4.6 Article

Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-N-acetylisatins Linked at C5 by a Methylene or Oxygen Bridge

Journal

MOLECULES
Volume 24, Issue 23, Pages -

Publisher

MDPI
DOI: 10.3390/molecules24234343

Keywords

antimicrobial peptides; N-acetylisatins; glyoxylamides; peptidomimetics; quorum sensing

Funding

  1. Directorate General of Higher Education, Ministry of Research, Technology and Higher Education, Indonesia through the World Class Professor Program 2019 [T/85/D2.3/KK.04.05/2019]

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The bis-glyoxylamide peptidomimetics have been synthesized from bis-N-acetylisatins linked at C5 by ring-opening with alcohols, amines, and amino acid methyl ester hydrochlorides. X-ray images of single crystals of bis-glyoxylamide peptidomimetics have been obtained.

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