane Sesma et al.   Frontiers in Plant Science

The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex

(2016) Nicola Salvi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR data

(2016) Jinfa Ying et al.   JOURNAL OF BIOMOLECULAR NMR

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

(2016) G.C.P. van Zundert et al.   JOURNAL OF MOLECULAR BIOLOGY

Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E

(2016) Laurent Volpon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas

(2015) B. Culjkovic-Kraljacic et al.   BLOOD

Combined automated NOE assignment and structure calculation with CYANA

(2015) Peter Güntert et al.   JOURNAL OF BIOMOLECULAR NMR

Specific interaction of KIF11 with ZBP1 regulates the transport of  -actin mRNA and cell motility

(2015) T. Song et al.   JOURNAL OF CELL SCIENCE

SIM-XL: A powerful and user-friendly tool for peptide cross-linking analysis

(2015) Diogo B. Lima et al.   Journal of Proteomics

Discovery of m7G-cap in eukaryotic mRNAs

(2015) Yasuhiro FURUICHI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation

(2014) J. Tcherkezian et al.   GENES & DEVELOPMENT

A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E

(2014) S. Assouline et al.   HAEMATOLOGICA

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation

(2014) Hiba Ahmad Zahreddine et al.   NATURE

Steric Effects in Peptide and Protein Exchange with Activated Disulfides

(2013) Jason Kerr et al.   BIOMACROMOLECULES

Evolution of plant eukaryotic initiation factor 4E (eIF4E) and potyvirus genome-linked protein (VPg): A game of mirrors impacting resistance spectrum and durability

(2013) B. Moury et al.   INFECTION GENETICS AND EVOLUTION

The Oncogene eIF4E: Using Biochemical Insights to Target Cancer

(2013) Martin Carroll et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition

(2013) M. J. Osborne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aiding and abetting cancer: mRNA export and the nuclear pore

(2013) Biljana Culjkovic-Kraljacic et al.   TRENDS IN CELL BIOLOGY

Differential accumulation of host mRNAs on polyribosomes during obligate pathogen-plant interactions

(2012) Jackson R. Moeller et al.   Molecular BioSystems

Xwalk: computing and visualizing distances in cross-linking experiments

(2011) Abdullah Kahraman et al.   BIOINFORMATICS

Kinesin molecular motor Eg5 functions during polypeptide synthesis

(2011) Kristen M. Bartoli et al.   MOLECULAR BIOLOGY OF THE CELL

Poisson-Gap Sampling and Forward Maximum Entropy Reconstruction for Enhancing the Resolution and Sensitivity of Protein NMR Data

(2010) Sven G. Hyberts et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Flexibility Allows the Functional Diversity of Potyvirus Genome-Linked Protein VPg

(2010) K. I. Rantalainen et al.   JOURNAL OF VIROLOGY

The Nematode Eukaryotic Translation Initiation Factor 4E/G Complex Works with a trans-Spliced Leader Stem-Loop To Enable Efficient Translation of Trimethylguanosine-Capped RNAs

(2010) A. Wallace et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin

(2009) S. Assouline et al.   BLOOD

Intrinsic disorder in Viral Proteins Genome-Linked: experimental and predictive analyses

(2009) Eugénie Hébrard et al.   Virology Journal

Mutational Analysis of Plant Cap-Binding Protein eIF4E Reveals Key Amino Acids Involved in Biochemical Functions and Potyvirus Infection

(2008) S. German-Retana et al.   JOURNAL OF VIROLOGY

Cis-active RNA elements (CREs) and picornavirus RNA replication

(2008) Benjamin P. Steil et al.   VIRUS RESEARCH