TRPM4-specific blocking antibody attenuates reperfusion injury in a rat model of stroke

Transient Receptor Potential Melastatin 4 channel inhibitor 9-phenanthrol inhibits K+ but not Ca2+ currents in canine ventricular myocytes

(2018) Roland Veress et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Non-Invasive Multimodality Imaging Directly Shows TRPM4 Inhibition Ameliorates Stroke Reperfusion Injury

(2018) Bo Chen et al.   Translational Stroke Research

Profile of intravenous glyburide for the prevention of cerebral edema following large hemispheric infarction: evidence to date

(2018) Zachary A King et al.   Drug Design Development and Therapy

Structures of the calcium-activated, non-selective cation channel TRPM4

(2017) Jiangtao Guo et al.   NATURE

Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial

(2016) Kevin N Sheth et al.   LANCET NEUROLOGY

Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy

(2016) Zhenyu Hu et al.   Scientific Reports

9-Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels

(2015) Sarah K Burris et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy

(2015) R K Adapala et al.   ONCOGENE

Internalization, Trafficking, Intracellular Processing and Actions of Antibody-Drug Conjugates

(2015) Shi Xu   PHARMACEUTICAL RESEARCH

Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events

(2014) Rachael A McCloy et al.   CELL CYCLE

Brain transient receptor potential channels and stroke

(2014) Eric Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects

(2014) Ninda Syam et al.   Frontiers in Cellular Neuroscience

Glyburide is Associated with Attenuated Vasogenic Edema in Stroke Patients

(2013) W. Taylor Kimberly et al.   Neurocritical Care

TRPM4 inhibition promotes angiogenesis after ischemic stroke

(2013) Kok Poh Loh et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Therapeutic Antibodies in Stroke

(2013) Chye Yun Yu et al.   Translational Stroke Research

The DPP-4 Inhibitor Linagliptin Counteracts Stroke in the Normal and Diabetic Mouse Brain: A Comparison With Glimepiride

(2012) V. Darsalia et al.   DIABETES

The Sulfonylurea Receptor 1 (Sur1)-Transient Receptor Potential Melastatin 4 (Trpm4) Channel

(2012) Seung Kyoon Woo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On Potential Interactions between Non-selective Cation Channel TRPM4 and Sulfonylurea Receptor SUR1

(2012) Monica Sala-Rabanal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sulfonylurea Receptor 1 in Central Nervous System Injury: A Focused Review

(2012) J Marc Simard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis

(2012) Benjamin Schattling et al.   NATURE MEDICINE

Sulfonylurea Use Before Stroke Does Not Influence Outcome

(2011) Christopher G. Favilla et al.   STROKE

Role of Nogo-A in Neuronal Survival in the Reperfused Ischemic Brain

(2010) Ertugrul Kilic et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury

(2009) Volodymyr Gerzanich et al.   NATURE MEDICINE

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Temporal Thresholds for Infarction and Hypothermic Protection in Long-Evans Rats

(2008) Megumi Hashimoto et al.   STROKE